Diversity Supplement: Personalized screening for lung cancer: the importance of co-existing chronic conditions to clinical practice and policy

项目摘要/摘要 本申请旨在通过多样性补充来支持医学博士学生Caretia Washington。女士。 华盛顿是一名非裔美国人，美国公民，目前在哈佛大学公共卫生专业攻读博士学位 佛罗里达大学盖恩斯维尔分校。本补充资料将支持指导和监督研究体验 这将有助于她成为一名独立调查员。华盛顿的导师将是Dejana Braithwaite， 博士、硕士在这份多样性补充资料中，我们建议确定I/II期非小细胞肺癌患者的回顾性队列。 (n=2,000)，以提供第一次详细的成像监视利用和生存评估 按合并症水平和功能状态以及对基线水平和 合并症和功能状态的变化对患者预后的影响。该项目的完成将通知未来 肺癌在加队列中的差异分析。作为多元化补充候选人，华盛顿女士， 将获得流行病学和癌症差异方面的基本经验以及用于 评估造成这些差异的多层次原因。在两年的时间里，华盛顿女士将参与一项 培训计划侧重于以下目标：1)流行病学方法培训；2)量化培训 技能和统计方法，以及3)通过拨款和手稿写作实现职业发展。这些知识， 通过完成这项培训和研究计划，我将获得的技能和经验将使我成为一个有竞争力的人 申请F31等未来职业发展奖，这是她成为独立人士的下一步 健康差距研究人员。

PROJECT SUMMARY/ABSTRACT This application seeks to support Caretia Washington, MD/PhD student, with a diversity supplement. Ms. Washington is an African-American, U.S. citizen who is currently in a PhD program in Public Health at the University of Florida, Gainesville. This supplement will support mentoring and supervised research experience that will help her to become an independent investigator. Ms. Washington’s mentor will be Dejana Braithwaite, PhD, MSc. In this diversity supplement, we propose to identify a retrospective cohort of stage I/II NSCLC patients (n=2,000) in OneFlorida to provide the first detailed assessment of imaging surveillance utilization and survival by levels of comorbidity and functional status as well as the first assessment of the impact of baseline levels and changes in comorbidity and functional status on patient outcomes. Completion of this project will inform future analysis of lung cancer disparities in the PLuS cohort. As the diversity supplement candidate, Ms. Washington, will gain essential experience in epidemiology and cancer disparities as well as statistical methods used to evaluate the multi-level causes of these disparities. Over a two-year period, Ms. Washington will engage in a training plan to focus on the following objectives: 1) training in epidemiology methods, 2) training in quantitative skills and statistical methods, and 3) professional development via grant and manuscript writing. The knowledge, skills, and experience that I will gain by completing this training and research plan will make me a competitive applicant for future career development awards such as F31, which is her next step in becoming an independent health disparities researcher.