Center for Clinical and Translational Science and Training

临床和转化科学与培训中心

• 批准号: 10613549
• 负责人: JESSICA A KAHN
• 金额: $ 452.02万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10613549
• 关键词: Abbreviations; Address; Adult; Area; Award; Basic Science; Biometry; Body mass index; Center for Translational Science Activities; Child; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Data; Data Science; Development; Dissemination and Implementation; Education; Educational process of instructing; Elderly; Environment; Epidemiology; Ethics; Ethnic Origin; Family; Foundations; Gender; Genomics; Goals; Grant; Health; Health system; Healthcare; Individual; Informatics; Information Technology; Institution; Knowledge; Learning; Longevity; Measurable; Medical center; Medicine; Methodology; Methods; Mission; Outcome; Participant; Patient Care; Patient Recruitments; Patients; Pediatric Hospitals; Population; Provider; Race; Research; Research Design; Research Personnel; Resources; Science; Site; Special Population; System; Time; Training; Translating; Translational Research; Translations; Underrepresented Minority; Universities; Workforce Development; biomedical informatics; clinical center; clinical implementation; college; community engagement; data infrastructure; data management; disparity reduction; drug development; empowerment; experience; health care delivery; health disparity; health outcome disparity; improved; innovation; learning community; medical specialties; member; metropolitan; multidisciplinary; novel; population health; practice-based research network; programs; pyrolytic carbon; recruit; research to practice; success; synergism; technology development; translational engagement; translational pipeline; translational scientist

Contact PD/PI: Heubi, James E OVERALL ABSTRACT The Center for Clinical and Translational Science and Training (CCTST) was established at the University of Cincinnati (UC) in 2005 and awarded an institutional Clinical and Translational Science Award (CTSA) in 2009. Since that time, basic science research, genomics, technology, and drug development have made remarkable progress, warranting new solutions for translating research to practice. Concurrent with these discoveries, the CCTST has created innovative solutions for our program functions, including biomedical informatics, biostatistics and study design, regulatory and ethics, community engagement and team science, recruitment and support for clinical trials, patient care interactions, pilot grants, and translational workforce development. With the competitive renewal application and the current revision and creation of CCTST 3.0, we will continue to utilize the guiding principles of learning health systems to develop stronger bidirectional relationships with our community and expeditiously bring discoveries to application. Indeed, we intend to capture this tremendous opportunity to better align the clinical/operational mission of the health system with the research mission of the University and its affiliates. The overarching goal of the CCTST is to maximize the impact of clinical and translational research to improve individual and population health locally and nationally, through 1) engaging stakeholders to collaboratively translate research into improved health care practice and community wellness across the lifespan; 2) developing a diverse, multidisciplinary workforce to conduct innovative, team-based, community-engaged translational research and to disseminate and implement findings that will improve health outcomes and reduce disparities; and 3) optimizing the use of biomedical data across the translational research continuum using innovative data science methods to advance discovery, dissemination, and implementation. For each of the programs and optional functions, these aims serve as the basis for planned innovative activities and to facilitate cross-core integration. We specifically target learning health systems as an optional module for this application because of the expertise available at Cincinnati Children's Hospital Medical Center that can be leveraged across the CCTST and its health care affiliates. In fulfilling these aims, CCTST 3.0 will catalyze the translation of discoveries into improved health outcomes locally and nationally. Page 307 Project Summary/Abstract Contact PD/PI: Heubi, James E NARRATIVE The CTSA consortium has matured to the point that 57 sites are working together to advance science with the goal to improve the health of the nation. The University of Cincinnati Center for Clinical and Translational Science and Training has become a portal of entry for clinical and translational investigators to obtain support for the completion of their studies across the spectrum of translational science, from the bench to population health. With this revised renewal application, we will develop additional innovative methods to produce high quality research, share these discoveries, collaborate with other CTSA hubs, and have a measurable impact on the health of our community using the principles of a learning health system. Page 308

联络PD/PI: Heubi， James E