Wright Regional Center for Clinical and Translational Science

赖特临床和转化科学区域中心

• 批准号: 10617079
• 负责人: FREDERICK Gerard MOELLER
• 金额: $ 402.34万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2030-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10617079
• 关键词: Address; Affect; Agreement; All of Us Research Program; Ambulatory Care; COVID-19; COVID-19 pandemic; Clinical Research; Clinical Sciences; Collaborations; Communities; Data; Endowment; Epidemic; Equity; Ethnic Population; Faculty; Fostering; Funding; Goals; Health; Health Personnel; Historically Black Colleges and Universities; Housing; Informatics; Infrastructure; Institution; Leadership; Low income; Machine Learning; Maps; Methods; North Carolina; Outcome; Outcomes Research; Patients; Population Heterogeneity; Process; Protocols documentation; Research; Rural; Spottings; Techniques; Training; Translational Research; United States National Institutes of Health; Universities; Virginia; Work; Workforce Development; biomedical imaging; clinical center; community engaged research; community engagement; data interoperability; ethnic minority population; health difference; health disparity; health equity; health equity promotion; improved; innovation; machine learning method; medical schools; member; opioid overdose; participant enrollment; patient population; practice-based research network; programs; racial minority population; racial population; recruit; rural patients; telehealth; timeline; tool; vulnerable community

Building on the VCU C. Kenneth and Dianne Wright Center for Clinical and Translational Research and its research endowment, the Wright Regional Center for Clinical and Translational Science (Wright Regional CCTS) is a collaboration of partner institutions that serves regions of Virginia and North Carolina, including Eastern Virginia Medical School, a community focused medical school in Norfolk, Virginia with a strong community engaged research program in low income housing; Old Dominion University, a diverse public university in Norfolk Virginia with strengths in machine learning and AI techniques for biomedical data; Virginia Commonwealth University, a public university in Richmond, Virginia which has been a CTSA hub since 2010, with strengths in community engaged research; and Virginia State University, a Historically Black College and University with expertise to advance workforce diversity. The Overall Objective of the Wright Regional CCTS is to advance health equity through actively engaging diverse communities, training a diverse research workforce, and supporting the rapid implementation of innovative clinical and translational science (CTS) with our partners and collaborators and throughout the CTSA program. This will be carried out though the following Specific Aims: Aim 1: Enhance translational research workforce development with a focus on diversity to ultimately enhance recruitment of diverse patient populations into clinical research. Aim 2: Use health outcomes data to develop tools and methods to document differences in health outcomes within the community to support the goal of achieving health equity. Aim 3: Promote protocol review and oversight to enhance the quality of clinical research and reduce the timeline for regulatory approval. Aim 4: Work together across partner and collaborator institutions to use informatics data and tools to promote interoperability of data for high impact clinical research. Aim 5: Build on our existing community engagement and telehealth infrastructure to enhance recruitment of hard-to-reach low income and rural patient populations into clinical research. Impact: The Wright Regional CCTS will build on our strengths in community engaged research to support innovative translational science tools to address health equity in collaboration with our partners and community. We will enhance the diversity and rural impact of our translational research workforce, extend protocol review and oversight processes to improve the quality and efficiency of clinical research, develop innovative methods to engaged hard to reach low-income and rural patient populations in clinical research, and disseminate and implement successful CTS programs in our community and across the CTSA network.

以 VCU C. Kenneth 和 Dianne Wright 临床和转化研究中心及其 研究捐赠，赖特地区临床和转化科学中心（赖特地区 CCTS） 是服务于弗吉尼亚州和北卡罗来纳州地区（包括东部地区）的合作伙伴机构的合作项目 弗吉尼亚医学院是一所位于弗吉尼亚州诺福克的以社区为重点的医学院，拥有强大的社区 参与低收入住房研究计划；旧道明大学是一所多元化的公立大学 弗吉尼亚州诺福克在生物医学数据的机器学习和人工智能技术方面具有优势；弗吉尼亚州 联邦大学是弗吉尼亚州里士满的一所公立大学，自 2010 年以来一直是 CTSA 中心， 具有社区参与研究的优势；和弗吉尼亚州立大学，一所历史悠久的黑人学院 拥有促进劳动力多元化专业知识的大学。 赖特地区 CCTS 的总体目标是通过积极促进健康公平 吸引多元化的社区，培训多元化的研究人员，并支持快速发展 与我们的合作伙伴和合作者实施创新的临床和转化科学（CTS） 以及整个 CTSA 计划。 这将通过以下具体目标来实现： 目标 1：加强转化研究队伍的发展，重点关注多样性，最终实现 加强招募不同患者群体参与临床研究。 目标 2：使用健康结果数据开发工具和方法来记录健康差异 社区内的成果，以支持实现健康公平的目标。 目标 3：促进方案审查和监督，以提高临床研究的质量并减少 监管部门批准的时间表。 目标 4：跨合作伙伴和协作机构共同努力，利用信息学数据和工具 促进高影响力临床研究数据的互操作性。 目标 5：以我们现有的社区参与和远程医疗基础设施为基础，加强招募 将难以接触到的低收入和农村患者群体纳入临床研究。 影响：赖特地区 CCTS 将利用我们在社区参与研究方面的优势来支持 与我们的合作伙伴和社区合作解决健康公平问题的创新转化科学工具。 我们将增强转化研究队伍的多样性和农村影响力，扩大方案审查 和监督流程，以提高临床研究的质量和效率，开发创新方法 努力让低收入和农村患者群体参与临床研究，并传播和 在我们的社区和整个 CTSA 网络中实施成功的 CTS 计划。