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Otolaryngology Training in Immunology, Virology and Molecular Biology

免疫学、病毒学和分子生物学的耳鼻喉科培训

基本信息

批准号：
10599353
负责人：
Rick A Friedman
金额：
$ 28.17万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-07-01 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10599353
关键词：
Address Area Attention Basic Science Biomedical Research Career Choice Clinical Clinical Research Clinical Sciences Collaborations Communicable Diseases Conflict (Psychology)Counseling Development Disease Education Education Projects Ensure Evidence Based Medicine Experimental Designs Fellowship Female Funding Future Genomic medicine Goals Grant Head and neck structure Healthcare Immune Immunologics Immunology Immunotherapy Inflammatory Institution Instruction Length Malignant Neoplasms Manuscripts Mediating Medicine Mentors Methods Minority Mission Molecular Molecular Biology National Institute on Deafness and Other Communication Disorders Natural Immunity Otolaryngologist Otolaryngology Patient Care Patients Physicians Play Preparation Public Health Reproducibility Research Research Ethics Research Personnel Research Project Grants Research Training Residencies Role Science Scientist Structure Supervision Surgical Specialties Teacher Professional Development Techniques Therapeutic Time Training Training Programs Translational Research Underrepresented Populations Virus Diseases Wages Work Writing academic preparation career clinical training data quality education research experience medical schools medical specialties pathogen programs receptor recruit responsible research conduct skills success symposium virology

项目摘要

PROJECT SUMMARY/ABSTRACT The education of clinician-scientists is of paramount importance to the field of Otolaryngology. The need for interfaces between science and medicine, the importance of clinicians that value scientific research, and the increased importance of evidence-based medicine in health care all argue for research training of physicians. Moreover, the impact of immunological mechanisms in many ENT diseases has received increased attention in the past decade, with an increase immune/inflammatory therapeutics in our field. Immunotherapy has proven to be highly effective in several forms of cancer. Yet Otolaryngology remains behind many other areas of medicine in immunology research. As an example, the area of innate immunity mediated by pathogen receptors has seen a dramatic expansion in the broader field of immunology and infectious diseases over the past 20 years, and the head and neck represent a major pathogen interface. However, only within the last few years has an increase in innate immune research been seen in our field. The availability of molecular methods has transformed research in immunology and other areas of biomedicine, molecular therapies are in active development, and the era of genomic medicine has arrived. Clinician-scientists well trained in molecular biology are therefore needed. Finally, research into viral diseases could not be more relevant at the current time. Over the past 30 years, UCSD Otolaryngology has expanded its immunology, virology and molecular research, resulting in an established cadre of scientists. These investigators provide a fertile training ground for clinicians who wish to pursue these arenas of research, to provide ENT with well-trained clinician-scientists. We propose to continue our clinician-scientist resident research training program under the R25 mechanism. Our program addresses the major barriers to research by clinicians by providing training in: 1) experimental design and scientific techniques; 2) research collaboration and teambuilding; 3) grant and scientific manuscript writing; 4) managing the conflict between clinical work and research; and 5) preparation for academic medicine. The trainees for this program will be selected from MD's who wish to pursue eighteen months of research training during their Otolaryngology residency, consisting of the R25 year and additional periods of research training embedded in clinical training. Trainees from underrepresented groups will be actively sought. Trainees will receive advanced basic science, translational or clinical research training in the application of advanced immunology, virology and molecular biology methods to research problems within the NIDCD arena. Research training will extend throughout residency, to provide continuity and avoid a significant training gap. Trainees will also receive instruction in research ethics, methods to ensure data quality and reproducibility, responsible conduct of research, and the preparation of initial review board applications. Finally, we will encourage choice of a career including research with specific education.

项目总结/文摘

项目成果

期刊论文数量（11）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

The Feasibility of Outpatient Type I Thyroplasty with Laryngeal Reinnervation.

门诊 I 型甲状腺成形术伴喉神经支配的可行性。

DOI：
10.1177/01455613221116326
发表时间：
2022
期刊：
Ear, nose, & throat journal
影响因子：
0
作者：
Ostrander,BenjaminT;Vahabzadeh-Hagh,AndrewM
通讯作者：
Vahabzadeh-Hagh,AndrewM

Endoscopic Repair of a Full Thickness Hypopharyngeal Defect Using Acellular Dermal Matrix.

使用脱细胞真皮基质内窥镜修复全层下咽缺损。

DOI：
10.1177/01455613231206293
发表时间：
2023
期刊：
Ear, nose, & throat journal
影响因子：
0
作者：
Ostrander,BenjaminT;Kolb,FredericJ;Weissbrod,PhilipA
通讯作者：
Weissbrod,PhilipA

Free flap jaw reconstruction with dental implantation: A single-institution experience.

自由瓣颌重建并种植牙：单一机构的经验。

DOI：
10.1002/hed.27683
发表时间：
2024
期刊：
Head & neck
影响因子：
0
作者：
Ostrander,BenjaminT;Meller,Leo;Harmon,Matthew;Archambault,Katya;Kristallis,Thanos;Hammer,Daniel;Orosco,RyanK
通讯作者：
Orosco,RyanK

Comparison of Postoperative Outcomes in Cystic Versus Solid Vestibular Schwannoma in a Multi-institutional Cohort.

多机构队列中囊性前庭神经鞘瘤与实性前庭神经鞘瘤术后结果的比较。

DOI：
10.1097/mao.0000000000004062
发表时间：
2024
期刊：
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
影响因子：
0
作者：
Zhang,Lisa;Ostrander,BenjaminT;Duhon,Bailey;Moshitaghi,Omid;Lee,Joshua;Harris,Micah;Hardesty,DouglasA;Prevedello,DanielM;Schwartz,MarcS;Dodson,EdwardE;Friedman,RickA;Adunka,OliverF;Ren,Yin
通讯作者：
Ren,Yin

New Medical Device and Therapeutic Approvals in Otolaryngology: State of the Art Review of 2021.

DOI：
10.1177/2473974x221126495
发表时间：
2022-07
期刊：
OTO OPEN
影响因子：
1.5
作者：
Choi, Alexander M.;Brenner, Michael J.;Gorelik, Daniel;Erbele, Isaac D.;Crowson, Matthew G.;Kadkade, Prajoy;Takashima, Masayoshi;Santa Maria, Peter L.;Hong, Robert S.;Rose, Austin S.;Ostrander, Benjamin T.;Rabbani, Cyrus C.;Morrison, Robert J.;Weissbrod, Philip A.;Tate, Alan D.;Kain, Joshua J.;Lina, Ioan A.;Shaffer, Scott R.;Ahmed, Omar G.
通讯作者：
Ahmed, Omar G.