Graduate Training in Cellular and Molecular Pathogenesis of Human Diseases

项目摘要/摘要 细胞和分子病理学(CMP)研究生培训计划是加州大学的一个合资项目 威斯康星州(威斯康星州)-麦迪逊研究生院，病理与实验室医学系和 医学与公共卫生学院(SMPH)CMP提供严格的基础基础教学培训 生物医学与跨学科和创新训练相结合在重大疾病发病机制中的应用 人类疾病。《议定书》课程的目标是创造一个激励和健全的智力环境。 在动态的基础和临床翻译研究氛围中进行博士前培训，以便 培养将生物学知识转化为临床应用所需的技能。生物医学研究生 面向未来的培训要求一流的学术科学家毕业时具有适当的可操作性， 技术和专业技能，使他们能够在学术界、工业界从事不同的生物科学职业 或者是政府。《议定书》项目的主要任务是响应这一需求，并为我们的 毕业生将在快速发展的生物医学研究领域从事富有成效的职业生涯。该计划提供 可操作性(深入的知识，严谨和可重复的实验设计，批判性思维)，技术 (教授最先进的方法、严谨和可再现性)和专业(职业发展、境内流离失所者和 其他机会)确保学生成功的技能。课程的总体目标是教育学员，使他们 他们对病理学和分子医学有基本的了解，并有深入的研究 结合病理生物学和转化性临床研究的经验。《议定书》的具体目标是 通过实施受监控的国内流离失所者，确保最佳的博士毕业率和学位时间，学生 成功和进度监控。《议定书》《议定书》的目标将纳入该计划打算取得的可衡量成果 例如适当的完成率、职业介绍结果和学生保留率。这个 该项目吸引了来自24个系的85名博士、医学博士或医学博士资助的教员培训人员。我们要求 在分子医学项目下培训了8名博士前学生。受训人员将在 他们训练的第一年或第二年。候选人将根据对研究的承诺来选择 通过研究经验、推荐信和增强多样性和 为我国与健康相关的研究需求做出重大贡献。我们的课程提供 现代病理生物学基本概念的跨学科和综合培训，重点是 研究人类疾病的生化、细胞和分子方法，包括统计学方面的培训， 严谨、可重复性和负责任的研究行为。帮助学生开展教学和培训 通过委员会服务、演讲和研讨会教学，具备领导能力。拟议中的计划 提供基本知识基础、研究经验和对转化型临床的理解 研究是我们毕业生取得成功所必需的。

PROJECT SUMMARY/ABSTRACT The Cellular and Molecular Pathology (CMP) Graduate Training Program is a joint venture of the University of Wisconsin (UW)-Madison Graduate School, the Department of Pathology & Laboratory Medicine and the School of Medicine and Public Health (SMPH). CMP provides rigorous didactic training in fundamental basic biomedical sciences combined with interdisciplinary and innovative training in the pathogenesis of major human diseases. The goal of the CMP program is to create a stimulating and robust intellectual environment for predoctoral training embedded in a dynamic basic and clinical translational research atmosphere in order to develop the skills needed to move biological knowledge toward clinical application. Biomedical Graduate Training for the future demands that first rate academic scientists graduate with appropriate operational, technical and professional skills that will position them for diverse bioscience careers in academia, industry or government. The primary mission of the CMP program is to answer this demand and prepare our graduates for productive careers in the rapidly evolving biomedical research field. The program provides operational (in-depth knowledge, rigorous and reproducible experimental design, critical thinking), technical (teaching state-of-the-art methods, rigor and reproducibility) and professional (career development, IDPs and other opportunities) skills to ensure student success. The overall objective of CMP is to educate trainees so that they have a fundamental knowledge of pathology and molecular medicine, and have an in-depth research experience that combines pathobiological and translational clinical research. CMP’s specific objective is to ensure optimal PhD completion rates and time-to-degree with the implementation of monitored IDPs, student success and progress monitoring. CMP objectives will integrate measurable outcomes the program intends to achieve, such as appropriate completion rates, career placement outcomes and student retention rates. The Program draws 85 PhD, MD/PhD or MD funded faculty trainers from 24 departments. We are requesting training of eight pre-doctoral students under the Molecular Medicine Program. Trainees will be supported in the first or second year of their training. Candidates will be selected based on commitment to research documented by research experience, letters of recommendation and the potential to enhance diversity and make significant contributions toward the health-related research needs of our nation. Our curriculum provides interdisciplinary and integrated training in fundamental concepts in modern pathobiology with an emphasis on biochemical, cellular and molecular approaches to the study of human disease, including training in statistics, rigor and reproducibility and responsible conduct in research. CMP helps students to develop teaching and leadership skills through committee service, presentations and workshop teaching. The proposed program provides the fundamental knowledge base, research experience, and understanding of translational clinical research necessary for the success of our graduates.