Comparative Virology Research Training Program

项目摘要/摘要 拟议的比较病毒学研究培训计划(T32计划)将利用 来自内布拉斯加-林肯大学(UNL)和内布拉斯加医学院的19名教职员工 该中心为博士生提供有关人类、动物和植物病毒的比较研究培训。 有了这种比较的定位，该项目处于培养生物医学研究人员的理想位置 有能力提供有关传染性病毒疾病的专业知识并应用新获得的知识和 基础和应用生物医学研究、动植物健康、生物防御准备和新兴领域的技能 疾病。T32计划的长期目标是培养一支初级科学家和研究人员队伍 具有良好的病毒发病机制基础知识和实验室研究经验。 该计划的具体目标是：1)为博士前实习生提供一个出色的培训环境 接受病毒感染和疾病方面的卓越教育，为他们在一系列领域取得成功做好准备 预期的职业，从学术界到政府再到私营部门；2)支持正在进行的培训工作 人类、动物和植物病毒和生物信息学，围绕比较研究经验在 不同的病毒宿主系统；以及3)促进学员和教职员工之间的沟通和合作 通过核心课程和方案活动，旨在利用亲密的培训和研究环境 由内布拉斯加州病毒学中心提供，以及教师导师的良好培训记录。学生 1)已被UNL生物科学学院的博士项目录取 本科学业成绩和GRE成绩以及2)表示对T32项目感兴趣的人 被定位为潜在的实习生。这些潜在的实习生将在他们毕业的1-2年内得到支持 在第二年年底申请T32课程之前，用机构资金进行课程。学生将被 根据导师的推荐被选为T32实习生，他们的学术/研究表现 头两年，以及他们在被T32计划录取之前成为成功研究人员的潜力 在第三年开始时，NIH基金支持学员的五年计划的第三到第四年，与导师实验室 资助覆盖五年级。除了在导师的专业课程和研究经验 在实验室，受训者将接受生物信息学方面的培训；研究伦理和勇气方面的指导； 关于学术界以外的职业道路的指导，包括获得行业和国际实习机会； 教学经验；参加年度研讨会。预期的结果是，这一计划将 为计划中的12名学员提供支持，他们将在研究设计、方法、 和分析，从而做好准备在学术界、政府、 以及使他们能够抗击当前和新出现的病毒传染病的产业。

PROJECT SUMMARY/ABSTRACT The proposed Comparative Virology Research Training Program (T32 Program) will leverage the expertise of 19 faculty members from the University of Nebraska-Lincoln (UNL) and the University of Nebraska Medical Center to provide comparative research training for pre-doctoral students in human, animal, and plant viruses. With this comparative orientation, the program is ideally positioned to develop biomedical researchers who are equipped to lend expertise regarding infectious viral diseases and to apply newly acquired knowledge and skills to basic and applied biomedical research, animal and plant health, biodefense readiness, and emerging diseases. The long-range goal of this T32 Program is to develop a cadre of junior scientists and researchers who are well grounded in a fundamental knowledge of viral pathogenesis and laboratory research experience. The specific aims of the program are to: 1) Provide a stellar training environment where pre-doctoral trainees receive an outstanding education in viral infections and disease that prepares them to succeed in a range of anticipated careers, from academia to government to the private sector; 2) Support ongoing training efforts in human, animal, and plant viruses and bioinformatics, coalescing around comparative research experiences in different viral-host systems; and 3) Foster communication and collaboration among trainees and faculty through core courses and program activities designed to exploit the intimate training and research environment provided at the Nebraska Center for Virology and the strong training record of faculty mentors. Students who have 1) been accepted into the UNL School of Biological Sciences PhD program based on excellent undergraduate academic records and GRE scores and 2) expressed interest in the T32 Program will be targeted as potential trainees. These potential trainees will be supported during Years 1-2 of their graduate program with institutional funds before applying to the T32 Program at the end of Year 2. Students will be selected as T32 trainees based on their mentor's recommendation, their academic/research performance in the first two years, and their potential to be successful researchers before being admitted into the T32 Program at the onset of Year 3. NIH funds support Years 3-4 of a trainee's five-year program, with mentor laboratory funding covering Year 5. In addition to specialized coursework and research experiences in mentor laboratories, trainees will receive training in bioinformatics; instruction in research ethics and grantsmanship; guidance regarding career paths beyond academia, including access to industry and international internships; teaching experience; and participate in an annual symposium. The expected outcome is that this program will support a projected 12 trainees who will graduate with a strong background in research design, methodology, and analysis and thus be well equipped to pursue a range of career opportunities in academia, government, and industry that enable them to confront current and emerging viral infectious diseases.