Administrative Core

行政核心

• 批准号: 10242674
• 负责人: Charles Wood
• 金额: $ 0.24万
• 依托单位: UNIVERSITY OF NEBRASKA LINCOLN
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-15 至 2021-10-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10242674
• 关键词: AIDS related cancer; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Africa; Area; Biomedical Research; Biometry; Cancer Hospital; Cancer Research Infrastructure; Chronic; Climate; Clinical Treatment; Collaborations; Communication; Communities; Complex; Country; Development; Diagnosis; Disease; Elements; Ensure; Environment; Epidemic; Epidemiology; Eye Neoplasms; Female; Goals; HIV-1; Health; Healthcare Systems; Hospitals; Human Resources; Immunosuppression; Individual; Infrastructure; Institution; Interdisciplinary Study; Kaposi Sarcoma; Laboratories; Lead; Leadership; Link; Logistics; Malignant Neoplasms; Medical center; Mentors; Mission; Molecular; Molecular Virology; Nebraska; Oncology; Outcomes Research; Pathogenesis; Pathology; Policies; Prevalence; Prevention; Process; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Project Summaries; Research Support; Research Training; Resource Sharing; Resources; Screening for cancer; Series; Teaching Hospitals; Technology Transfer; Training Activity; United States; United States National Institutes of Health; Universities; Viral; Work; Zambia; anticancer research; antiretroviral therapy; cancer diagnosis; cancer therapy; career; clinical care; design; male; meetings; member; neglect; next generation; ocular surface squamous neoplasia; potential biomarker; programs; research facility; success; virology

ABSTRACT/PROJECT SUMMARY The research theme of the proposed consortium focuses on the early detection of cancer, deciphering cancer pathogenesis, and the identification of potential biomarkers of Kaposi’s Sarcoma (KS) and ocular surface squamous neoplasia (OSSN), two of the most prevalent AIDS-associated cancers in Zambia. The Zambia AIDS Malignancies Diagnosis and Pathogenesis Program (ZAMDAPP)’s goal, which will link key expertise and resources of the Nebraska Center for Virology at the University of Nebraska-Lincoln, University of Zambia University Teaching Hospital, and Zambia’s Cancer Disease Hospital (CDH), is to develop the CDH cancer research infrastructure in three areas critical to the consortium’s overall research theme: cancer diagnosis, viral oncology, and cancer treatment. An Administrative Core will provide the administrative and programmatic leadership and infrastructure necessary to ensure the consortium functions efficiently and effectively. The Administrative Core will pursue four specific aims: 1) provide the administrative expertise and resources necessary to support the consortium’s Career Enhancement Core, Shared Resources Cores, and research projects in the accomplishment of their goals and specific aims; 2) implement a consortium-wide series of operational processes designed to create a collaborative research environment and build capacity for increased self-sufficiency in Zambian health institutions; 3) provide communications infrastructure to engage key stakeholders and promote the consortium locally and globally; and 4) establish and cultivate a strong working relationship with an External Advisory Group composed of key stakeholders and expertise leaders to connect research efforts with Zambian communities and identify research outcomes that will inform healthy policy changes. The organization of the Administrative Core is designed to be responsive, inclusive, and robust, which is essential to successfully address the broad mission and complex relationships within ZAMDAPP, among partnering and collaborating institutions, and with NIH. This core will focus on meeting the needs of the partnership and collaborators in the current climate of rapidly changing scientific and technological advances, which will result in a sustainable consortium with vibrant research programs that work toward the reduction of cancer in Africa.

摘要/项目总结 拟议联盟的研究主题重点是癌症的早期检测、破译癌症 发病机制，以及卡波西肉瘤（KS）和眼表的潜在生物标志物的鉴定 鳞状细胞瘤（OSSN）是赞比亚最流行的两种艾滋病相关癌症。赞比亚 艾滋病恶性肿瘤诊断和发病机制计划（ZAMDAPP）的目标，这将把关键的专业知识， 内布拉斯加大学林肯分校内布拉斯加病毒学中心的资源，赞比亚大学 大学教学医院和赞比亚的癌症医院（CDH）正在开发CDH癌症 研究基础设施在三个领域的关键联盟的整体研究主题：癌症诊断，病毒 肿瘤学和癌症治疗。一个行政核心将提供行政和方案 确保联合体高效和有效运作所需的领导和基础设施。的 行政核心将追求四个具体目标：1）提供行政专业知识和资源 支持联盟的职业提升核心，共享资源核心和研究所需的 （2）实施一系列联合体范围的 旨在创造合作研究环境和建设能力的业务流程， 提高赞比亚卫生机构的自给自足程度; 3）提供通信基础设施， 关键利益相关者，并在本地和全球范围内推广该联盟;以及4）建立和培养一个强大的 与由主要利益相关者和专业知识领导人组成的外部咨询小组建立工作关系， 将研究工作与赞比亚社区联系起来，并确定研究成果， 政策变化。行政核心的组织旨在响应，包容， 这对于成功地处理内部广泛的使命和复杂的关系至关重要 ZAMDAPP，在伙伴和合作机构之间，并与NIH。这一核心将侧重于满足 伙伴关系和合作者在当前科学和技术迅速变化的环境中的需求 技术进步，这将导致一个可持续的联盟与充满活力的研究计划， 减少非洲的癌症。