STATE MEDICAL CANNABIS LAWS, CHRONIC PAIN, AND OPIOIDS: A MIXED-METHODS APPROACH
国家医用大麻法、慢性疼痛和阿片类药物:混合方法
基本信息
- 批准号:10609894
- 负责人:
- 金额:$ 58.61万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-07-01 至 2025-04-30
- 项目状态:未结题
- 来源:
- 关键词:AdultAffectAmendmentAnticonvulsantsArthritisAttitudeBehaviorCannabisCannabis policyCertificationClinicalDataData SourcesDrynessEffectivenessEnvironmentFeesGuidelinesHeadacheHealthcareHealthcare SystemsIndividualInterviewLawsLeadLiteratureLocationLow Back PainMedicalMedical MarijuanaMedicareMedicare claimMethodsOpioidOpioid RotationOutcomeOverdosePainPain managementPatientsPatternPerceptionPersonsPhysical therapyPhysiciansPlant LeavesPoisoningPoliciesPolicy MakerPrimary Care PhysicianQuasi-experimentRecommendationReportingResearchRoleSalesSamplingSocietiesSpecialistSurveysTimeVariantarthritic painchronic painchronic pain managementchronic pain patientclinical carecohortcomparison groupcostdesignevidence baseexperiencefibromyalgia paininnovationinsightmarijuana usemarijuana use disordermarijuana usermedical examinationnon-cancer chronic painnon-opioid analgesicopioid epidemicopioid overdoseopioid useopioid use disorderpain patientpainful neuropathypharmacologicprescription opioid
项目摘要
ABSTRACT
Thirty-three states and D.C. have enacted medical cannabis laws allowing patients with chronic non-cancer
pain to use cannabis, when recommended by a physician, to manage their condition. Policymakers are
increasingly considering state medical cannabis laws as a potential solution to the U.S. opioid crisis, with the
idea that some patients may substitute cannabis in place of prescription opioids for treatment of chronic non-
cancer pain and reduce rates of opioid use disorder and overdose as a result. However, rigorous evidence is
lacking: no studies have examined the effects of state medical cannabis laws on opioid-related outcomes
among a cohort of patients with chronic non-cancer pain. Further, no existing research has examined how
state medical cannabis laws affect chronic non-cancer pain patients’ receipt of guideline-concordant non-opioid
pain treatments or how such laws affect cannabis use disorder and poisoning among those with chronic non-
cancer pain conditions like low back pain or arthritis. Critically, no prior studies have considered how the
considerable variation in provisions and implementation across state medical cannabis laws, and within states
over time as states amend their laws and change implementation rules, affect outcomes for chronic pain
patients. Our study uses a mixed-methods approach incorporating quasi-experimental difference-in-differences
analyses; qualitative interviews with state policy and healthcare leaders; and representative surveys of
physicians who treat and patients who experience chronic non-cancer pain to fill these research gaps. Using
50-state data sources including Medicare and Optum UnitedHealthcare administrative claims data, we will
examine the effects of state medical cannabis laws on receipt of prescription opioid and guideline-concordant
non-opioid pharmacologic (e.g., anticonvulsants) and non-pharmacologic (e.g., physical therapy) pain
treatments (Aim 1). We will also use these data to examine the effects of state medical cannabis laws on
receipt of treatment for opioid use disorder, opioid overdose, cannabis use disorder, and cannabis poisoning
among patients with chronic non-cancer pain (Aim 2). We will conduct qualitative interviews with state policy
and healthcare system leaders to characterize implementation of state medical cannabis laws for treatment of
chronic non-cancer pain (Aim 3). Finally, we will conduct representative surveys with primary care physicians,
pain specialists, and patients with chronic non-cancer pain in states with medical cannabis laws. Surveys will
capture key attitudes and reported behaviors related to medical cannabis laws, including the degree to which
physicians report recommending and patients report using cannabis in place of opioids for treatment of chronic
non-cancer pain (Aim 4). In all Aims, we will consider how differences in law provisions and implementation
influence chronic pain treatment. Results will yield information needed by state decision-makers considering
implementing new medical cannabis laws as well as those considering changes to existing medical cannabis
laws’ provisions and implementation.
摘要
项目成果
期刊论文数量(10)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
The state of the evidence on the association between state cannabis laws and opioid-related outcomes: A review.
- DOI:10.1007/s40429-021-00397-1
- 发表时间:2021-12
- 期刊:
- 影响因子:4.3
- 作者:Tormohlen, Kayla N;Bicket, Mark C;White, Sarah;Barry, Colleen L;Stuart, Elizabeth A;Rutkow, Lainie;McGinty, Emma E
- 通讯作者:McGinty, Emma E
Perceived Safety and Effectiveness of Cannabis and Other Types of Pain Treatments Among Adults with Chronic Noncancer Pain in U.S. States with Medical Cannabis Programs.
美国各州开展医用大麻计划的慢性非癌性疼痛成人对大麻和其他类型疼痛治疗的安全性和有效性的认知。
- DOI:10.1007/s11606-023-08163-x
- 发表时间:2023
- 期刊:
- 影响因子:5.7
- 作者:White,SarahA;Bicket,MarkC;McGinty,EmmaE
- 通讯作者:McGinty,EmmaE
Patient Responses to Surgery-relevant Screening for Opioid and Other Risky Substance Use Before Surgery: A Pretest-posttest Study.
患者对术前阿片类药物和其他危险物质使用的手术相关筛查的反应:一项前后测试研究。
- DOI:10.1093/pm/pnac190
- 发表时间:2023
- 期刊:
- 影响因子:0
- 作者:Fernandez,AnneC;Aslesen,Heidi;Golmirzaie,Goodardz;Stanton,Sofea;Gunaseelan,Vidhya;Waljee,Jennifer;Brummett,ChadM;Englesbe,Michael;Bicket,MarkC
- 通讯作者:Bicket,MarkC
Use of Cannabis and Other Pain Treatments Among Adults With Chronic Pain in US States With Medical Cannabis Programs.
- DOI:10.1001/jamanetworkopen.2022.49797
- 发表时间:2023-01-03
- 期刊:
- 影响因子:13.8
- 作者:Bicket, Mark C.;Stone, Elizabeth M.;McGinty, Emma E.
- 通讯作者:McGinty, Emma E.
Protocol: mixed-methods study of how implementation of US state medical cannabis laws affects treatment of chronic non-cancer pain and adverse opioid outcomes.
- DOI:10.1186/s13012-020-01071-2
- 发表时间:2021-01-07
- 期刊:
- 影响因子:0
- 作者:McGinty EE;Tormohlen KN;Barry CL;Bicket MC;Rutkow L;Stuart EA
- 通讯作者:Stuart EA
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Emma Elizabeth McGinty其他文献
Emma Elizabeth McGinty的其他文献
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{{ truncateString('Emma Elizabeth McGinty', 18)}}的其他基金
State Medical Cannabis Laws, Chronic Pain, and Opioids: A Mixed-Methods Approach
州医用大麻法、慢性疼痛和阿片类药物:混合方法
- 批准号:
10199994 - 财政年份:2020
- 资助金额:
$ 58.61万 - 项目类别:
STATE MEDICAL CANNABIS LAWS, CHRONIC PAIN, AND OPIOIDS: A MIXED-METHODS APPROACH
国家医用大麻法、慢性疼痛和阿片类药物:混合方法
- 批准号:
10748731 - 财政年份:2020
- 资助金额:
$ 58.61万 - 项目类别:
State Medical Cannabis Laws, Chronic Pain, and Opioids: A Mixed-Methods Approach
州医用大麻法、慢性疼痛和阿片类药物:混合方法
- 批准号:
10392504 - 财政年份:2020
- 资助金额:
$ 58.61万 - 项目类别:
Using an innovative quality improvement process to increase delivery of evidenced-based CVD risk factor care in community mental health organizations
使用创新的质量改进流程来增加社区精神卫生组织中基于证据的 CVD 危险因素护理的提供
- 批准号:
10188641 - 财政年份:2018
- 资助金额:
$ 58.61万 - 项目类别:
Mental Health Services and Systems Training Program
心理健康服务和系统培训计划
- 批准号:
10187652 - 财政年份:2017
- 资助金额:
$ 58.61万 - 项目类别:
An Evaluation of State Laws Intended to Curb High-Risk Opioid Prescribing
对旨在遏制高风险阿片类药物处方的州法律的评估
- 批准号:
9421929 - 财政年份:2017
- 资助金额:
$ 58.61万 - 项目类别:
Improving Evidence-based Behavioral, Somatic and Social Service Delivery for SMI
改善 SMI 的循证行为、躯体和社会服务交付
- 批准号:
9032165 - 财政年份:2015
- 资助金额:
$ 58.61万 - 项目类别:
Improving Evidence-based Behavioral, Somatic and Social Service Delivery for SMI
改善 SMI 的循证行为、躯体和社会服务交付
- 批准号:
9144866 - 财政年份:2015
- 资助金额:
$ 58.61万 - 项目类别:
Improving Evidence-based Behavioral, Somatic and Social Service Delivery for SMI
改善 SMI 的循证行为、躯体和社会服务交付
- 批准号:
9339398 - 财政年份:2015
- 资助金额:
$ 58.61万 - 项目类别:
Using an innovative quality improvement process to increase delivery of evidenced-based CVD risk factor care in community mental health organizations
使用创新的质量改进流程来增加社区精神卫生组织中基于证据的 CVD 危险因素护理的提供
- 批准号:
9762201 - 财政年份:
- 资助金额:
$ 58.61万 - 项目类别:
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