RADx-UP CDCC

RADx-UPCDCC

• 批准号: 10271490
• 负责人: Michael Cohen-Wolkowiez
• 金额: $ 3624.34万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-27 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10271490
• 关键词: 2019-nCoV; Address; Adult; Affect; Back; Behavioral; Biometry; Biostatistics Core; COVID-19; COVID-19 morbidity; COVID-19 pandemic; COVID-19 testing; Cessation of life; Child; Clinical Research; Collaborations; Communities; Community Health Systems; Community of Practice; Consult; Custom; Data; Data Collection; Data Science; Data Sources; Diagnostic Procedure; Effectiveness; Ensure; Ethics; Funding; Future; Goals; Health; Inequality; Informatics; Infrastructure; Leadership; Office of Administrative Management; Outcome; Participant; Pattern; Pilot Projects; Plant Roots; Population Programs; Protocols documentation; Public Health; RADx Underserved Populations; Research; Research Institute; Research Personnel; Research Project Grants; Research Support; SARS-CoV-2 infection; Science; Scientific Advances and Accomplishments; Services; Social Justice; Structure; Testing; Underserved Population; United States National Institutes of Health; Universities; Virus; Vision; Vulnerable Populations; Work; community center; community engaged research; community engagement; data management; data repository; data standards; design; disparity reduction; diverse data; experience; flexibility; health disparity; health equity; improved; infrastructure development; interest; lens; marginalized population; mortality; multidisciplinary; pandemic disease; prevent; programs; recruit; social; statistics

ABSTRACT There is an urgent need to reduce disparities in COVID-19 associated morbidity and mortality outcomes in historically marginalized and vulnerable populations disproportionately affected by the COVID-19 pandemic. To address this need the Rapid Acceleration of Diagnostics for Underserved Populations (RADx-UP) program will support Community-Engaged Testing Research Projects and Social, Ethical and Behavioral Implications (SEBI) Research Projects to understand SARS-CoV-2 infection patterns and increase access and effectiveness of diagnostic methods in underserved and/or vulnerable populations. The Duke Clinical Research Institute (DCRI), the UNC Center for Health Equity Research (CHER), and Community-Campus Partnerships for Health (CCPH) propose to serve as the Coordination and Data Collection Center (CDCC) to provide management, direction, and overall coordination of the RADx-UP consortium. Together, our multidisciplinary experience in project coordination; COVID-19 thought leadership; regulatory science; community engagement; health equity research; social justice; adult and child research; statistics; data science; and clinical research informatics will advance the objectives of the projects in the RADx-UP Program. Our overarching goal is to implement a community-centered approach and establish an effective, flexible, participatory, and sustainable CDCC that will serve as the infrastructure to maximize the community impact of projects in the RADx-UP Program. To achieve this vision, we will establish a program framework comprised of four cores. Our Administration and Coordination Core, in collaboration with NIH scientific staff, will facilitate the work of the RADx-UP Program in overarching administrative management. The COVID-19 Testing Core will advise and guide COVID-19 testing protocols; curate emergent testing data; and administer the Rapid Pilot Studies Program. The Community and Health System Engagement Core will support a community of practice across the RADx-UP Program; provide support in exchanging best practices across communities on recruitment, engagement, and retention of study participants; and coordinate the dissemination of study findings from RADx-UP projects. The Data Science and Biostatistics Core will manage data collection, integration, and sharing for the RADx-UP Program including merging and harmonization of multiple and diverse data sources and provide data standards, data collection design, and biostatistics consulting services. The RADx-UP CDCC goals will be met using established infrastructure and subject matter experts and will be customized to meet the variable needs of the RADx-UP community. Using the highest research standards, our team will accomplish the goals set out by the NIH in managing this critically important collaborative effort.

摘要