NRG Oncology Network Group Operations Center

NRG 肿瘤网络集团运营中心

• 批准号: 10609465
• 负责人: NORMAN WOLMARK
• 金额: $ 416.94万
• 依托单位: NRG ONCOLOGY FOUNDATION, INC.
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-17 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10609465
• 关键词: Advocate; Amendment; Attention; Cancer Therapy Evaluation Program; Clinical Trials; Clinical Trials Data Monitoring Committees; Committee Members; Complex; Data Coordinating Center; Development; Disease; Goals; Infrastructure; Institution; International; Knowledge; Leadership; Malignant Neoplasms; Mentorship; Mission; Multi-Institutional Clinical Trial; Oncology; Oncology Group; Patients; Phase; Physicians; Program Development; Publications; Regulatory Affairs; Research; Research Activity; Research Personnel; Safety; Site; Support Groups; Translational trial; Work; design; experience; investigator training; member; operation; programs; prospective; protocol development; statistics; success

NRG Clinical Trials Development Core Abstract The NRG Oncology (NRG) Clinical Trials Development Core (Core) provides the scientific leadership and infrastructure necessary to support the group's research activities and initiatives. NRG has a robust facility for clinical trials development, led by physician-investigators, statisticians, and administrative directors who possess an outstanding quantity and quality of knowledge and expertise in designing and directing complex, multicenter clinical trials that reflect the specific aims of the group. The Core works closely with the NRG's Statistics and Data Management Center, the NRG Data Monitoring Committee (DMC), and the NRG Administrative Core in soliciting, reviewing, approving, and developing prospective clinical trials. The program is committed to developing clinical trials that are congruent with NRG's and NCI's mission to implement high-quality clinical and translational trials (primarily late phase trials) in a timely manner. To that end, the Core investigators and staff work closely with NCI-CTEP, the NCTN's centralized functions (e.g., CTSU, CIRB) and the other NCTN Groups. Patient advocates and attention to diversity are included in the Core's functions. NRG's clinical trials development program is led by its Research Strategy Committee, whose members are internationally recognized chairs and vice-chairs of NRG's cancer disease site and other scientific committees who have great experience in institutional and network group research. The leaders and core members of these committees understand the importance of protocol development, new investigator training/mentorship, trial conduct, completion and timely analysis and publication of study results. These physician investigators and the Core administrative staff are well aligned with the overall mission of the NCTN and the continued success of NRG Oncology.

NRG临床试验开发核心摘要 NRG肿瘤学(NRG)临床试验开发核心(CORE)提供科学 支持集团的研究活动和倡议所需的领导力和基础设施。 NRG拥有强大的临床试验开发设施，由医生和研究人员领导， 具有杰出数量和质量的统计员和行政总监 在设计和指导复杂的多中心临床试验方面的知识和专业知识 反映小组的具体目标。核心与NRG的统计和 数据管理中心、NRG数据监控委员会(DMC)和NRG 在征集、审查、批准和开发前瞻性临床试验方面的行政核心。 该计划致力于开发与NRG和NCI一致的临床试验 实施高质量临床和转化性试验(主要是晚期试验)的使命 及时地。为此，核心调查员和工作人员与NCI-CTEP、 NCTN的集中职能(如CTSU、CIRB)和其他NCTN小组。有耐心的 核心的职能包括倡导和关注多样性。NRG的临床试验 发展计划由其研究战略委员会领导，该委员会的成员是 国际公认的NRG癌症疾病网站主席和副主席以及其他 在机构和网络小组研究方面拥有丰富经验的科学委员会。 这些委员会的领导人和核心成员明白礼仪的重要性。 开发、新调查员培训/指导、试验进行、完成和及时分析 和研究结果的出版。这些内科调查员和核心行政人员 与NCTN的总体使命和NRG的持续成功保持良好的一致性 肿瘤学。