Core C: Bioinformatics and Genomics Core
核心 C:生物信息学和基因组学核心
基本信息
- 批准号:10627091
- 负责人:
- 金额:$ 32.34万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-04-15 至 2028-05-31
- 项目状态:未结题
- 来源:
- 关键词:ATAC-seqAgingArchivesAreaBioinformaticsCellsCharacteristicsChromatinCollaborationsCommunitiesCore FacilityCryoelectron MicroscopyCustomDataData AnalysesData SetDatabasesDistantEducational workshopEnvironmentEpigenetic ProcessFamily suidaeGene ExpressionGene Expression ProfileGenerationsGenesGenomicsGeographic LocationsGoalsHumanHuman ResourcesImageIndividualLinkLocationMapsMass Spectrum AnalysisMedical centerMetadataMethodsModelingMultiomic DataMusNatureNebraskaPathway AnalysisPathway interactionsPituitary GlandPolysaccharidesProteomicsProtocols documentationRattusResearchResearch Project GrantsResourcesSamplingScienceSignal TransductionSiteStructureTechniquesTechnologyTestingTissuesTrainingTraining ActivityTraining and InfrastructureUniversitiesValidationVariantVisualizationbioinformatics toolbiological researchcloud basedcomputer infrastructuredata accessdata analysis pipelinedifferential expressionexperimental analysisexperimental studygene productglycosylationinnovationmiRNA expression profilingmultiple omicsnext generation sequencingprogramsprotein expressionsearchable databasesingle-cell RNA sequencingsuccesstooltraining projecttranscriptome sequencingtranscriptomicsweb interfaceweb portalweb serviceswebinar
项目摘要
Project Summary/Abstract – Core C
Bioinformatics has become an integral part of biological research due to the high-throughput nature
of multi-omics experiments warranting the need for having the infrastructure and trained personnel
to support the advancement of science of the research projects. The Bioinformatics and Genomics
Core (Core C) will continue to serve as a linchpin in the overall success of the program project by
supporting the generation, storage, processing, analysis and accessing of experimental data. Core
C will be led by Drs. Babu Guda and James Eudy, who will provide complementary expertise in
Bioinformatics and Genomics areas, respectively. This Core is innovative by having a fully integrated
Bioinformatics as well as Genomics units within, which allows full spectrum access to cutting-edge
experimental and analytical techniques under one Core. The specific aims are: Aim 1: Support the
sequencing and analysis of multi-omics data for research projects. Aim 2: Integrative analysis and
functional characterization of significant genes, gene products, enriched pathways, and upstream
regulators for hypothesis generation and testing. Aim 3: Develop a web portal to centralize access to
multi-omics data from all research projects and to facilitate bioinformatics training activities. Core C will
make a big impact on the overall success of the project by providing resources, personnel support and
developing cutting-edge technologies and custom data analysis methods for all research projects.
Proposed cloud-based web portal backed by a searchable database provides easy access to all
experimental data, metadata, and the training materials facilitating synergistic interactions among the
project personnel across multiple sites.
项目概要/摘要-核心C
生物信息学由于其高通量的特性,已经成为生物学研究中不可或缺的一部分
多组学实验需要基础设施和训练有素的人员,
支持研究项目的科学进步。生物信息学与基因组学
核心(核心C)将继续作为该计划项目整体成功的关键,
支持实验数据的生成、存储、处理、分析和访问。核心
C将由Babu Guda博士和James Eudy博士领导,他们将在以下方面提供补充专业知识:
生物信息学和基因组学领域,分别。该核心是创新的,它具有完全集成的
生物信息学以及基因组学单位内,这使得全频谱访问尖端
实验和分析技术在一个核心下。具体目标是:目标1:支持
为研究项目测序和分析多组学数据。目标2:综合分析和
重要基因、基因产物、富集途径和上游的功能表征
用于假设生成和检验的调节器。目标3:开发一个门户网站,
这将有助于收集所有研究项目的多组学数据,并促进生物信息学培训活动。核心C将
通过提供资源、人员支持和
为所有研究项目开发尖端技术和定制数据分析方法。
拟议的基于云的门户网站由一个可搜索的数据库支持,
实验数据、元数据和培训材料促进了
多个地点的项目人员。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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CHITTIBABU GUDA其他文献
CHITTIBABU GUDA的其他文献
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{{ truncateString('CHITTIBABU GUDA', 18)}}的其他基金
Biomedical Informatics, Bioinformatics, and Cyberinfrastructure Enhancement Core
生物医学信息学、生物信息学和网络基础设施增强核心
- 批准号:
10478974 - 财政年份:2016
- 资助金额:
$ 32.34万 - 项目类别:
Biomedical Informatics, Bioinformatics, and Cyberinfrastructure Enhancement Core
生物医学信息学、生物信息学和网络基础设施增强核心
- 批准号:
10281662 - 财政年份:2016
- 资助金额:
$ 32.34万 - 项目类别:
Cataloging the subcellular and suborganellar proteomes of sequenced genomes
对测序基因组的亚细胞和亚细胞器蛋白质组进行编目
- 批准号:
8331447 - 财政年份:2009
- 资助金额:
$ 32.34万 - 项目类别:
Cataloging the subcellular and suborganellar proteomes of sequenced genomes
对测序基因组的亚细胞和亚细胞器蛋白质组进行编目
- 批准号:
8234952 - 财政年份:2009
- 资助金额:
$ 32.34万 - 项目类别:
Cataloging the subcellular and suborganellar proteomes of sequenced genomes
对测序基因组的亚细胞和亚细胞器蛋白质组进行编目
- 批准号:
8538440 - 财政年份:2009
- 资助金额:
$ 32.34万 - 项目类别:
Cataloging the subcellular and suborganellar proteomes of sequenced genomes
对测序基因组的亚细胞和亚细胞器蛋白质组进行编目
- 批准号:
7918788 - 财政年份:2009
- 资助金额:
$ 32.34万 - 项目类别:
Core C - Bioinformatics and Genomics Core
核心 C - 生物信息学和基因组学核心
- 批准号:
9280513 - 财政年份:2009
- 资助金额:
$ 32.34万 - 项目类别:
Cataloging the subcellular and suborganellar proteomes of sequenced genomes
对测序基因组的亚细胞和亚细胞器蛋白质组进行编目
- 批准号:
8138592 - 财政年份:2009
- 资助金额:
$ 32.34万 - 项目类别:
An integrated approach to infer and validate domain-domain interactions in protei
推断和验证 protei 中域-域交互的集成方法
- 批准号:
7367241 - 财政年份:2008
- 资助金额:
$ 32.34万 - 项目类别:
Nebraska Research Network in Functional Genomics
内布拉斯加州功能基因组学研究网络
- 批准号:
10624375 - 财政年份:2001
- 资助金额:
$ 32.34万 - 项目类别:
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