Biopsychosocial predictors of obesity during the first 2 years of life

生命头两年肥胖的生物心理社会预测因素

• 批准号: 10821916
• 负责人: Esther M Leerkes
• 金额: $ 28.8万
• 依托单位: UNIVERSITY OF NORTH CAROLINA GREENSBORO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10821916
• 关键词: Address; Adolescence; Adult; Age; Biological Factors; Child; Childhood; Data Collection; Development; Discipline; Family; Funding; Health; Human Resources; Infant; Informal Social Control; Intervention; Life; Longitudinal Studies; Methods; Modeling; Mothers; Obesity; Pathway interactions; Predictive Factor; Prevalence; Prevention; Prevention program; Psychological Factors; Public Health; Research Personnel; Social Interaction; Weight Gain; biopsychosocial; coronavirus disease; early childhood; experience; feeding; infancy; innovation; intervention program; obesity in children; obesity risk; overweight child; peer; prenatal; psychosocial; recruit; social factors

Project Summary The prevalence of childhood obesity is a significant public health crisis. Overweight children experience significantly more health and psychosocial problems compared to their same age peers and are likely to carry these problems with them into adolescence and adulthood. In this proposal, we describe a study of the early development of risk for obesity in childhood. The risk for obesity in early childhood is likely determined by multiple biological, psychological, and social factors that are observable in infancy. We proposed a conceptual model, a biopsychosocial model, of the early development of risk for obesity that focuses on several key biological, psychological, and social factors. Using an experienced team of investigators from multiple disciplines, we proposed to investigate this model with an innovative, multi-method, longitudinal study of infants and their families (n = 300) beginning in the prenatal period that addresses these factors across the first two years of life. Our two key aims focus on understanding (1) factors that predict infant weight gain in the first 6 months of life and (2) the ways in which this weight gain and infant’s social interactions with mothers in feeding and non-feeding contexts predict self-regulation, and subsequent obesity risk at age 2. The study has important implications for the development of targeted prevention and intervention programs for families and children that may be utilized early in development, prior to the onset of weight gain that is difficult to reverse. The purpose of this supplement is to seek funds, primarily for personnel, to complete the original study aims despite COVID-related delays in recruitment and data collection.

项目摘要 儿童肥胖症的流行是一个重大的公共健康危机。超重儿童体验 与同龄的同龄人相比，他们的健康和心理社会问题要多得多，而且很可能 这些问题伴随着他们进入青春期和成年期。在这个提案中，我们描述了一项对早期 儿童时期肥胖风险的发展。儿童早期肥胖的风险可能由以下因素决定 在婴儿期可观察到的多种生物、心理和社会因素。我们提出了一个概念性的 肥胖风险早期发展的生物心理社会模型，关注以下几个关键因素 生物、心理和社会因素。使用来自多个国家的经验丰富的调查团队 学科，我们建议用一种创新的、多方法的、对婴儿的纵向研究来研究这一模型。 和他们的家人(n=300)从产前开始，在前两个阶段解决这些因素 生命中的岁月。我们的两个关键目标集中在了解(1)预测前6个月婴儿体重增加的因素 (2)婴儿体重增加的方式以及婴儿在喂养过程中与母亲的社会互动 而不喂食的环境预示着自我调节能力，以及随后在2岁时肥胖的风险。 为家庭和儿童制定有针对性的预防和干预方案的重要意义 儿童在发育早期可能被利用，在体重增加开始之前，这是难以逆转的。 这一补充的目的是寻求资金，主要用于人员，以完成原来的研究目标 尽管在招募和数据收集方面出现了与CoVID有关的延误。

项目成果

Protocol for iGrow (Infant Growth and Development Study): biopsychosocial predictors of childhood obesity risk at 2 years.

• DOI: 10.1186/s12889-020-10003-0
• 发表时间: 2020-12-14
• 期刊: BMC public health
• 影响因子: 4.5
• 作者: Leerkes EM;Buehler C;Calkins SD;Shriver LH;Wideman L
• 通讯作者: Wideman L

Maternal sleep problems, depression, and infant negative emotionality are associated with maternal feeding to soothe in early infancy.

母亲的睡眠问题、抑郁症和婴儿的负面情绪与母亲在婴儿早期进行的抚慰喂养有关。

• DOI: 10.1016/j.appet.2022.106098
• 发表时间: 2022
• 期刊: Appetite
• 影响因子: 5.4
• 作者: Leerkes,EstherM;Bailes,LaurenG;Eagleton,SallyG;Buehler,Cheryl;Shriver,LenkaH;Wideman,Laurie
• 通讯作者: Wideman,Laurie

Bidirectional associations between maternal controlling feeding and food responsiveness during infancy.

• DOI: 10.3389/fpubh.2022.975067
• 发表时间: 2022
• 期刊: FRONTIERS IN PUBLIC HEALTH
• 影响因子: 5.2
• 作者: Eagleton, Sally G.;Shriver, Lenka H.;Buehler, Cheryl;Wideman, Laurie;Leerkes, Esther M.
• 通讯作者: Leerkes, Esther M.

Racial Disparities in Neighborhood and Household Socioeconomic Disadvantage Predict Postpartum Weight Retention.

• DOI: 10.1016/j.focus.2022.100029
• 发表时间: 2022-12
• 期刊: AJPM focus
• 作者: Avorgbedor, Forgive;McCoy, Thomas P;Wideman, Laurie;Shriver, Lenka H;Buehler, Cheryl;Leerkes, Esther M
• 通讯作者: Leerkes, Esther M

Infant appetite and weight gain in early infancy: Moderating effects of controlling feeding styles.

婴儿早期的婴儿食欲和体重增加：控制喂养方式的调节作用。

• DOI: 10.1016/j.appet.2022.106139
• 发表时间: 2022
• 期刊: Appetite
• 影响因子: 5.4
• 作者: Shriver,LenkaH;Eagleton,Sally;Lawless,MeganC;Buehler,Cheryl;Wideman,Laurie;Leerkes,EstherM
• 通讯作者: Leerkes,EstherM