Food and Non-Food Self-Regulation in Children's Obesity Risk: A Biopsychosocial Perspective

儿童肥胖风险中的食品和非食品自我调节:生物心理社会视角

基本信息

项目摘要

Childhood obesity remains a significant public health crisis. Most children with obesity are likely to remain obese as they mature and are at risk to experience significantly more lifelong physical and mental health issues, creating significant economic and public health consequences. Thus, identification of the most salient early predictors of obesity is essential. Despite growing evidence that a) self-regulatory skills in food and non-food contexts and appetitive traits significantly impact childhood obesity risk, and b) obesity risk is determined by the interplay between biological, psychological, and home environment factors, this work has occurred largely in isolation within disciplines, greatly hindering the interpretability and application of findings. This proposal describes a longitudinal, interdisciplinary study to leverage our existing sample of 300 mother-child dyads who are diverse with respect to race/ethnicity, socioeconomic status, and obesity risk and have been followed from the prenatal period until children were 2 years old (R01HD093662). We will re-assess these children at ages 3 and 5 and recruit an additional 50 3-year-olds into this study to facilitate future longer-term follow-up into middle childhood and adolescence. We propose a biopsychosocial model of the early development of obesity risk that will clarify (a) the measurement structure of general self-regulation, appetite self-regulation, and food cue reactivity, and the extent to which each has unique versus overlapping antecedents and consequences (Aim 1); and (b) the extent to which general self-regulation and/or appetite self-regulation buffer children from the adverse effects of specific early biological (e.g., hormones related to energy metabolism), psychological/behavioral (e.g., child food cue reactivity, negative emotionality), and social/environmental (e.g., obesogenic home environment, negative parenting) risks on elevated obesity risk at age 5 (Aim 2). This innovative study has critical implications for future targeted preventive interventions, since it will identify which target mechanisms (within the home, individual, or both) in infancy and preschool may be most influential in preventing early obesity risk before it becomes more difficult to reverse. By combining the theoretical and methodologic approaches of developmental and nutritional sciences, this project will help enhance rigor in the methods used to assess distinct aspects of food and non-food reactivity and regulation, which will be applicable to both basic and applied research. Additionally, the proposed study will begin to fill a critical knowledge gap regarding the role of the hormonal milieu in relation to obesity across childhood. Our multidisciplinary team has expertise in observational, physiological, and biological assessments, and will leverage our solid existing collaborations to smoothly implement the proposed study with rigor and efficiency.
儿童肥胖仍然是一个重大的公共卫生危机。大多数肥胖儿童很可能会一直肥胖 随着他们的成熟,并有可能经历更多的终身身心健康问题, 造成重大的经济和公共卫生后果。因此,识别最突出的早期 肥胖的预测因子是必不可少的。尽管越来越多的证据表明,a)食品和非食品的自我监管技能 环境和食欲特征显著影响儿童肥胖风险,和B)肥胖风险由 生物,心理和家庭环境因素之间的相互作用,这项工作主要发生在 学科之间的隔离,极大地阻碍了研究结果的可解释性和应用。这项建议 描述了一个纵向的,跨学科的研究,以利用我们现有的300个母子二人组的样本, 在种族/民族、社会经济地位和肥胖风险方面存在差异, 产前期直至儿童2岁(R 01 HD 093662)。我们将在这些孩子3岁时重新评估他们 和5,并招募额外的50名3岁儿童参加这项研究,以促进未来的长期随访, 儿童和青少年时期。我们提出了一个肥胖风险早期发展的生物心理社会模型 这将澄清(a)一般自我调节,食欲自我调节和食物提示的测量结构 反应性,以及每一个都有独特的与重叠的前因和后果的程度(目标1); 和(B)一般自我调节和/或食欲自我调节缓冲儿童免受不利影响的程度 特定早期生物学效应(例如,与能量代谢相关的激素),心理/行为(例如, 儿童食物线索反应性,负面情绪),和社会/环境(例如,致肥胖的家庭环境, 消极的养育方式)对5岁时肥胖风险升高的风险(目标2)。这项创新的研究具有重要的意义 为未来有针对性的预防干预措施,因为它将确定哪些目标机制(在家庭内, 个体,或两者)在婴儿期和学龄前可能是最有影响力的预防早期肥胖风险之前, 变得更加难以逆转。通过结合发展的理论和方法论的方法, 和营养科学,该项目将有助于提高用于评估不同方面的方法的严谨性, 食品和非食品反应性和监管,这将适用于基础和应用研究。 此外,拟议的研究将开始,以填补一个关键的知识差距,关于激素环境的作用 与儿童期肥胖的关系。我们的多学科团队在观察,生理, 和生物评估,并将利用我们现有的坚实合作,顺利实施 提出了严谨和高效的研究。

项目成果

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Esther M Leerkes其他文献

Esther M Leerkes的其他文献

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{{ truncateString('Esther M Leerkes', 18)}}的其他基金

Biopsychosocial predictors of obesity during the first 2 years of life
生命头两年肥胖的生物心理社会预测因素
  • 批准号:
    10821916
  • 财政年份:
    2023
  • 资助金额:
    $ 61.88万
  • 项目类别:
Biopsychosocial predictors of obesity during the first 2 years of life
生命头两年肥胖的生物心理社会预测因素
  • 批准号:
    10179433
  • 财政年份:
    2018
  • 资助金额:
    $ 61.88万
  • 项目类别:
Biopsychosocial predictors of obesity during the first 2 years of life
生命头两年肥胖的生物心理社会预测因素
  • 批准号:
    10414917
  • 财政年份:
    2018
  • 资助金额:
    $ 61.88万
  • 项目类别:
Biopsychosocial predictors of obesity during the first 2 years of life
生命头两年肥胖的生物心理社会预测因素
  • 批准号:
    9926118
  • 财政年份:
    2018
  • 资助金额:
    $ 61.88万
  • 项目类别:
Biopsychosocial predictors of obesity during the first 2 years of life
生命头两年肥胖的生物心理社会预测因素
  • 批准号:
    9766877
  • 财政年份:
    2018
  • 资助金额:
    $ 61.88万
  • 项目类别:
Identifying Genetic Risk for Maternal Insensitivity and Infant Dysregulation
识别母亲不敏感和婴儿失调的遗传风险
  • 批准号:
    8616772
  • 财政年份:
    2013
  • 资助金额:
    $ 61.88万
  • 项目类别:
Identifying Genetic Risk for Maternal Insensitivity and Infant Dysregulation
识别母亲不敏感和婴儿失调的遗传风险
  • 批准号:
    8511266
  • 财政年份:
    2013
  • 资助金额:
    $ 61.88万
  • 项目类别:
Biological and Behavioral Predictors of Early School Success
早期学校成功的生物和行为预测因素
  • 批准号:
    8509753
  • 财政年份:
    2012
  • 资助金额:
    $ 61.88万
  • 项目类别:
Biological and Behavioral Predictors of Early School Success
早期学校成功的生物和行为预测因素
  • 批准号:
    8841793
  • 财政年份:
    2012
  • 资助金额:
    $ 61.88万
  • 项目类别:
Biological and Behavioral Predictors of Early School Success
早期学校成功的生物和行为预测因素
  • 批准号:
    8663300
  • 财政年份:
    2012
  • 资助金额:
    $ 61.88万
  • 项目类别:

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  • 批准号:
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  • 批准号:
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