Diversity Supplement: Personalized screening for lung cancer: the importance of co-existing chronic conditions to clinical practice and policy

多样性补充：肺癌的个性化筛查：共存慢性病对临床实践和政策的重要性

• 批准号: 10598740
• 负责人: Dejana K Braithwaite
• 金额: $ 5.54万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10598740
• 关键词: Adult; African American; Age; American Cancer Society; Assessment tool; Attention; Cancer Etiology; Cancer Intervention; Cancer Patient; Cessation of life; Chronic; Chronic Obstructive Pulmonary Disease; Complex; Data; Decision Making; Development; Diagnosis; Diagnostic Procedure; Disease; Disparity; Doctor of Philosophy; Early Diagnosis; Elderly; Electronic Health Record; Eligibility Determination; Epidemiologic Methods; Epidemiology; Ethnic Origin; Florida; Funding; Future; Geography; Goals; Grant; Health; Impairment; Infrastructure; Intervention; K-Series Research Career Programs; Knowledge; Life Expectancy; Link; Lung; Malignant neoplasm of lung; Manuscripts; Mentors; Modeling; Morbidity - disease rate; Non-Small-Cell Lung Carcinoma; Observational Study; Outcome; Participant; Patient-Focused Outcomes; Patients; Persons; Policies; Population; Procedures; Prospective cohort; Provider; Public Health; Pulmonary Emphysema; Race; Recommendation; Research; Research Personnel; Retrospective cohort; Risk; Risk Factors; Smoker; Smoking History; Socioeconomic Status; Spottings; Statistical Methods; Therapeutic procedure; Thoracic Radiography; Time; Training; Universities; Washington; Work; Writing; cancer health disparity; cancer surgery; clinical practice; cohort; comorbidity; compare effectiveness; data integration; data standards; doctoral student; early screening; experience; former smoker; functional status; health disparity; high risk; improved; low dose computed tomography; lung cancer screening; meetings; member; models and simulation; multiple chronic conditions; patient oriented; patient population; personalized screening; programs; pulmonary function; randomized, clinical trials; repository; routine screening; screening; screening guidelines; simulation; skills; surveillance imaging; therapy design

PROJECT SUMMARY/ABSTRACT This application seeks to support Caretia Washington, MD/PhD student, with a diversity supplement. Ms. Washington is an African-American, U.S. citizen who is currently in a PhD program in Public Health at the University of Florida, Gainesville. This supplement will support mentoring and supervised research experience that will help her to become an independent investigator. Ms. Washington’s mentor will be Dejana Braithwaite, PhD, MSc. In this diversity supplement, we propose to identify a retrospective cohort of stage I/II NSCLC patients (n=2,000) in OneFlorida to provide the first detailed assessment of imaging surveillance utilization and survival by levels of comorbidity and functional status as well as the first assessment of the impact of baseline levels and changes in comorbidity and functional status on patient outcomes. Completion of this project will inform future analysis of lung cancer disparities in the PLuS cohort. As the diversity supplement candidate, Ms. Washington, will gain essential experience in epidemiology and cancer disparities as well as statistical methods used to evaluate the multi-level causes of these disparities. Over a two-year period, Ms. Washington will engage in a training plan to focus on the following objectives: 1) training in epidemiology methods, 2) training in quantitative skills and statistical methods, and 3) professional development via grant and manuscript writing. The knowledge, skills, and experience that I will gain by completing this training and research plan will make me a competitive applicant for future career development awards such as F31, which is her next step in becoming an independent health disparities researcher.

项目总结/摘要 此应用程序旨在支持Caretia华盛顿，医学博士/博士生，与多样性补充。女士 华盛顿是一名非洲裔美国人，美国公民，目前正在纽约大学攻读公共卫生博士学位。 佛罗里达大学，盖恩斯维尔。这一补充将支持指导和监督的研究经验 帮助她成为一名独立调查员华盛顿女士的导师将是德贾娜·布雷斯韦特， 博士、理学硕士在本多样性补充中，我们建议确定一个I/II期NSCLC患者的回顾性队列 （n= 2，000）在OneFlorida，提供成像监测利用率和生存率的首次详细评估 以及对基线水平影响的首次评估， 合并症和功能状态的变化对患者结局的影响。该项目的完成将告知未来 PLuS队列中肺癌差异的分析。作为多样性补充候选人，华盛顿女士， 将获得流行病学和癌症差异以及统计方法的基本经验， 评估这些差异的多层次原因。在两年的时间里，华盛顿女士将参与一项 培训计划将侧重于以下目标：1）流行病学方法培训，2）定量 技能和统计方法，以及3）通过赠款和手稿写作的专业发展。知识， 技能和经验，我将通过完成这项培训和研究计划获得将使我成为一个有竞争力的 申请未来的职业发展奖项，如F31，这是她成为独立的下一步 健康差异研究员。