An Integrated Software Platform for Accelerating Image-Driven Ophthalmic Research and Driving New Insights and Endpoints to the Clinic
一个集成软件平台,用于加速图像驱动的眼科研究并为临床带来新的见解和终点
基本信息
- 批准号:10631602
- 负责人:
- 金额:$ 21.29万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-01 至 2023-08-31
- 项目状态:已结题
- 来源:
- 关键词:AcademyAddressAdoptionAge related macular degenerationAmericanAutomobile DrivingBackBiological MarkersClinicClinical ResearchClinical TrialsCodeCollectionCommunitiesCommunity DevelopmentsComputer softwareConsensusDataData DiscoveryDevelopmentDevicesDiabetic RetinopathyDigital Imaging and Communications in MedicineEnsureEye diseasesGlaucomaHealthcareImageMetadataMethodsModelingNational Eye InstituteOphthalmologyPainPatientsReadingResearchSpecific qualifier valueSystemTranslatingTranslationsVisionVisualizationbiomarker discoverydata lakedata standardsdirect applicationefficacy testingfallsimage archival systemimage processingimaging modalityimaging platforminnovationinsightinteroperabilitynew technologynon-complianceocular imagingresearch and developmentsafety testingtool
项目摘要
Project Summary
Translational Imaging Innovations (TII) is creating an integrated platform for the collection, curation, analysis
and sharing of ocular images and data. Our Integrated Translational Imaging™ platform integrates an electronic
research workflow management system with an image repository, or data lake, and provides methods for
controlling the flow of images and data to a visualization and image processing toolkit. We now address a specific
pain point within the Ophthalmology and Vision community: DICOM conformance. In 2021, the FDA officially
recognized DICOM as a consensus standard for Ophthalmic Image Management Systems, and the National Eye
Institute and American Academy of Ophthalmology issued a call to the ophthalmic device community to accelerate
adoption of DICOM. DICOM for ophthalmology consists of 12 separate standards. Building a DICOM image file
requires a) transforming a proprietary (or non-DICOM) image file into a DICOM image object, and b) populating
DICOM tags with metadata. DICOM specifies required tags and optional tags (even number tags per the standard)
and allows for non-standard proprietary tags (odd-numbered). Non-compliant image formats and proprietary tags
are widespread in ophthalmology, particularly in OCT. We therefore propose to build a DICOM image generator
into the TII ocuVault API and incorporate DICOM rendering into the TII image curation application, ocuLink.
The addition of DICOM reading and translation capabilities into ocuLink and ocuVault solves significant problems
for the ophthalmic research and development community. We provide an engine for providing control of the
images back to the owner. We apply a transparent, harmonized model that ensures that DICOM standard tools
can use .DCM files, while maintaining proprietary information where necessary. We apply the DICOM model to
image modalities where a DICOM supplement does not exist, accelerating the harmonization of new technologies
in constant development in ophthalmology.
Our AIMS are as follows: 1) Implement DICOM rendering into ocuLink; 2) Develop methods to translate proprietary
image formats to DICOM; 3) Develop an ocuVault – to – DICOM metadata mapping software utility; 4) Develop an
any – to – DICOM export method; 5) Develop DICOM-conformant metadata fill utility for files that do not have
embedded metadata; and 6) submit ocuLink and ocuVault for FDA 510(k) clearance as an Ophthalmic Imaging
Management Systems (FDA Product Code NFJ).
-1-
项目摘要
Translational Imaging Innovations(TII)正在创建一个集成平台,
以及眼部图像和数据的共享。我们的Integrated Translational Imaging™平台集成了电子
研究工作流管理系统,并提供了用于
控制图像和数据流向可视化和图像处理工具包。我们现在讨论一个具体的
眼科和视觉界的痛点:DICOM符合性。2021年,FDA正式
将DICOM视为眼科图像管理系统的共识标准,
研究所和美国眼科学会向眼科器械界发出呼吁,
采用DICOM。眼科DICOM由12个独立的标准组成。构建DICOM图像文件
要求a)将专有(或非DICOM)图像文件转换为DICOM图像对象,以及B)填充
带有元数据的DICOM标签。DICOM规定了所需标签和可选标签(根据标准,偶数标签)
并且允许非标准的专有标签(奇数编号的)。不兼容的图像格式和专有标签
在眼科,特别是OCT中广泛存在。因此,我们建议建立一个DICOM图像生成器
整合到TII ocuVault API中,并将DICOM渲染整合到TII图像管理应用程序ocuLink中。
将DICOM阅读和翻译功能添加到ocuLink和ocuVault解决了重大问题
为眼科研究和开发社区。我们提供了一种引擎,用于控制
图像返回给所有者。我们采用透明、协调的模型,确保DICOM标准工具
可以使用.DCM文件,同时在必要时维护专有信息。我们将DICOM模型应用于
不存在DICOM补充的图像模式,加速新技术的协调
在眼科学中不断发展。
我们的目标如下:1)实现DICOM渲染到ocuLink; 2)开发方法来翻译专有的
图像格式到DICOM; 3)开发ocuVault到DICOM元数据映射软件实用程序; 4)开发
任何到DICOM的导出方法; 5)为不具有DICOM的文件开发符合DICOM的元数据填充实用程序
嵌入式元数据;以及6)将ocuLink和ocuVault作为眼科成像提交FDA 510(k)许可
管理体系(FDA产品代码NFJ)。
-1-
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Eric L. Buckland其他文献
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{{ truncateString('Eric L. Buckland', 18)}}的其他基金
An Integrated Software Platform for Accelerating Image-Driven Ophthalmic Research and Driving New Insights and Endpoints to the Clinic
一个集成软件平台,用于加速图像驱动的眼科研究并为临床带来新的见解和终点
- 批准号:
10226822 - 财政年份:2020
- 资助金额:
$ 21.29万 - 项目类别:
Validating Automated Photoreceptor Analytics Software For Degenerative Eye Disease Research and Biopharma Clinical Trials.
验证用于退行性眼病研究和生物制药临床试验的自动光感受器分析软件。
- 批准号:
9918805 - 财政年份:2020
- 资助金额:
$ 21.29万 - 项目类别:
An Integrated Software Platform for Accelerating Image-Driven Ophthalmic Research and Driving New Insights and Endpoints to the Clinic
一个集成软件平台,用于加速图像驱动的眼科研究并为临床带来新的见解和终点
- 批准号:
9908389 - 财政年份:2020
- 资助金额:
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Choroidal Blood Flow Imaging with Spectral Domain OCT
使用谱域 OCT 进行脉络膜血流成像
- 批准号:
8780425 - 财政年份:2014
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Aspheric SDOCT Imaging System for Dry Eye and Cornea Diagnostics
用于干眼和角膜诊断的非球面 SDOCT 成像系统
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Pediatric Spectral Domain Optical Coherence Tomography
儿科谱域光学相干断层扫描
- 批准号:
8838894 - 财政年份:2009
- 资助金额:
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Pediatric Spectral Domain Optical Coherence Tomography
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8429508 - 财政年份:2009
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7219581 - 财政年份:2007
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