Summer Program for Undergraduate Rising Stars (SPURS), a Columbia University biomedical sciences pipeline program

项目总结 本申请是对R25 NS076445的竞争性续订，以资助以下人员的暑期计划： “代表学生(马刺)”更名为“本科生新秀暑期计划” (马刺)“，通过RFA-HL-21-168机制。拟议资金的100%将用于支持 麻省理工学院的学生从事神经科学项目，这些项目对NINDS的使命至关重要。马刺将提供一种 为有才华的非裔美国人/黑人和西班牙裔美国人提供密集的本科生物医学研究经验 拉丁裔(A)、美洲原住民/阿拉斯加原住民、太平洋岛民、第一代和经济上的弱势群体 哥伦比亚大学神经科学专业的学生。马刺每年将培养14名优秀学生 他们是神经科学和生物医学研究相关领域的本科生。 大学的马刺项目提供紧张的本科生在校园的研究体验 哥伦比亚大学内科医生和外科医生学院(P&S)招收来自以下背景的有才华的学生 在生物医学研究中的代表性不足。马刺参赛者被纽约城市大学录取 约克(CUNY)高级学院，包括亨特学院、布鲁克林学院、皇后区学院和城市学院以及大学 以及全国范围内的大学。热刺提供基础神经科学和翻译神经科学方面的广泛培训 研究，并提高了学生通过追求科学的职业生涯的可能性 高级学位(医学博士和/或博士)。为代表不足的少数族裔本科生扩大就业机会 学生参与高质量、集中和持续的神经科学研究体验， 马刺项目充分利用了神经科学领域的杰出资源和教师导师。在过去的几年里 在资助期间，申请人数激增，在接下来的一段时间里，我们建议继续高度培训 合格的少数族裔学生参与者。学生们在九个暑期的时间里在 NINDS支持的哥伦比亚大学神经科学家导师(目前为89名哥伦比亚大学 研究人员获得NINDS支持)。除了在神经科学方面的具体培训外，学生们还 接受了深入的研究方法培训，包括：(A)设计和分析实验；(B) 通过期刊俱乐部和科学伦理讨论对科学文献进行批判性阅读；(C) 在实验室会议上介绍科学成果；(D)在招贴会上介绍他们的研究； (E)向科学家的听众口头介绍他们的研究；和(F)职业咨询。最后， 研究培训将在独特的丰富环境中提供，包括每周与以下人员举行会议- 代表了生物医学研究中的少数群体榜样。马刺计划解决了以下关键需求 增加高素质少数族裔学员进入神经科学领域的渠道。

PROJECT SUMMARY This application is for a competitive renewal of R25 NS076445 to fund “Summer Program for Under- represented Students (SPURS)”, to be renamed “Summer Program for Undergraduate Rising Stars (SPURS)”, through the RFA-HL-21-168 mechanism. 100% of the proposed funding will be used to support SPURS students working on neuroscience projects central to the mission of NINDS. SPURS will provide an intensive, undergraduate biomedical research experience for talented African-American/Black, Hispanic Latino(a), Native American/Alaska Native, Pacific Islander, first-generation, and economically disadvantaged students in the neurosciences at Columbia University. SPURS will train 14 outstanding students each year who are undergraduates majoring in areas relevant to neuroscience and biomedical research.Columbia University's SPURS Program provides an intense undergraduate research experience on the campus of Columbia's College of Physicians & Surgeons (P&S) for talented students from backgrounds that are under-represented in biomedical research. SPURS participants are accepted from the City University of New York (CUNY) senior colleges, including Hunter, Brooklyn, Queens, and City Colleges, as well as universities and colleges nationwide. SPURS provides extensive training in basic and translational neuroscience research, and enhances the likelihood that the students will achieve a career in science by pursuing an advanced degree (M.D. and/or Ph.D.). To expand opportunities for under-represented minority undergraduate students to participate in high quality, focused and sustained research experiences in the neurosciences, the SPURS program leverages outstanding resources and faculty mentors in the neurosciences. Over the last funding period, applications have soared and in the upcoming period, we propose to continue training highly qualified minority student participants. Students perform hands-on research for nine summer weeks under the mentorship of NINDS-supported Columbia University neuroscientists (currently 89 Columbia University researchers receive NINDS support). In addition to specific training in neuroscience, the students have received in-depth training in research methodology including: (a) the design and analysis of experiments; (b) critical reading of scientific literature through journal clubs and discussions of ethics in science; (c) the presentation of scientific results at laboratory meetings; (d) presentation of their research at poster sessions; (e) an oral presentation of their research to an audience of scientists; and (f) career counseling. Finally, the research training will be provided in a uniquely enriching setting that includes weekly meetings with under- represented minority role models in biomedical research. The SPURS program addresses the critical need to increase the pipeline of highly qualified minority trainees into neuroscience.