Perceptions on the use of medication for weight management fromteens, parents and pediatricians in the southwest.

西南地区青少年、家长和儿科医生对使用药物控制体重的看法。

• 批准号: 10626664
• 负责人: Alberta Sum-Yu Kong
• 金额: $ 0.61万
• 依托单位: UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-23 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10626664
• 关键词: Adolescent; Adolescent obesity; Adoption; Body Weight decreased; Caregivers; Center for Translational Science Activities; Child; Childhood; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Network; Collaborations; Competence; Consent; Consultations; Development Plans; Discipline; Educational Curriculum; Exposure to; Fenfluramine; Group Meetings; Heart Diseases; Heart Valves; Hispanic; Individual; Institutional Review Boards; Interview; Life Style Modification; Lifestyle Therapy; Literature; Medical; Medical Students; Mentors; New Mexico; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Overweight; Parents; Participant; Patient Recruitments; Perception; Pharmaceutical Preparations; Phase; Phentermine; Placebos; Population; Preparation; Publications; Qualitative Research; Quality of life; Recording of previous events; Regulation; Research; Research Methodology; Research Personnel; Research Project Grants; Risk; Self Assessment; Services; Structure; Teaching Method; Teenagers; Training; Underrepresented Minority; Universities; Weight Perception; Weight maintenance regimen; Weight-Loss Drugs; adult obesity; community engagement; experience; hands on research; interest; medical schools; parent project; pediatrician; recruit; side effect; skills; symposium

ABSTRACT The Medical Student Scholar (MSS) recently completed his 3rd year in medical school at the University of New Mexico School of Medicine. He is interested in research to build upon his medical training. Having experienced being obese as a child, he has a special interest in adolescent obesity. His background is that of a Hispanic underrepresented minority in the biomedical field and his diversity will be of great benefit on the proposed study entitled “Perceptions on the use of medication for weight management from teens, parents, and pediatricians in the southwest.” This formative study will contribute to the larger IDeA States Pediatric Clinical Trials Network’s planned clinical trial on phentermine + lifestyle therapy vs placebo + lifestyle therapy. Understanding adolescents’, caregivers’, and pediatricians’ perceptions of weight loss medications, especially phentermine, is critically important as there has been negative publicity on the weight loss drug, Fen-phen, in the 1990s. While the phentermine component was not the culprit that caused heart valve damage, the association of phentermine with Fen-phen may likely still be a concern for use among parents and pediatricians who are old enough to remember when the FDA ordered Fenfluramine to be removed from the market. The results of the MSS’s proposed study will be used to inform recruitment, retention, and implementation of the planned phentermine clinical trial. Through hands-on research experience, the PI will mentor the MSS to develop skills in basic qualitative research and increase his understanding of formative research that can be used in preparation of clinical trials in the pediatric population. The MSS will be supported by a team of experienced researchers with qualitative expertise and be exposed to the services at the UNM Clinical and Translational Science Center and the Community Engagement Research Core. He will be actively involved through training and take part in the study to meet competency in clinical research regulations, IRB submission, developing semi-structured interview guides, participant recruitment and consent, participant interviewing, and thematic analysis. Specific objectives are as follows: 1) Mentor will guide MSS in the proposed independent research project that augments and is integral to the parent project, and 2) MSS will leverage parent project experts and interprofessional collaboration for project actualization. Specific aims for the MSS: 1) Build MSS research skills over the course of the proposed formative study through an Individual Development Plan and self-assessment to provide structured oversight and employ a variety of teaching methods tailored to the MSS’s skills and needs including one-on-one sessions, current discipline specific literature curriculum, collaboration with study related team group meetings, consultation with team experts, opportunity to attend interdisciplinary local seminars and attendance at a national conference covering a topic relevant to the proposed project; 2) MSS will take active part in all phases of the formative study using basic qualitative research methodology, 3) MSS will present and submit findings for publication.

摘要 这位医学生学者(MSS)最近完成了他在纽约大学医学院的第三年学业 墨西哥医学院。他对研究感兴趣，以便在他的医学培训基础上再接再厉。经历过 作为一个肥胖的孩子，他对青少年肥胖症特别感兴趣。他的背景是一个 拉美裔在生物医学领域的代表性不足的少数族裔，他的多样性将对 一项名为《青少年、父母、青少年对使用药物控制体重的认知》的拟议研究 以及西南部的儿科医生。这项形成性的研究将有助于更大的想法国家儿科 临床试验网络计划进行的芬太尼+生活方式疗法与安慰剂+生活方式疗法的临床试验。 了解青少年、照顾者和儿科医生对减肥药物的看法，尤其是 芬太尼至关重要，因为在美国，减肥药芬芬一直受到负面宣传 20世纪90年代。虽然苯丙氨酸成分不是导致心脏瓣膜损伤的罪魁祸首，但 苯丙氨酸与芬酚的相关性可能仍然是父母和 年龄足够大的儿科医生记得FDA何时下令将芬氟拉明从 市场。MSS建议的研究结果将被用来为招聘、保留和 实施计划中的芬太尼临床试验。通过亲身实践的研究经验，PI将 指导MSS发展基础定性研究的技能并增加其对形成性研究的理解 可用于在儿科人群中准备临床试验的研究。将支持MSS 由一组经验丰富的具有质量专业知识的研究人员组成的团队，并接触到UNM的服务 临床和转化科学中心和社区参与研究核心。他将会积极地 通过培训参与研究，以满足临床研究法规的要求 提交、制定半结构化面试指南、参与者招募和同意、参与者 访谈和主题分析。 具体目标如下：1)导师将在拟议的独立研究项目中指导MSS 增强父项目，并且是父项目的组成部分；2)MSS将利用父项目专家和 跨专业协作以实现项目。 MSS的具体目标：1)在拟议的形成性学习过程中培养MSS的研究技能 通过个人发展计划和自我评估提供结构化监督并聘用 根据MSS的技能和需求量身定做的各种教学方法，包括一对一课程，目前 特定学科的文学课程，与学习相关的团队会议合作，咨询 团队专家，有机会参加跨学科的当地研讨会和参加全国会议 涵盖与拟议项目相关的主题；2)MSS将积极参与形成项目的所有阶段 使用基本的定性研究方法进行研究，3)MSS将提出并提交研究结果以供发表。