NRG Oncology Network Group Operations Center

NRG 肿瘤网络集团运营中心

• 批准号: 10910261
• 负责人: NORMAN WOLMARK
• 金额: $ 10.75万
• 依托单位: NRG ONCOLOGY FOUNDATION, INC.
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-17 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10910261
• 关键词: Adolescent and Young Adult; African ancestry; Alaska Native; American; Clinical Research; Communication; Country; Credentialing; Discipline of Nursing; Disease; Enrollment; General Population; Grant; Guidelines; Hispanic; Image; Institution; Latino; Malignant Neoplasms; Mission; Monitor; Monitoring Clinical Trials; National Clinical Trials Network; Native Americans; Native Hawaiian; Oncology; Pacific Islander; Patients; Performance; Process; Protocols documentation; Puerto Rico; Qualifying; Radiation Oncology; Radiation therapy; Review Committee; Science; Site; Time; Translational Research; Underrepresented Populations; Update; Washington; base; data quality; health disparity; improved; innovation; member; operation; participant enrollment; programs; quality assurance; rare cancer

Member Site Core Abstract NRG Oncology (NRG) has established a large and diverse membership that includes 220 Tier 1 (Main Members) and 1188 Tier 2 enrolling sites. NRG Main Members and affiliates are located in all 50 states, Washington, DC, and Puerto Rico. There are 16 Canadian Main Members and 12 Non-North American Main Members located in 8 countries. NRG Oncology has the largest membership base of the groups in the NCI National Clinical Trials Network (NCTN), and NRG members also contribute the highest percentage of patients to the NCTN. For the period of March 1, 2014, through August 31, 2017, NRG trial accrual plus accrual to other NCTN group trials credited to NRG by its members represents approximately a third of the total NCTN accrual for that grant period. Of the 9,000 American patients enrolled on NRG trials during this time period, 12.7% self-identified as of African descent, 8.0% as Hispanic or Latino, and 1.3% as Native Hawaiian, other Pacific Islander, Native American, or Alaska native.. NRG has developed an audit program which is in compliance with the guidelines established by the NCI's Clinical Trials Monitoring Branch (CTMB). In addition, NRG carefully evaluates protocol accrual and data quality, a practice which enables the group to identify and intervene when underperforming centers are identified. NRG has developed a variety of accrual enhancement efforts including: the NRG Protocol Support Committee that reviews all proposed protocols relative to nursing and non-nursing matters; the NRG Health Disparities Committee whose primary aim is to increase enrollment of underrepresented populations to NRG trials; the Communications Committee which provides updates to the NRG members and general public promoting NRG activities and trials; the Center for Innovation in Radiation Oncology (CIRO) which assists NRG members with radiotherapy and imaging quality assurance process, including site qualification, credentialing and case reviews; and a Toll-Free 800 Line available for NRG members to obtain answers to protocol related questions. NRG cancer disease site committees have developed successful programs for patients with rare tumors and trials that provide an opportunity to enroll adolescent and young adult patients.

会员网站核心摘要 NRG肿瘤学(NRG)已经建立了一个庞大和多样化的成员，其中包括220个Tier 1 (主要会员)和1188个二级招生网站。NRG主要成员和附属机构位于 在所有50个州，华盛顿特区和波多黎各。加拿大有16个主要成员和 12个非北美主要成员，分布在8个国家。NRG肿瘤学拥有最大的 NCI国家临床试验网络(NCTN)和NRG中小组的成员基础 成员也为NCTN贡献了最高比例的患者。在……期间 2014年3月1日至2017年8月31日，NRG试用计提加上对其他NCTN小组的计提 NRG成员归功于NRG的试验约占NCTN总数的三分之一 该授权期的应计费用。在此期间登记参加NRG试验的9000名美国患者中 在同一时期，12.7%的人认为自己是非洲裔，8.0%的人认为是西班牙裔或拉丁裔，1.3%的人认为自己是非洲人后裔 作为夏威夷原住民、其他太平洋岛民、美洲原住民或阿拉斯加原住民。NRG有 制定了符合NCI制定的指导方针的审计计划 临床试验监测处(CTMB)。此外，NRG仔细评估协议应计费用 和数据质量，这是一种做法，使该组织能够识别和干预何时 确定了表现不佳的中心。NRG已经开发了各种应计利润增加 工作包括：审查所有拟议议定书的NRG议定书支助委员会 关于护理和非护理事项；NRG健康差距委员会，其 主要目标是增加NRG试验中代表性不足的人群的登记人数； 向NRG成员和公众提供最新信息的传播委员会 促进NRG活动和试验；放射肿瘤学创新中心(CERO) 它帮助NRG成员进行放射治疗和成像质量保证过程， 包括现场资格、认证和案例审查；以及免费拨打的800电话 供NRG成员获取与礼仪相关的问题的答案。NRG癌症病区 委员会为罕见肿瘤患者制定了成功的计划，并进行了试验 提供机会招收青少年和青壮年患者。