Biopsychosocial predictors of obesity during the first 2 years of life

生命头两年肥胖的生物心理社会预测因素

• 批准号: 10821916
• 负责人: Esther M Leerkes
• 金额: $ 28.8万
• 依托单位: UNIVERSITY OF NORTH CAROLINA GREENSBORO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10821916
• 关键词: Address; Adolescence; Adult; Age; Biological Factors; Child; Childhood; Data Collection; Development; Discipline; Family; Funding; Health; Human Resources; Infant; Informal Social Control; Intervention; Life; Longitudinal Studies; Methods; Modeling; Mothers; Obesity; Pathway interactions; Predictive Factor; Prevalence; Prevention; Prevention program; Psychological Factors; Public Health; Research Personnel; Social Interaction; Weight Gain; biopsychosocial; coronavirus disease; early childhood; experience; feeding; infancy; innovation; intervention program; obesity in children; obesity risk; overweight child; peer; prenatal; psychosocial; recruit; social factors

Project Summary The prevalence of childhood obesity is a significant public health crisis. Overweight children experience significantly more health and psychosocial problems compared to their same age peers and are likely to carry these problems with them into adolescence and adulthood. In this proposal, we describe a study of the early development of risk for obesity in childhood. The risk for obesity in early childhood is likely determined by multiple biological, psychological, and social factors that are observable in infancy. We proposed a conceptual model, a biopsychosocial model, of the early development of risk for obesity that focuses on several key biological, psychological, and social factors. Using an experienced team of investigators from multiple disciplines, we proposed to investigate this model with an innovative, multi-method, longitudinal study of infants and their families (n = 300) beginning in the prenatal period that addresses these factors across the first two years of life. Our two key aims focus on understanding (1) factors that predict infant weight gain in the first 6 months of life and (2) the ways in which this weight gain and infant’s social interactions with mothers in feeding and non-feeding contexts predict self-regulation, and subsequent obesity risk at age 2. The study has important implications for the development of targeted prevention and intervention programs for families and children that may be utilized early in development, prior to the onset of weight gain that is difficult to reverse. The purpose of this supplement is to seek funds, primarily for personnel, to complete the original study aims despite COVID-related delays in recruitment and data collection.

项目摘要 儿童肥胖症的患病率是一场重大的公共卫生危机。超重的孩子经历 与同龄同龄人相比，健康和社会心理问题要多得多 这些问题与青少年和成年。在此提案中，我们描述了对早期的研究 童年时期肥胖风险的发展。幼儿肥胖的风险可能取决于 婴儿期可观察到的多个生物学，心理和社会因素。我们提出了一个概念 模型是一种生物心理社会模型，是肥胖风险的早期发展，重点是多个关键 生物学，心理和社会因素。使用来自多个的经验丰富的调查员团队 学科，我们建议通过对婴儿的创新，多方法，纵向研究调查该模型 及其家人（n = 300）从产前期开始，该时期解决了前两个方面的这些因素 生活年。我们的两个关键目的集中于理解（1）预测前6个婴儿体重增加的因素 生命的月份和（2）体重增加和婴儿在喂养方面与母亲的社交互动的方式 和非喂养环境预测自我调节，以及随后在2岁时的肥胖风险。 对针对家庭的有针对性预防和干预计划的制定以及 在体重增加发作之前，可能会在开发早期使用的儿童很难逆转。 该补充的目的是寻求人事的主要资金，以完成原始研究的目的 尽管在招聘和数据收集方面与共同相关的延迟。

项目成果

Protocol for iGrow (Infant Growth and Development Study): biopsychosocial predictors of childhood obesity risk at 2 years.

• DOI: 10.1186/s12889-020-10003-0
• 发表时间: 2020-12-14
• 期刊: BMC public health
• 影响因子: 4.5
• 作者: Leerkes EM;Buehler C;Calkins SD;Shriver LH;Wideman L
• 通讯作者: Wideman L

Maternal sleep problems, depression, and infant negative emotionality are associated with maternal feeding to soothe in early infancy.

母亲的睡眠问题、抑郁症和婴儿的负面情绪与母亲在婴儿早期进行的抚慰喂养有关。

• DOI: 10.1016/j.appet.2022.106098
• 发表时间: 2022
• 期刊: Appetite
• 影响因子: 5.4
• 作者: Leerkes,EstherM;Bailes,LaurenG;Eagleton,SallyG;Buehler,Cheryl;Shriver,LenkaH;Wideman,Laurie
• 通讯作者: Wideman,Laurie

Bidirectional associations between maternal controlling feeding and food responsiveness during infancy.

• DOI: 10.3389/fpubh.2022.975067
• 发表时间: 2022
• 期刊: FRONTIERS IN PUBLIC HEALTH
• 影响因子: 5.2
• 作者: Eagleton, Sally G.;Shriver, Lenka H.;Buehler, Cheryl;Wideman, Laurie;Leerkes, Esther M.
• 通讯作者: Leerkes, Esther M.

Racial Disparities in Neighborhood and Household Socioeconomic Disadvantage Predict Postpartum Weight Retention.

• DOI: 10.1016/j.focus.2022.100029
• 发表时间: 2022-12
• 期刊: AJPM focus
• 作者: Avorgbedor, Forgive;McCoy, Thomas P;Wideman, Laurie;Shriver, Lenka H;Buehler, Cheryl;Leerkes, Esther M
• 通讯作者: Leerkes, Esther M

Infant appetite and weight gain in early infancy: Moderating effects of controlling feeding styles.

婴儿早期的婴儿食欲和体重增加：控制喂养方式的调节作用。

• DOI: 10.1016/j.appet.2022.106139
• 发表时间: 2022
• 期刊: Appetite
• 影响因子: 5.4
• 作者: Shriver,LenkaH;Eagleton,Sally;Lawless,MeganC;Buehler,Cheryl;Wideman,Laurie;Leerkes,EstherM
• 通讯作者: Leerkes,EstherM