Methodologic Core

项目摘要 解决风湿性疾病的种族差异，如系统性红斑狼疮和系统性红斑狼疮。 硬化症需要跨学科的方法，涉及强大的方法组成部分。总体 CCCR方法核心的目标是提高研究人员在以下方面进行的研究质量： CCCR研究基地，并提供有关风湿性关节炎少数民族健康的调查领导 疾病为了在CCCR中实现这些目标，方法核心有4个目标：1）提供 对CCCR研究基地进行定量指导; 2）开展研究，开发新的生物统计学方法; 3)参与临床和翻译研究者的教育发展;以及4）担任联络员 CCCR研究基地和其他定量专家之间的交流。核心由4名博士教师组成， 生物统计学，生物信息学和流行病学方面的专业知识，他们都有很好的记录， 与风湿病学家合作，临床相关方法开发和教育。通过 与我们的CTSA计划和其他重要资源的互动，核心也将能够利用 根据需要增加专业知识。通过创新技术实现这些目标， 将有助于继续确保MUSC是流变学研究的领先实体。

PROJECT SUMMARY Addressing racial disparities in rheumatic diseases as complex as systemic lupus erythematosus and systemic sclerosis requires interdisciplinary approaches that involve strong methodological components. The overarching objectives of the CCCR Methodologic Core are to enhance the quality of research conducted by investigators in the CCCR Research Base and to provide leadership on investigations relevant to minority health in rheumatic diseases. To achieve these objectives within the CCCR, the Methodologic Core has 4 aims: 1) provide quantitative guidance to the CCCR Research Base; 2) conduct research to develop novel biostatistics methods; 3) participate in educational development of clinical and translational investigators; and 4) serve as liaisons between the CCCR Research Base and other quantitative experts. The Core is comprised of 4 PhD faculty with expertise in biostatistics, bioinformatics, and epidemiology, all of whom have a strong track record of collaboration with rheumatologists, clinically-relevant methods development, and education. Through interactions with our CTSA program and other important resources, the Core will also be able to leverage additional expertise as needed. By achieving these aims through innovative techniques, the Methodologic Core will help continue to ensure that MUSC is a leading entity in rheumatologic research.