Wright Regional Center for Clinical and Translational Science

赖特临床和转化科学区域中心

• 批准号: 10617079
• 负责人: FREDERICK Gerard MOELLER
• 金额: $ 402.34万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2030-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10617079
• 关键词: Address; Affect; Agreement; All of Us Research Program; Ambulatory Care; COVID-19; COVID-19 pandemic; Clinical Research; Clinical Sciences; Collaborations; Communities; Data; Endowment; Epidemic; Equity; Ethnic Population; Faculty; Fostering; Funding; Goals; Health; Health Personnel; Historically Black Colleges and Universities; Housing; Informatics; Infrastructure; Institution; Leadership; Low income; Machine Learning; Maps; Methods; North Carolina; Outcome; Outcomes Research; Patients; Population Heterogeneity; Process; Protocols documentation; Research; Rural; Spottings; Techniques; Training; Translational Research; United States National Institutes of Health; Universities; Virginia; Work; Workforce Development; biomedical imaging; clinical center; community engaged research; community engagement; data interoperability; ethnic minority population; health difference; health disparity; health equity; health equity promotion; improved; innovation; machine learning method; medical schools; member; opioid overdose; participant enrollment; patient population; practice-based research network; programs; racial minority population; racial population; recruit; rural patients; telehealth; timeline; tool; vulnerable community

Building on the VCU C. Kenneth and Dianne Wright Center for Clinical and Translational Research and its research endowment, the Wright Regional Center for Clinical and Translational Science (Wright Regional CCTS) is a collaboration of partner institutions that serves regions of Virginia and North Carolina, including Eastern Virginia Medical School, a community focused medical school in Norfolk, Virginia with a strong community engaged research program in low income housing; Old Dominion University, a diverse public university in Norfolk Virginia with strengths in machine learning and AI techniques for biomedical data; Virginia Commonwealth University, a public university in Richmond, Virginia which has been a CTSA hub since 2010, with strengths in community engaged research; and Virginia State University, a Historically Black College and University with expertise to advance workforce diversity. The Overall Objective of the Wright Regional CCTS is to advance health equity through actively engaging diverse communities, training a diverse research workforce, and supporting the rapid implementation of innovative clinical and translational science (CTS) with our partners and collaborators and throughout the CTSA program. This will be carried out though the following Specific Aims: Aim 1: Enhance translational research workforce development with a focus on diversity to ultimately enhance recruitment of diverse patient populations into clinical research. Aim 2: Use health outcomes data to develop tools and methods to document differences in health outcomes within the community to support the goal of achieving health equity. Aim 3: Promote protocol review and oversight to enhance the quality of clinical research and reduce the timeline for regulatory approval. Aim 4: Work together across partner and collaborator institutions to use informatics data and tools to promote interoperability of data for high impact clinical research. Aim 5: Build on our existing community engagement and telehealth infrastructure to enhance recruitment of hard-to-reach low income and rural patient populations into clinical research. Impact: The Wright Regional CCTS will build on our strengths in community engaged research to support innovative translational science tools to address health equity in collaboration with our partners and community. We will enhance the diversity and rural impact of our translational research workforce, extend protocol review and oversight processes to improve the quality and efficiency of clinical research, develop innovative methods to engaged hard to reach low-income and rural patient populations in clinical research, and disseminate and implement successful CTS programs in our community and across the CTSA network.

建立在VCU C. Kenneth和Dianne Wright临床和转化研究中心及其 研究捐赠基金，赖特临床和转化科学区域中心（Wright Regional CCTS） 是为弗吉尼亚州和北卡罗来纳州地区提供服务的合作伙伴机构的合作 弗吉尼亚医学院，弗吉尼亚州诺福克市的一所社区医学院，有一个强大的社区 低收入住房的研究计划；旧多米尼翁大学，一所多元化的公立大学 诺福克弗吉尼亚州具有机器学习和生物医学数据的AI技术的优势；弗吉尼亚 英联邦大学，弗吉尼亚州里士满的一所公立大学，自2010年以来一直是CTSA枢纽 具有社区参与研究的优势；弗吉尼亚州立大学，一所历史悠久的黑人学院， 具有专业知识的大学，以提高员工多样性。 赖特地区CCT的总体目标是通过积极的 吸引各种社区，培训多样化的研究人员并支持快速 与我们的合作伙伴和合作者实施创新的临床和转化科学（CTS） 以及整个CTSA计划。 这将通过以下特定目的进行： 目标1：增强转化研究劳动力发展，重点是多样性 将各种患者人群招募到临床研究中。 目标2：使用健康结果数据来开发工具和方法来记录健康的差异 社区内的成果支持实现健康公平的目标。 目标3：促进协议审查和监督以提高临床研究的质量并减少 监管批准的时间表。 目标4：跨合作伙伴和合作机构一起使用信息学数据和工具来合作 促进数据的互操作性，以进行高影响临床研究。 目标5：建立在我们现有的社区参与和远程医疗基础设施的基础上，以增强招聘 难以到达的低收入和农村患者人群进入临床研究。 影响：赖特地区CCT将基于我们在社区参与研究中的优势以支持 与我们的合作伙伴和社区合作解决健康公平的创新转化科学工具。 我们将增强转化研究人员的多样性和农村影响，扩展协议审查 和监督过程以提高临床研究的质量和效率，开发创新方法 在临床研究中，努力参与到低收入和农村患者人群，并进行传播和 在我们的社区和CTSA网络中实施成功的CTS程序。