Sheltered Outdoor Housing Expansion for the TNPRC SPF Rhesus Macaque Breeding Colony
TNPRC SPF 恒河猴繁殖地的庇护室外房屋扩建
基本信息
- 批准号:10588719
- 负责人:
- 金额:$ 649.98万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-16 至 2027-05-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAnimal ExperimentationAnimalsApplied ResearchAreaBasic ScienceBiomedical ResearchBreedingCensusesComplementEnsureEvaluationFacultyFundingFutureHealthHousingHumanInfrastructureInstitutionKnowledgeMacacaMacaca mulattaPersonal SatisfactionPrimatesProductionRecommendationReportingResearchResearch PersonnelResearch PriorityResourcesScientific Advances and AccomplishmentsUnited States National Institutes of HealthUniversitiesWeatherdesignflexibilitygerm free conditionimprovednonhuman primatenoveloperationprograms
项目摘要
PROJECT SUMMARY / ABSTRACT
The Tulane National Primate Research Center (TNPRC) of Tulane University is one of seven National Primate
Research Centers (NPRC) sponsored by the National Institutes of Health. The Center is dedicated to providing
the infrastructure and support for basic and applied research efforts to advance scientific knowledge and improve
human and animal health and well-being. The NPRC program provides resources and opportunities for research
using nonhuman primates (NHP) to core faculty and faculty affiliated with outside institutions. The TNPRC
specific pathogen free (SPF) rhesus macaque breeding colony is among the largest in the NPRC program, with
a census of approximately 5,000. Over the past 5 years, the TNPRC SPF breeding colonies have supplied 2,099
animals for research programs of core and affiliate investigators across the US. There continues to be high
national demand for SPF rhesus macaques which cannot be met by current NPRC breeding operations. In 2018,
the NIH sponsored the NHP Evaluation and Analysis Project to enhance understanding of the demand for and
supply of NHP within the US. Key recommendations made to ensure the adequate supply of NHPs for biomedical
research included improving infrastructure and providing support for SPF NHP breeding colony expansion. Since
the results of the 2018 report were made public, the TNPRC has undertaken assessments to identify the needs
of the program to expand its SPF rhesus macaque breeding colony. Along with funding from the NIH, the TNPRC
has committed funds and initiated projects to: 1) improve the breeding colony management program and 2)
expand infrastructure to meet the current and projected future national demand. Principal components of the
long-term plan for infrastructure improvement are to increase the number of indoor/outdoor housing
configurations for added protection of NHP from inclement weather and complement the existing outdoor NHP
housing enclosures. Funding is requested to construct indoor/outdoor enclosures located on the breeding colony
campus for the purpose of housing and breeding SPF rhesus macaques. This project will add facilities to support
our commitment to expand production of SPF rhesus macaques used for NIH-established priority research areas
at the TNPRC and nationally. The facilities have been designed in alignment with our long-term infrastructure
improvement plan to enhance protection of animals, increase housing capacity and flexibility, and provide novel
and proven environmental enhancement components. The animals produced as a result of this infrastructure
improvement project will help address the national shortage of SPF macaques.
项目摘要/摘要
杜兰大学国家灵长类研究中心(TNPRC)是七个国家灵长类之一
研究中心(NPRC)由美国国立卫生研究院赞助。该中心致力于提供
基础设施和对基础研究和应用研究的支持,以促进科学知识和改进
人类和动物的健康和福祉。NPRC计划为研究提供资源和机会
使用非人类灵长类动物(NHP)为核心教员和附属于外部机构的教员。TNPRC
无特定病原体(SPF)猕猴繁殖群体是NPRC计划中最大的群体之一,有
大约5000人的人口普查。在过去的5年里,TNPRC SPF繁殖群体提供了2099个
为全美核心和附属调查人员的研究项目提供动物。持续高企
国家对SPF猕猴的需求,目前NPRC的饲养行动无法满足这一需求。2018年,
国家卫生研究院赞助了国家卫生计划评估和分析项目,以加强对国家卫生计划需求的了解和
美国国内的NHP供应。为确保生物医学用NHP的充足供应而提出的主要建议
研究包括改善基础设施和为SPF NHP育种群体扩张提供支持。自.以来
2018年报告结果公布,TNPRC已进行评估,以确定需求
扩大其SPF恒河猴繁殖群体的计划。除了来自国家卫生研究院的资金外,TNPRC
已承诺提供资金并发起以下项目:1)改善繁殖群体管理计划;2)
扩大基础设施,以满足当前和预测的未来国家需求。主成分股
改善基础设施的长期计划是增加室内/室外住房的数量
用于增加NHP免受恶劣天气影响的配置,并补充现有的室外NHP
住房封闭物。需要资金来建造位于繁殖地的室内/室外围栏。
校园内以饲养SPF级恒河猴为目的。该项目将增加设施以支持
我们承诺扩大SPF猕猴的生产,用于NIH-确立的优先研究领域
在TNPRC和全国范围内。这些设施的设计与我们的长期基础设施保持一致。
改善计划,以加强对动物的保护,增加住房容量和灵活性,并提供新颖的
和经过验证的环境增强组件。由于这种基础设施而产生的动物
改进项目将有助于解决全国SPF猕猴短缺的问题。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
KASI E RUSSELL-LODRIGUE其他文献
KASI E RUSSELL-LODRIGUE的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('KASI E RUSSELL-LODRIGUE', 18)}}的其他基金
Tulane National Primate Research Center AIDS SPF Breeding Colony Maintenance
杜兰国家灵长类研究中心 AIDS SPF 繁殖群体维护
- 批准号:
10651840 - 财政年份:2017
- 资助金额:
$ 649.98万 - 项目类别:
Maintenance of an SPF Macaque Breeding Colony for AIDS Research
维持 SPF 猕猴繁殖群以进行艾滋病研究
- 批准号:
10549735 - 财政年份:2001
- 资助金额:
$ 649.98万 - 项目类别:
Maintenance of an SPF Macaque Breeding Colony for AIDS Research
维持 SPF 猕猴繁殖群以进行艾滋病研究
- 批准号:
10808548 - 财政年份:2001
- 资助金额:
$ 649.98万 - 项目类别:
相似海外基金
Development of a Drosophila-based platform to replace and reduce animal experimentation in epilepsy research
开发基于果蝇的平台来取代和减少癫痫研究中的动物实验
- 批准号:
NC/V001051/1 - 财政年份:2020
- 资助金额:
$ 649.98万 - 项目类别:
Research Grant
Doctoral Dissertation Research: Ethical Issues in Animal Experimentation
博士论文研究:动物实验的伦理问题
- 批准号:
1424484 - 财政年份:2014
- 资助金额:
$ 649.98万 - 项目类别:
Standard Grant
Tissue formation involving stem/progenitor cell research and animal experimentation (N01)
涉及干/祖细胞研究和动物实验的组织形成(N01)
- 批准号:
30245585 - 财政年份:2006
- 资助金额:
$ 649.98万 - 项目类别:
Collaborative Research Centres
Animal Experimentation system as an infrastructure to support translational progression of diabetes research to medical practice
动物实验系统作为支持糖尿病研究向医学实践转化的基础设施
- 批准号:
17200029 - 财政年份:2005
- 资助金额:
$ 649.98万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Animal experimentation and cardiac phenotyping of transgenic mouse models
转基因小鼠模型的动物实验和心脏表型分析
- 批准号:
13327687 - 财政年份:2005
- 资助金额:
$ 649.98万 - 项目类别:
Research Units














{{item.name}}会员




