Training Program in Immunology and Inflammation

免疫学和炎症培训计划

• 批准号: 10610333
• 负责人: Susan Ruth Schwab
• 金额: $ 37.42万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10610333
• 关键词: Immunology; Inflammation; Training Programs

ABSTRACT The Immunology and Inflammation training program at NYU Grossman School of Medicine (NYUGSoM) provides excellent pre-doctoral and post-doctoral training at the interface between immunology and human disease. The program trains students and postdoctoral fellows in basic immunology as well as its applications in host-pathogen interactions, autoimmune and inflammatory diseases, and anti-tumor immunity. Innovative courses provide trainees with a foundation in the field and training in critical evaluation of data, and the students build on this foundation in the weekly immunology seminar series and journal club. Trainees develop their writing and presentation skills through participation in work-in- progress presentations, journal clubs, and an annual retreat. A critical element of training is research experience, and the training program currently has 30 faculty who are highly productive scientists with extensive mentoring experience. In addition, NYUGSoM is undertaking a major expansion of its immunology research base. The first two cycles of the program supported many highly successful trainees, and we propose to build on this success with a training program with 4 pre-doctoral and 2 post- doctoral positions. The long-term goal of the program is to train a new cadre of rigorous and creative researchers in the broad and interdisciplinary area of immunology and its relation to inflammatory processes. The successful trainees will be ideally positioned to contribute to the development of novel therapies to treat inflammatory diseases.

摘要 纽约大学格罗斯曼医学院（NYUGSoM）的免疫学和炎症培训计划 在免疫学和免疫学之间的接口提供优秀的博士前和博士后培训， 人类疾病该计划培养学生和博士后研究员在基础免疫学以及其 在宿主-病原体相互作用、自身免疫和炎性疾病以及抗肿瘤中的应用 免疫力创新课程为学员提供实地基础和关键技能培训， 评估数据，学生在每周免疫学系列研讨会上建立在此基础上 日记俱乐部学员通过参加工作， 进展报告、期刊俱乐部和年度务虚会。培训的一个关键要素是研究 经验，培训计划目前有30名教师谁是高产科学家， 丰富的指导经验。此外，NYUGSoM正在进行其 免疫学研究基地。该计划的前两个周期支持了许多非常成功的 学员，我们建议建立在这一成功的培训计划与4博士前和2博士后， 博士职位。该计划的长期目标是培养一个新的干部严谨和创造性 免疫学及其与炎症的关系的广泛和跨学科领域的研究人员 流程.成功的学员将被理想地定位为促进小说的发展， 治疗炎症性疾病的疗法。

项目成果

Prevalence of IgG Autoantibodies against GD3 Ganglioside in Acute Zika Virus Infection.

• DOI: 10.3389/fmed.2018.00025
• 发表时间: 2018
• 期刊: Frontiers in medicine
• 影响因子: 3.9
• 作者: Nico D;Conde L;Rivera-Correa JL;Vasconcelos-Dos-Santos A;Mesentier-Louro L;Freire-de-Lima L;Arruda MB;Freire-de-Lima CG;Ferreira ODC Jr;Lopes Moreira ME;Zin AA;Vasconcelos ZFM;Otero RM;Palatnik-de-Sousa CB;Tanuri A;Todeschini AR;Savino W;Rodriguez A;Morrot A
• 通讯作者: Morrot A

Mononuclear cell dynamics in M. tuberculosis infection provide opportunities for therapeutic intervention.

结核分枝杆菌感染中的单核细胞动力学为治疗干预提供了机会。

• DOI: 10.1371/journal.ppat.1007154
• 发表时间: 2018-10
• 期刊: PLoS pathogens
• 影响因子: 6.7
• 作者: Norris BA;Ernst JD
• 通讯作者: Ernst JD

Genetic suppression of inflammation blocks the tumor-promoting effects of TGF-β in gastric tissue.

• DOI: 10.1158/0008-5472.can-13-3404
• 发表时间: 2014-05-01
• 期刊: Cancer research
• 影响因子: 11.2
• 作者: Ota M;Horiguchi M;Fang V;Shibahara K;Kadota K;Loomis C;Cammer M;Rifkin DB
• 通讯作者: Rifkin DB

Combination Immunotherapy: Taking Cancer Vaccines to the Next Level.

• DOI: 10.3389/fimmu.2018.00610
• 发表时间: 2018
• 期刊: Frontiers in immunology
• 影响因子: 7.3
• 作者: Grenier JM;Yeung ST;Khanna KM
• 通讯作者: Khanna KM

Hierarchy of human IgG recognition within the Staphylococcus aureus immunome.

金黄色葡萄球菌免疫组中人类 IgG 识别的层次结构。

• DOI: 10.1038/s41598-018-31424-3
• 发表时间: 2018
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Radke,EmilyE;Brown,StuartM;Pelzek,AdamJ;Fulmer,Yi;Hernandez,DavidN;Torres,VictorJ;Thomsen,IsaacP;Chiang,WilliamK;Miller,AndyO;Shopsin,Bo;Silverman,GreggJ
• 通讯作者: Silverman,GreggJ