Research Education Component

研究教育部分

• 批准号: 10264194
• 负责人: ROBERTA EILEEN BRINTON
• 金额: $ 19.07万
• 依托单位: ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-05 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10264194
• 关键词: Academic Training; Address; Advanced Development; Aging; Alzheimer disease prevention; Alzheimer' s Disease; Alzheimer' s disease related dementia; Arizona; Biological Markers; Clinical; Collaborations; Communities; Complement; Data; Data Science; Diagnosis; Disease; Education and Outreach; Ethics; Fostering; Future; Goals; Hispanic-serving Institution; Hispanics; Human Resources; Leadership; Mentorship; Minority; Modeling; National Institute of Neurological Disorders and Stroke; Native Americans; Native-Born; Neurodegenerative Disorders; Occupational activity of managing finances; Outcome; Personnel Management; Persons; Population Heterogeneity; Positioning Attribute; Postdoctoral Fellow; Recommendation; Reproducibility; Research; Research Personnel; Resources; Science; TRADD gene; Training Programs; Translational Research; Underrepresented Populations; United States National Institutes of Health; blood-based biomarker; career; career development; clinically relevant; cohort; college; education research; educational atmosphere; experience; faculty research; fight against; fighting; innovation; multidisciplinary; next generation; personalized strategies; pre-doctoral; preclinical study; prevent; programs; rate of change; recruit; science education; skill acquisition; skills; success; symposium; undergraduate research; undergraduate student

SUMMARY/ABSTRACT - RESEARCH EDUCATION COMPONENT (REC) The Arizona ADRC REC training program addresses goals and objectives of the National Alzheimer's Project Act (NACA) "To prevent and effectively treat Alzheimer's Disease and Related Dementias (AD/ADRD) by 2025.” It is aligned with NIH AD and ADRD Research Summit recommendations, the ADRC's overarching theme (blood- based biomarkers (“BBBs) in the diagnosis, preclinical study and prevention of AD/ADRD, its aggressively collaborative model, and our commitment to help develop the next generation of AD/ADRD researchers, including those from diverse backgrounds. We propose a personalized strategy to engage and advance junior faculty and research associates to conduct innovative integrative AD/ADRD research that is clinically relevant, translationally valid, scientifically reproducible and includes under-represented groups. To address gaps in academic training, the AZ ADRC REC will advance the development of skills necessary to achieve success in 21st century team science, leadership, personnel and financial management and collaborative ethical research; further develop and apply their expertise and skills in the fight against AD and ADRD; and capitalize on our programs and Resource Center for Minority Aging Research (RCMAR) partnerships to advance research careers and studies involving persons from Hispanic, Native American and other under-represented communities. To build the pipeline of future AD/ ADRD researchers, we propose an experience dependent mentorship strategy in which the AZ ADRC REC complements NIH / NIA training programs for postdoctoral, predoctoral and undergraduate research fellows and spans ethnic, cultural and professional diversity. Strategies to achieve these goals include: Specific Aim 1: Personalized AD/ADRD Research Career Plan for 21st Century Team Science; Specific Aim 2: Leadership and Ethics at the Rate of Change in the 21st Century and Specific Aim 3: Building the Alzheimer's Research Career Pipeline for the Future. Outcomes of these endeavors will advance the overall ADRC goals articulated in the NIH/NIA Alzheimer's Disease Research Centers RFA-AG-20-004 including:  “Create a dynamic educational environment that supports disruptive and transformative research.  Accelerate translational research across the spectrum of disease.  Demonstrate scientifically productive interactions across NIH and other Federal Center programs.  Provide a mechanism for data science education relevant to neurodegenerative disease research.  Facilitate career development to increase diversity of leadership positions within the Center.  Education and outreach activities aligned with Clinical Core for recruitment of diverse populations.”

总结/摘要-研究教育部分（REC） 亚利桑那州ADRC REC培训计划涉及国家阿尔茨海默病项目的目标和目的 法案（NACA）“到2025年预防和有效治疗阿尔茨海默病和相关痴呆症（AD/ADRD）”。 它符合NIH AD和ADRD研究峰会的建议，ADRC的首要主题（血液- 基于生物标志物（“BBB”）的AD/ADRD的诊断、临床前研究和预防， 合作模式，以及我们致力于帮助开发下一代AD/ADRD研究人员， 包括来自不同背景的人。我们提出了一个个性化的战略，以吸引和促进初级 教师和研究人员进行创新的综合AD/ADRD研究是临床相关的， 理论上有效，科学上可重复，包括代表性不足的群体。为了弥补 学术培训，AZ ADRC REC将推进必要的技能发展，以取得成功， 21世纪世纪团队科学、领导力、人事和财务管理以及协作伦理研究; 进一步发展和应用他们的专业知识和技能，以对抗AD和ADRD;并利用我们的 计划和少数民族老龄化研究资源中心（RCMAR）合作伙伴关系，以推进研究事业 以及涉及西班牙裔、美洲原住民和其他代表性不足的社区的研究。 为了建立未来AD/ ADRD研究人员的管道，我们提出了一个经验依赖型导师制 AZ ADRC REC补充NIH / NIA博士后，博士前和博士后培训计划的战略 本科研究员和跨越种族，文化和专业的多样性。实现这些目标的战略 目标包括：具体目标1：21世纪团队科学的个性化AD/ADRD研究职业计划; 具体目标2：世纪变革速度下的领导和道德 阿尔茨海默氏症研究未来的职业管道。这些努力的结果将推动整体 NIH/NIA阿尔茨海默病研究中心RFA-AG-20-004中阐述的ADRC目标包括： “创造一个动态的教育环境，支持颠覆性和变革性的研究。 加速跨疾病谱的转化研究。 在NIH和其他联邦中心项目中展示科学上富有成效的互动。 提供与神经退行性疾病研究相关的数据科学教育机制。 促进职业发展，增加中心内领导职位的多样性。 “与临床核心相一致的教育和推广活动，以招募不同的人群。