Wright Regional Center for Clinical and Translational Science

赖特临床和转化科学区域中心

• 批准号: 10617079
• 负责人: FREDERICK Gerard MOELLER
• 金额: $ 402.34万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2030-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10617079
• 关键词: Address; Affect; Agreement; All of Us Research Program; Ambulatory Care; COVID-19; COVID-19 pandemic; Clinical Research; Clinical Sciences; Collaborations; Communities; Data; Endowment; Epidemic; Equity; Ethnic Population; Faculty; Fostering; Funding; Goals; Health; Health Personnel; Historically Black Colleges and Universities; Housing; Informatics; Infrastructure; Institution; Leadership; Low income; Machine Learning; Maps; Methods; North Carolina; Outcome; Outcomes Research; Patients; Population Heterogeneity; Process; Protocols documentation; Research; Rural; Spottings; Techniques; Training; Translational Research; United States National Institutes of Health; Universities; Virginia; Work; Workforce Development; biomedical imaging; clinical center; community engaged research; community engagement; data interoperability; ethnic minority population; health difference; health disparity; health equity; health equity promotion; improved; innovation; machine learning method; medical schools; member; opioid overdose; participant enrollment; patient population; practice-based research network; programs; racial minority population; racial population; recruit; rural patients; telehealth; timeline; tool; vulnerable community

Building on the VCU C. Kenneth and Dianne Wright Center for Clinical and Translational Research and its research endowment, the Wright Regional Center for Clinical and Translational Science (Wright Regional CCTS) is a collaboration of partner institutions that serves regions of Virginia and North Carolina, including Eastern Virginia Medical School, a community focused medical school in Norfolk, Virginia with a strong community engaged research program in low income housing; Old Dominion University, a diverse public university in Norfolk Virginia with strengths in machine learning and AI techniques for biomedical data; Virginia Commonwealth University, a public university in Richmond, Virginia which has been a CTSA hub since 2010, with strengths in community engaged research; and Virginia State University, a Historically Black College and University with expertise to advance workforce diversity. The Overall Objective of the Wright Regional CCTS is to advance health equity through actively engaging diverse communities, training a diverse research workforce, and supporting the rapid implementation of innovative clinical and translational science (CTS) with our partners and collaborators and throughout the CTSA program. This will be carried out though the following Specific Aims: Aim 1: Enhance translational research workforce development with a focus on diversity to ultimately enhance recruitment of diverse patient populations into clinical research. Aim 2: Use health outcomes data to develop tools and methods to document differences in health outcomes within the community to support the goal of achieving health equity. Aim 3: Promote protocol review and oversight to enhance the quality of clinical research and reduce the timeline for regulatory approval. Aim 4: Work together across partner and collaborator institutions to use informatics data and tools to promote interoperability of data for high impact clinical research. Aim 5: Build on our existing community engagement and telehealth infrastructure to enhance recruitment of hard-to-reach low income and rural patient populations into clinical research. Impact: The Wright Regional CCTS will build on our strengths in community engaged research to support innovative translational science tools to address health equity in collaboration with our partners and community. We will enhance the diversity and rural impact of our translational research workforce, extend protocol review and oversight processes to improve the quality and efficiency of clinical research, develop innovative methods to engaged hard to reach low-income and rural patient populations in clinical research, and disseminate and implement successful CTS programs in our community and across the CTSA network.

在VCU C上构建。Kenneth和Dianne Wright临床和转化研究中心及其 研究基金，赖特地区临床和转化科学中心（Wright Regional CCTS） 是一个合作伙伴机构，服务于弗吉尼亚州和北卡罗来纳州，包括东部地区的合作 弗吉尼亚医学院，一所以社区为重点的医学院，位于弗吉尼亚州诺福克，拥有强大的社区 从事低收入住房研究计划;老自治领大学，一个多元化的公立大学， 弗吉尼亚州诺福克，在生物医学数据的机器学习和人工智能技术方面具有优势;弗吉尼亚州 联邦大学是弗吉尼亚州里士满的一所公立大学，自2010年以来一直是CTSA的中心， 在社区参与研究方面具有优势;弗吉尼亚州立大学，一所历史悠久的黑人学院， 大学拥有促进劳动力多样性的专业知识。 赖特地区CCTS的总体目标是通过积极的措施来促进健康公平。 参与不同的社区，培训多样化的研究队伍，并支持快速发展 与我们的合作伙伴和合作者实施创新的临床和转化科学（CTS） 以及整个CTSA计划 这将通过以下具体目标来实现： 目标1：加强翻译研究队伍的发展，重点是多样性， 加强招募不同的患者群体参与临床研究。 目标2：利用健康结果数据开发记录健康差异的工具和方法 社区内的成果，以支持实现卫生公平的目标。 目标3：促进方案审查和监督，以提高临床研究的质量，减少 监管批准的时间轴。 目标4：在伙伴和合作机构之间开展合作，利用信息学数据和工具， 促进高影响力临床研究数据的互操作性。 目标5：在我们现有的社区参与和远程医疗基础设施的基础上，加强招聘 难以接触到的低收入和农村患者人群的临床研究。 影响：赖特地区CCTS将利用我们在社区参与研究方面的优势， 创新的转化科学工具，以解决与我们的合作伙伴和社区合作的健康公平。 我们将加强我们的转化研究队伍的多样性和农村影响，扩大方案审查， 和监督过程，以提高临床研究的质量和效率，开发创新方法， 在临床研究中努力接触低收入和农村患者群体，并传播和 在我们的社区和整个CTSA网络中实施成功的CTS计划。