Diversity Supplement to R01 DC017757

R01 DC017757 的多样性补充

• 批准号: 10610599
• 负责人: Joel D Mainland
• 金额: $ 1.14万
• 依托单位: MONELL CHEMICAL SENSES CENTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10610599
• 关键词: Algorithms; Black race; Characteristics; Chemical Structure; Chemicals; Code; Collection; Color; Communities; Complex; Complex Mixtures; Country; Data; Data Set; Descriptor; Detection; Development; Eating; Enrollment; Face; Food; Food Preferences; Frequencies; Funding; Health; Human; Learning; Ligands; Machine Learning; Mass Fragmentography; Measurement; Measures; Methods; Modeling; Modernization; Molecular Structure; Neurosciences; Non-linear Models; Numerical value; Odors; Olfactory Pathways; Perception; Play; Process; Psychophysics; Research; Research Personnel; Role; Science; Sensory; Smell Perception; Stimulus; Techniques; Technology; Training; Translating; Vision; Visual; Vocabulary; Work; apprenticeship; auditory stimulus; base; career development; computer monitor; design; experience; experimental study; high dimensionality; improved; in silico; interest; laboratory experience; machine learning algorithm; member; novel; physical property; predictive modeling; predictive test; preference; programs; receptor; relating to nervous system; single molecule; visual stimulus

PROJECT SUMMARY Modern technology makes it possible to capture a visual scene as a photograph, alter it, send it to another country nearly instantaneously, and store it without concern for degradation. None of this is currently possible in olfaction. Although perfumers and flavorists are adept at mixing odorous molecules to produce a desired perceptual effect, the rules underlying this process are poorly understood at a quantitative level. Current methods for displaying odors to a subject are akin to requiring a Polaroid of every visual stimulus of interest. A more efficient method for probing the olfactory system would be to use a set of 'primary odors'—some limited number of odors from which all other complex odors could be reproduced by appropriate mixtures. Both auditory and visual stimuli have been digitized, and this will eventually be possible in olfaction as well. Predicting odor from chemical structure has been a problem in the field since its inception, but recent advances in machine learning algorithms have made great progress in analogous problems, such as facial recognition. This diversity supplement proposal seeks funds to enable Joshua Nsubuga, a Black U.S. citizen, to learn how to design experiments, analyze data, and conduct human sensory studies. We have crafted a training plan that draws on both our laboratory's experience and Monell's Science Apprenticeship Program to facilitate Mr. Nsubuga's technical, intellectual, and career development.

项目总结 现代技术使捕捉视觉场景成为可能，将其作为照片进行更改，并将其发送给另一张照片 国家几乎瞬间，并存储它，而不担心退化。这一切目前都不可能实现。 在嗅觉方面。尽管香水师和调味师擅长将气味分子混合在一起，以生产出所需的 知觉效应，这一过程背后的规律在数量层面上知之甚少。当前 向受试者显示气味的方法类似于需要每个感兴趣的视觉刺激的宝丽来。一个 探测嗅觉系统的更有效的方法是使用一组“主要气味”--有些是有限的 所有其他复杂气味可以通过适当的混合物重现的气味数量。两者都有 听觉和视觉刺激已经数字化，这最终也将在嗅觉中实现。 从化学结构预测气味从一开始就是该领域的一个问题，但最近的进展 在机器学习中，算法在人脸识别等类似问题上取得了很大的进展。 这项多样性补充提案寻求资金，使美国黑人公民约书亚·恩苏布加能够学习如何 设计实验，分析数据，并进行人体感官研究。我们已经制定了一项训练计划， 借鉴我们实验室的经验和莫内尔的科学学徒计划，为莫内尔先生提供便利。 Nsubuga的技术、智力和职业发展。