The Einstein-Montefiore Diversity, Equity, Inclusion, and Accessibility (DEIA) Mentorship program

爱因斯坦-蒙蒂菲奥里多样性、公平、包容性和可及性 (DEIA) 导师计划

• 批准号: 10605137
• 负责人: John Greally
• 金额: $ 41.71万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-15 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10605137
• 关键词: Address; Administrative Supplement; Age; Aging; Award; Basic Science; Biology of Aging; Cells; Climate; Clinical; Clinical Research; Code; Communities; Consult; County; DNA Sequence; Data; Development; Development Plans; Educational Curriculum; Effectiveness of Interventions; Environment; Epigenetic Process; Event; Extramural Activities; Faculty; Fostering; Foundations; Funding; Future; Genetic; Genetic Transcription; Goals; Health system; Hispanic; Hispanic Graduate Student; Human; Indigenous; Individual; Institution; Institutional Practice; Intention; Investments; Leadership; Mentors; Mentorship; Mission; Monitor; Motivation; New York; Outcome; Parents; Participant; Persons; Population Heterogeneity; Postdoctoral Fellow; Program Development; Research; Resources; Source; Testing; Time; Training; Trust; Underrepresented Populations; Untranslated RNA; Variant; Wages; Work; base; career; career development; clinical care; design; disorder risk; diversity and equity; doctoral student; effectiveness testing; genetic variant; insight; interest; leadership development; medical schools; organizational climate; programs; response; skills; success; technique development; tool; training opportunity

ABSTRACT This is a proposal for a supplement to the R01 entitled Understanding cellular and transcriptional regulatory changes in human aging. It responds to NOT-OD-22-057, the Notice of Special Interest (NOSI): Administrative Supplements to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) Mentorship. The parent R01 studies the ‘epigenetic’ events involved with ageing in humans, extending beyond the typical consideration of cellular reprogramming events into systematic cell subtype proportional changes, and the unmasking of functional DNA sequence variants with age. As this project permits the development of techniques that permit insights into DNA sequence variants in non- coding regions that can influence the risk of disease in people of diverse genetic ancestry, represented strongly by our community here in the Bronx, the project has attracted individuals from diverse, under-represented groups, with diversity supplements awarded to an indigenous postdoctoral fellow and a Hispanic graduate student. While such funding is individually very valuable, it has become apparent that there needs to be a more general institutional climate in place to foster the careers of those from typically excluded groups. The NOSI described above provides the opportunity to fund an institution-wide program to enhance the careers of these under- represented colleagues. We describe an intensive one-year plan to develop and implement a new curriculum towards this goal. We will leverage existing institutional resources, develop new programs, and harness external consulting resources in a new, integrated course. We will protect the time of program participants and faculty, and will collect information systematically about the program so that we will, at the end of the year, have collected enough data to direct how ongoing resource investment should be targeted. Our goal is to guide our institution’s development of an equitable environment that provides very active training for those from minoritized groups, developing the future leaders who will amplify the benefits of the training to an increasingly large part of our academic community.

抽象的 这是 R01 的补充提案，题为“了解细胞和转录调控” 人类衰老的变化。它响应 NOT-OD-22-057，特别利益通知 (NOSI)：行政 表彰多样性、公平性、包容性和可及性 (DEIA) 指导方面卓越表现的补充。 母体 R01 研究与人类衰老相关的“表观遗传”事件，超出了典型的范围 将细胞重编程事件考虑为系统细胞亚型比例变化，以及 随着年龄的增长，功能性 DNA 序列变异被揭开。 由于该项目允许开发能够深入了解非DNA序列变异的技术 可以影响不同遗传血统的人患病风险的编码区，具有很强的代表性 通过我们在布朗克斯的社区，该项目吸引了来自不同、代表性不足的个人 团体，向一名土著博士后研究员和一名西班牙裔毕业生提供多样性补充 学生。 虽然此类资金单独来说非常有价值，但显然需要有一个更普遍的资金 培养来自典型被排斥群体的人的职业生涯的制度氛围。 NOSI 描述 上述提供了资助一项全机构计划的机会，以提高这些不足的职业生涯 代表同事。 我们描述了一个为期一年的密集计划，旨在开发和实施新课程以实现这一目标。我们将 利用现有机构资源、开发新项目并利用外部咨询资源 新的综合课程。 我们将保护项目参与者和教师的时间，并将系统地收集有关项目的信息 计划，以便我们在年底收集足够的数据来指导持续的资源 投资要有针对性。 我们的目标是指导我们机构发展一个公平的环境，提供非常积极的培训 对于来自少数群体的人，培养未来的领导者，将培训的好处扩大到 我们学术界中越来越大的一部分。