Regenerative Engineering of Musculoskeletal Tissues- a Convergence Doctoral Training Program

肌肉骨骼组织再生工程-融合博士培训项目

• 批准号: 10604923
• 负责人: CATO T. LAURENCIN
• 金额: $ 16.14万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10604923
• 关键词: Musculoskeletal; Regenerative engineering; Tissues; Training Programs

PROJECT SUMMARY / ABSTRACT We propose a novel NIAMS doctoral T32 Program, Regenerative Engineering of Musculoskeletal Tissues: A Convergence Doctoral Training Program, which offers inter-disciplinary research areas at the University of Connecticut (UConn) combining biomedical science and engineering faculties. Regenerative Engineering is defined as the Convergence of advanced materials science, stem cell science, physics, developmental biology and clinical translation for the regeneration of complex tissues and organ systems. The T32 Program will enroll 3 Ph.D. candidates per year and support each for 2 years of Graduate School. The students will be drawn from graduate programs at UConn (School of Medicine and School of Engineering). The students will then apply for T32 support at the end of Year 1 of graduate school to be supported for Years 2-3. They will all receive their Ph.D. from the Graduate School at UConn. The T32 Program will offer trainees a broad level of expertise in research and instruction based on the research, educational, and clinical experiences of the biomedical and engineering faculty who serve as preceptors. Trainees will become experts in regenerative engineering and its foundations to work towards the alleviation of human disease and musculoskeletal injuries by means of tissue regeneration. Musculoskeletal regeneration is a field ripe for an inventive approach based on convergence to address challenging issues, advance technology and further fundamental knowledge for therapeutic applications. At the center of the Convergence approach is the understanding that new solutions in regeneration will take place through an ‘un-siloed’ approach. Thus, Regenerative Engineering welcomes ideas and research across a gamut of disciplines. The T32 Program has preceptorship commitments from 20 distinguished faculty at UConn (representing Biomedical Engineering, Cell Biology, Computer Science, Genetics and Genome Sciences, Materials Science, Mechanical Engineering, Molecular Biology and Biophysics, Oral Health, Orthopedic Surgery). This eminent group of investigators is well funded and published to provide the primary research training and serve as role models for doctoral trainees. The T32 Program goals are to educate, support and enhance the training of individuals dedicated to careers as independent clinical translational and basic scientists in regenerative engineering. Our Program strengths include its interdisciplinary and collaborative research in biomedical science and engineering, interactions with diverse trainees and faculty, training in contemporary research methodologies, and successful preceptors. T32 Program administration through the Connecticut Convergence Institute for Translation in Regenerative Engineering will provide the experience to recruit diverse trainees, including minorities, implement the curriculum, and train a new cadre of convergence scientists.

项目摘要/摘要 我们提出了一个新的NIAMS博士T32项目-肌肉骨骼再生工程 组织：融合博士培训计划，提供跨学科研究领域 康涅狄格大学(UConn)将生物医学科学和工程学院结合在一起。 再生工程被定义为先进材料科学、干细胞 科学、物理学、发育生物学和复杂组织再生的临床翻译 和器官系统。T32计划每年招收3名博士生，每人支持2名 研究生院的几年。这些学生将来自康涅狄格州大学(学院)的研究生课程 医学院和工程学院)。然后，学生将在第一年结束时申请T32支持 研究生院的学生将获得2-3年的资助。他们都将从研究生那里获得博士学位 在康涅狄格州大学上学。T32计划将为学员提供广泛的研究和专业知识水平 基于生物医学和临床的研究、教育和临床经验的教学 作为教员的工程学教师。学员将成为再生工程方面的专家 及其基金会致力于通过以下方式减轻人类疾病和肌肉骨骼损伤 组织再生的方法。肌肉骨骼再生是一个适合创造性方法的成熟领域 以融合为基础，解决具有挑战性的问题、推进技术和进一步的基础 用于治疗应用的知识。融合方法的核心是理解 再生方面的新解决方案将通过“非孤立”的方法来实现。因此，再生性 工程学欢迎各种学科的想法和研究。T32计划有 康涅狄格州大学20名杰出教员(代表生物医学)的授课承诺 工程学、细胞生物学、计算机科学、遗传学和基因组科学、材料科学、 机械工程、分子生物学和生物物理学、口腔健康、整形外科)。这 著名的调查小组有充足的资金和出版，以提供初步的研究培训和 作为博士生的榜样。T32计划的目标是教育、支持和提高 培养致力于作为独立临床、翻译和基础科学家的职业的个人 在再生工程方面。我们的计划优势包括跨学科和协作性 生物医学科学和工程方面的研究，与不同学员和教员的互动，培训 在当代研究方法方面，和成功的教导者。T32计划管理 通过康涅狄格州汇聚学院翻译的再生工程将提供 招募包括少数民族在内的不同学员的经验，实施课程，并培训新的 汇聚的科学家队伍。