Center for Appalachian Research in Environmental Sciences-Integrated Health Sciences Facility Core (IHSFC)

阿巴拉契亚环境科学研究中心-综合健康科学设施核心 (IHSFC)

• 批准号: 10610033
• 负责人: John Anthony Bauer
• 金额: $ 22.95万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-05-01 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10610033
• 关键词: Address; Analytical Chemistry; Appalachian Region; Area; Back; Categories; Clinical; Clinical Data; Clinical Research; Clinical Sciences; Collaborations; Communication; Communication Research; Communities; Consultations; Core Facility; Data; Data Analyses; Data Science; Development; Dimensions; Disasters; Educational workshop; Elements; Environmental Exposure; Environmental Health; Environmental Science; Evaluation; Fostering; Funding; Goals; Growth; Health; Health Sciences; Human; Infrastructure; Institution; Institutional Review Boards; Integrative Medicine; Kentucky; Laboratories; Leadership; Link; Methodology; Methods; Modeling; Molecular Toxicology; National Institute of Environmental Health Sciences; Output; Patients; Peer Review; Pilot Projects; Policy Maker; Process; Program Development; Public Health; Public Health Practice; Publishing; Reporting; Research; Research Activity; Research Methodology; Research Personnel; Research Project Grants; Research Support; Resources; Review Literature; Role; Sampling; Science; Scientist; Services; Statistical Data Interpretation; Strategic Planning; Structure; Testing; Toxicology; Training; Translational Research; Universities; Water; Work; biobank; career development; clinical practice; cohort; community building; community engagement; community partnership; data management; health assessment; health communication; health science research; health training; high risk; improved; innovation; meetings; member; multidisciplinary; novel; novel strategies; operation; prevent; repository; response; service coordination; success; translational health science; translational impact; translational pipeline; waterborne

PROJECT SUMMARY – Integrative Health Sciences Facility Core The University of Kentucky Center for Appalachian Research in Environmental Sciences (UK-CARES) Integrated Health Sciences Facility Core (IHSFC) will facilitate translational research in environmental health science (EHS), ranging from basic, clinical, exposure assessment, and communication research, to support and sustain collaborative, multidisciplinary connections, and academic-community partnerships. A key element of the IHSFC is the formation of four EHS translational research hubs: 1-Molecular Toxicology; 2-Clinical Research and Data Sciences; 3-Community Exposure Assessment; and 4-Environmental Health Communication. Each hub will provide content expertise, support, and access to EHS methodologies and services, and facilitate project development across the translational research spectrum. The hub structure will enhance disciplinary diversity within the IHSFC and support campus-wide integration and cross-Center communication. The IHSFC will build on our record of early success, refining our operational model and targeting new partnerships among Center members while providing expert consultation, translational research support, and team building strategies across the Center’s re-aligned science themes: (a) Health Impacts of Waterborne Contaminants (WATER); (b) Health Impacts of Indoor and Outdoor Airborne Contaminants (AIR); and (c) Emerging Environmental Health Threats (EMERGING THREATS). Specifically, the IHSFC aims to 1) provide access to EHS research services, 2) deliver EHS project support, and 3) enhance translational research partnerships. First, the IHSFC Research Support Portal will direct the flow of investigator requests to IHSFC staff and relevant hub leaders who will link Center members to the appropriate cores (e.g., Analytical Chemistry Core for Environmental Sciences and Community Engagement Core) and resources (e.g., data management and statistical analysis) for project facilitation. The Portal will facilitate coordination, prioritization, tracking, and use of facility core services, Center-wide. Second, IHSFC hub leaders will provide EHS best practices workshops and training sessions in collaboration with the Career Development Program. Third, we will establish Rapid Response Teams, comprised of the hub leaders and other Center members, to promote research translation and partnerships, enabling prompt responses to community identified EHS threats and new exposures. The IHSFC will fulfill the need for a centralized and accessible core that supports multidirectional EHS research activities within the Center, across UK campus, with community investigators, and with other EHS Core Centers, providing timely consultation and support for an impactful portfolio of EHS research projects, while fostering a highly collaborative institutional EHS culture. The IHSFC will expand expertise and services, enhancing the core’s central role in daily UK-CARES operations, and provide the infrastructure to facilitate the progression and expansion of EHS from fundamental questions into testing, clinical practice, and public health impact to improve public health and clinical practice in environmental health.

项目概要-综合健康科学设施核心 肯塔基州大学阿巴拉契亚环境科学研究中心（UK-CARES） 综合健康科学设施核心（IHSFC）将促进环境健康的转化研究 科学（EHS），从基础，临床，暴露评估和通信研究，以支持 并保持协作，多学科的连接，和学术界的伙伴关系。一个关键因素 IHSFC成立了四个EHS转化研究中心：1-分子毒理学; 2-临床 研究和数据科学; 3-社区接触评估; 4-环境健康 通信每个中心将提供内容专业知识、支持以及对EHS方法的访问， 服务，并促进整个转化研究领域的项目开发。枢纽结构将 加强IHSFC内的学科多样性，并支持校园范围内的整合和跨中心 通信IHSFC将在我们早期成功的基础上，完善我们的运营模式， 针对中心成员之间的新伙伴关系，同时提供专家咨询， 支持和团队建设战略，贯穿中心重新调整的科学主题：（a） （B）室内和室外空气传播污染物对健康的影响; （c）新出现的环境健康威胁。具体而言，IHSFC的目标是：1） 提供EHS研究服务，2）提供EHS项目支持，3）加强翻译 研究伙伴关系。首先，IHSFC研究支持门户网站将引导研究者请求流向 IHSFC工作人员和相关中心领导人将中心成员与适当的核心联系起来（例如，分析 环境科学化学核心和社区参与核心）和资源（例如，数据 管理和统计分析），以促进项目。门户网站将促进协调、确定优先次序， 跟踪和使用中心范围内的设施核心服务。第二，IHSFC枢纽领导者将提供最好的EHS 与职业发展方案合作举办实践讲习班和培训班。三是 将建立由中心领导和其他中心成员组成的快速反应小组，以促进 研究翻译和合作伙伴关系，使社区能够迅速响应确定的EHS威胁， 新的曝光。IHSFC将满足对集中式和可访问核心的需求， 在中心内，在英国校园内，与社区调查人员一起开展多方向的EHS研究活动， 并与其他EHS核心中心合作，为有效的EHS产品组合提供及时的咨询和支持 研究项目，同时培养高度协作的机构EHS文化。IHSFC将扩大 专业知识和服务，加强核心在日常UK-CARES业务中的核心作用，并提供 促进EHS从基本问题到测试的发展和扩展的基础设施， 临床实践和公共卫生的影响，以改善公共卫生和环境卫生的临床实践。