Comparative Virology Research Training Program

项目概要/摘要 拟议的比较病毒学研究培训计划（T32计划）将利用 来自内布拉斯加大学林肯分校（UNL）和内布拉斯加大学医学院的19名教师 该中心为人类、动物和植物病毒的博士预科生提供比较研究培训。 有了这个比较方向，该计划是理想的定位，以发展生物医学研究人员谁是 具备提供有关传染性病毒性疾病的专业知识和应用新获得的知识的能力， 基础和应用生物医学研究、动植物健康、生物防御准备和新兴技术的技能 疾病T32计划的长期目标是培养一批年轻科学家和研究人员 他们在病毒发病机理的基础知识和实验室研究经验方面有很好的基础。 该计划的具体目标是：1）提供一个一流的培训环境， 在病毒感染和疾病方面接受出色的教育，使他们能够在一系列领域取得成功， 预期的职业，从学术界到政府到私营部门; 2）支持正在进行的培训工作， 人类，动物和植物病毒和生物信息学，结合比较研究经验， 不同的病毒宿主系统; 3）促进学员和教师之间的沟通和合作 通过核心课程和计划活动，旨在利用亲密的培训和研究环境 提供的内布拉斯加州中心病毒学和教师导师的强大的培训记录。的学生 1）已被接受进入生物科学博士课程的UNL学校基于优秀的 本科学业成绩和GRE成绩，2）表示对T32课程感兴趣， 作为潜在的实习生。这些潜在的学员将在毕业后的第1-2年获得支持 在第二年年底申请T32计划之前，先用机构资金申请该计划。学生将 根据导师的推荐、他们在以下方面的学术/研究表现， 前两年，以及他们在被T32计划录取之前成为成功研究人员的潜力 在第三年开始的时候。NIH资金支持实习生五年计划的第3-4年，与导师实验室 资金覆盖5年。除了专业的课程和研究经验，在导师 实验室，受训人员将接受生物信息学培训;研究道德和伦理指导; 关于学术界以外职业道路的指导，包括进入行业和国际实习的机会; 教学经验;并参加年度研讨会。预期的结果是，该计划将 支持预计12名受训人员，他们将在研究设计，方法， 和分析，从而有能力在学术界，政府， 和工业，使他们能够应对当前和新出现的病毒性传染病。

PROJECT SUMMARY/ABSTRACT The proposed Comparative Virology Research Training Program (T32 Program) will leverage the expertise of 19 faculty members from the University of Nebraska-Lincoln (UNL) and the University of Nebraska Medical Center to provide comparative research training for pre-doctoral students in human, animal, and plant viruses. With this comparative orientation, the program is ideally positioned to develop biomedical researchers who are equipped to lend expertise regarding infectious viral diseases and to apply newly acquired knowledge and skills to basic and applied biomedical research, animal and plant health, biodefense readiness, and emerging diseases. The long-range goal of this T32 Program is to develop a cadre of junior scientists and researchers who are well grounded in a fundamental knowledge of viral pathogenesis and laboratory research experience. The specific aims of the program are to: 1) Provide a stellar training environment where pre-doctoral trainees receive an outstanding education in viral infections and disease that prepares them to succeed in a range of anticipated careers, from academia to government to the private sector; 2) Support ongoing training efforts in human, animal, and plant viruses and bioinformatics, coalescing around comparative research experiences in different viral-host systems; and 3) Foster communication and collaboration among trainees and faculty through core courses and program activities designed to exploit the intimate training and research environment provided at the Nebraska Center for Virology and the strong training record of faculty mentors. Students who have 1) been accepted into the UNL School of Biological Sciences PhD program based on excellent undergraduate academic records and GRE scores and 2) expressed interest in the T32 Program will be targeted as potential trainees. These potential trainees will be supported during Years 1-2 of their graduate program with institutional funds before applying to the T32 Program at the end of Year 2. Students will be selected as T32 trainees based on their mentor's recommendation, their academic/research performance in the first two years, and their potential to be successful researchers before being admitted into the T32 Program at the onset of Year 3. NIH funds support Years 3-4 of a trainee's five-year program, with mentor laboratory funding covering Year 5. In addition to specialized coursework and research experiences in mentor laboratories, trainees will receive training in bioinformatics; instruction in research ethics and grantsmanship; guidance regarding career paths beyond academia, including access to industry and international internships; teaching experience; and participate in an annual symposium. The expected outcome is that this program will support a projected 12 trainees who will graduate with a strong background in research design, methodology, and analysis and thus be well equipped to pursue a range of career opportunities in academia, government, and industry that enable them to confront current and emerging viral infectious diseases.