Administrative Core_Pizzagalli

行政核心_Pizzagalli

• 批准号: 10601122
• 负责人: Diego A Pizzagalli
• 金额: $ 42.01万
• 依托单位: MCLEAN HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-04-15 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10601122
• 关键词: Adherence; Affect; Affective; Anxiety Disorders; Award; Behavior; Budgets; Cells; Clinical; Collaborations; Communities; Community Health; Community Outreach; Computer Models; Corpus striatum structure; Data; Decision Making; Development; Diffusion; Disease; Education and Outreach; Educational Activities; Ensure; Evaluation; Faculty; Fellowship; Fostering; Functional disorder; General Hospitals; General Population; Genes; Goals; Grant; Hand; Hospitals; Human; Institution; Investigation; Knowledge; Maps; Massachusetts; Mental Depression; Mental Health; Mental disorders; Mentorship; Midbrain structure; Mission; Modeling; Molecular Target; Monitor; Mood Disorders; Mus; National Institute of Mental Health; Output; Parameter Estimation; Patient Self-Report; Patient advocacy; Physiology; Play; Population; Postdoctoral Fellow; Program Development; Progress Reports; Research; Research Domain Criteria; Research Personnel; Resource Sharing; Resources; Role; Schools; Scientist; Series; Site; Students; Technology; Training; Training and Education; Universities; Washington; Woman; advocacy organizations; approach avoidance behavior; biomarker identification; career development; cohesion; community engagement; data sharing; effective therapy; graduate student; improved; interest; medical schools; meetings; minority scientist; neuropsychiatric disorder; nociceptin; nonhuman primate; novel; operation; outreach; outreach program; programs; recruit; symposium; synergism; timeline; translational neuroscience; undergraduate student; web site

PROJECT SUMMARY (Administrative Core, Core Leader: Pizzagalli, McLean Hospital) The overarching goals of the Administrative Core, which will be led by the Center Director, are to (1) oversee all scientific and administrative operations across projects and participating scientists; (2) maximize integration and synergies across the four Projects and the Computational Modeling Core; (3) coordinate and implement training and educational activities within the Center, with a specific focus on attracting new investigators to the field of affective translational neuroscience from diverse background; and (4) interact with existing resources to enhance the research, education and community outreach goals of the center. Several initiatives and activities will be pursued to accomplish these important goals. First, the Administrative Core will oversee day-to-day activities of the Center, including adherence to regulatory requirements, budget monitoring, and submission of progress reports. Second, the Core will monitor the progress of each Project and will ensure that data and information are shared across Center components. Third, the Core will be responsible to support the proposed scientific priorities by organizing regular meetings for Center Investigators (monthly), Internal Advisory Board (twice a year), External Advisory Board (once a year), and a monthly Center Speaker Series. Fourth, the Core will foster the educational/training component of the Center by ensuring ample opportunities for junior faculty, postdoctoral fellows and students to play important roles in the proposed projects. These career development efforts will be supplemented by providing annual pilot grants to junior faculty and postdoctoral fellows to spearhead independent projects expected to further augment the Center’s goals. Moreover, and leveraging numerous T32 training grants and fellowship opportunities at sites across Projects, the Core will prioritize recruitment and retention of women and minority scientists. The Center Director and Project PIs all have a strong mentorship track record (as manifested by the many K, NRSAD, and NARSAD grants they have sponsored over the years), and plan to maintain this commitment to mentorship during the award period. Fifth, the Core will develop, maintain and promote a Center website to engage the larger scientific community and general public; provide a platform to share information across Center investigators; and provide a platform for data and resource sharing (e.g., to make freely available novel computational models). In addition, in year 5, the Core will organize a Public Symposium to engage the community and educate them about depression and mental health more generally as well as the scientific discoveries that emerged from the Center grant. These efforts will be augmented by a School Outreach Program. Sixth, the Core will proactively engage in outreach efforts to the regional mental health community and patient advocacy organizations, with a particular focus on explaining novel conceptualizations of neuropsychiatric disorders (e.g., RDoC) and novel treatment targets. Finally, the Core will be responsible for providing a programmatic evaluation of Center’s activities, output and impact, which will occur in close collaboration with an annual review by the External Advisory Board.

项目总结（管理核心，核心负责人：Pizzagalli，姆克林医院） 由中心主任领导的行政核心的总体目标是：（1）监督 跨项目和参与科学家的所有科学和行政运作;（2）最大限度地整合 四个项目和计算建模核心之间的协同作用;（3）协调和实施 中心内的培训和教育活动，特别侧重于吸引新的调查人员到中心 来自不同背景的情感转化神经科学领域;（4）与现有资源互动， 加强中心的研究、教育和社区外展目标。若干倡议和活动 我们将努力实现这些重要目标。首先，行政核心将监督日常工作， 中心的活动，包括遵守监管要求、预算监控和提交 进度报告。第二，核心小组将监测每个项目的进展情况，并将确保数据和 信息在Center组件之间共享。第三，核心将负责支持拟议的 通过组织中心研究者定期会议（每月一次）、内部咨询委员会 （每年两次），外部咨询委员会（每年一次），以及每月的中心发言人系列。第四，核心 将通过确保初级教师有充足的机会， 博士后研究员和学生在拟议的项目中发挥重要作用。这些职业发展 将通过向初级教师和博士后研究员提供年度试点赠款来补充这些努力， 领导独立项目，预计将进一步扩大中心的目标。此外，利用 许多T32培训赠款和奖学金的机会，在各地的项目，核心将优先考虑 招聘和留住妇女和少数民族科学家。中心主任和项目PI都有一个 强大的指导跟踪记录（如他们拥有的许多K，NRSAD和NARSAD赠款所证明的那样 多年来赞助），并计划在奖励期间保持这种对指导的承诺。第五、 核心将开发、维护和推广中心网站，以吸引更大的科学界， 公众;提供一个平台，在中心研究者之间共享信息;并提供一个平台， 数据和资源共享（例如，以使新的计算模型免费可用）。此外，在第五年， 核心将组织一个公共研讨会，让社区参与进来，教育他们有关抑郁症的知识， 更普遍的精神健康以及从中心赠款中出现的科学发现。这些 学校外联方案将加强这方面的努力。第六，核心小组将积极开展外联活动 区域精神卫生社区和患者倡导组织的努力，特别侧重于 解释神经精神障碍的新概念（例如，RDoC）和新的治疗靶点。 最后，核心小组将负责对中心的活动、产出和 这将与外部咨询委员会的年度审查密切合作进行。