Optimizing the Pulse Physiology Engine to Meet Medical Simulation Community Needs

优化脉冲生理学引擎以满足医学模拟社区的需求

• 批准号: 10609281
• 负责人: Rachel Clipp
• 金额: $ 36.28万
• 依托单位: KITWARE, INC.
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10609281
• 关键词: Address; Administrative Supplement; Adverse event; Anatomy; Architecture; Area; Benchmarking; Cholecystectomy; Code; Communities; Computer Models; Computer software; Data; Development; Disease; Documentation; Educational workshop; Effectiveness; Ensure; Environment; Equipment Malfunction; Event; Feedback; Funding Opportunities; Goals; Government; Grant; Human Resources; Industry; Injury; Java; Language; Machine Learning; Medical; Methods; Minor; Modeling; Operative Surgical Procedures; Outcome Assessment; Patient Care; Patients; Performance; Physiologic pulse; Physiological; Physiology; Publications; Pythons; Running; Software Tools; Source Code; Speed; Surgeon; Surgical Error; System; Technology; Testing; Time; Training; Visualization; base; bile duct; care providers; computing resources; design; haptics; improved; interest; medical specialties; models and simulation; open data; open source; parent grant; physiologic model; resilience; response; simulation; skill acquisition; skills; software development; symposium; technology development; tool; verification and validation; virtual; virtual reality simulator; virtual surgery

1 Project Summary 2 The objective of our current R01 project, “Surgical Simulator for Improving Skill Proficiency and Resilience”, is 3 to design, develop, and validate methods by which simulation technologies can be used by practicing surgeons. 4 This project is extending the interactive Medical Simulation Toolkit (iMSTK) by developing software templates 5 for rare and adverse event simulation including physiological modeling, automating skill assessment, and 6 performance management in surgical simulations, which are critical for building powerful simulation applications 7 for practicing surgeons. Physiology remains an aspect of interactive real-time simulation that is rarely dealt with. 8 In most instances physiological models are developed separately without coordination with interactive surgical 9 simulation. In our current grant, we are integrating Kitware’s open source Pulse Physiology Engine with iMSTK 10 to build a closed-loop physiology model that handles local physiology changes and global, systemic physiological 11 responses. We are demonstrating these new developments by building a virtual surgical simulator for 12 cholecystectomy with bile duct injury and other rare complications that occur in this type of surgery. The goals 13 of our supplement are to 1) improve the computational efficiency of Pulse, 2) advance the external interfaces for 14 Pulse, including the Unity Asset, and 3) engage and promote Pulse to expand the user community. These goals 15 will support the parent grant by 1) improving computational efficiency to ensure that Pulse does not engage 16 critical computational resources required for graphical render, displacement and force calculations, and haptic 17 interface integration and 2) making Pulse more readily accessible via external interfaces, such as Unity, which 18 is the simulator environment for our parent grant. The supplement will also have a significant impact on medical 19 simulation in general by improving the accessibility of the Pulse via additional external interfaces, such as an 20 Unreal Plugin and interface language support, including Python, C#, and Java. We plan to engage the community 21 via publications, software releases, blog posts, and a workshop at a computational modeling conference. We 22 will engage Kitware’s well-respected software development team with the Key Personnel of the parent grant to 23 advance the Pulse platform and engage with our community of users. 24 25

1项目概要 2我们目前的R01项目的目标，“提高技能熟练度和弹性的手术模拟器”，是 3.设计、开发和验证模拟技术可供执业外科医生使用的方法。 4本项目通过开发软件模板扩展交互式医学模拟工具包（iMSTK） 5用于罕见和不良事件模拟，包括生理建模、自动化技能评估，以及 6手术模拟中的性能管理，这对于构建强大的模拟应用程序至关重要 七是做好外科医生。生理学仍然是交互式实时模拟的一个方面，很少涉及。 8在大多数情况下，生理模型是单独开发的，没有与交互式外科手术协调。 9模拟。在我们目前的资助中，我们正在将Kitware的开源脉冲生理学引擎与iMSTK集成 10建立处理局部生理变化和全局、全身生理变化的闭环生理模型。 11个答案我们正在通过建立一个虚拟手术模拟器来展示这些新的发展， 12胆囊切除术伴胆管损伤及其他此类手术中发生的罕见并发症。的目标 我们的13个补充是1）提高Pulse的计算效率，2）改进外部接口， 14 Pulse，包括Unity资产，以及3）参与并推广Pulse以扩大用户社区。这些目标 15将通过1）提高计算效率以确保Pulse不会参与 图形渲染、位移和力计算以及触觉控制所需的16个关键计算资源 17接口集成，2）使Pulse更容易通过外部接口访问，例如Unity， 18号是我们父母补助金的模拟环境。补充剂也将对医疗产生重大影响 19模拟一般通过改进的可访问性脉冲通过额外的外部接口，如 20 Unreal插件和接口语言支持，包括Python、C#和Java。我们计划让社区 21通过出版物，软件发布，博客文章和计算建模会议上的研讨会。我们 22将聘请Kitware备受尊敬的软件开发团队与母公司赠款的关键人员， 23推进Pulse平台并与我们的用户社区互动。 24 25