UNMC Bioinformatics Core

项目摘要 生物信息学核心在INBRE项目的总体成功中起到了林奇钉的作用，它促进了访问 向INBRE网络成员提供资源、专门知识、支持和培训，以使用计算 生物信息学中的资源和数据分析工具。简而言之，生物信息学是一门真正的跨学科 试图使用数学、统计学或计算机中的概念来解决生物问题的领域 科学，是在计算机的帮助下实现的。生物信息学已经成为 由于生物实验的高通量性质而进行的生物研究(广泛地称为“组学”) 数据)。因此，为收集开发计算基础设施的巨大需求随之而来， 处理、存储、分析和便利研究界使用这类数据。具有并行功能 计算机科学和高通量生物技术的发展，生物数据正在被 以一种比分析和理解更快的速度生成。此外，日新月异的 技术和数据分析工具使得跟上不断变化的环境变得更具挑战性 菲尔德。鉴于这种复杂性的性质，很难指望单个机构开发和维护 生物信息学方面的复杂基础设施和技术专长。INBRE项目的主要目标是 是向INBRE的所有成员提供这样的环境、技术、工具和支持 网络。生物信息学核心的主要目标包括开发所需的基础设施， 为生物信息学分析提供工具和支持，并培训INBRE学者和研究人员使用 设施和技术。

Project Summary The Bioinformatics Core acts as a lynch pin in the overall success of the INBRE project by facilitating access to resources, knowhow, support and training to the INBRE network members in the use of computational resources and data analysis tools in bioinformatics. In simple terms, bioinformatics is a truly interdisciplinary field that attempts to solve biological questions using concepts from mathematics, statistics or computer science, which are implemented with the aid of computers. Bioinformatics has become an integral part of biological research due to the high-throughput nature of biological experiments (broadly dubbed as `omics' data). Thus, a tremendous need ensued for developing computational infrastructure for the collection, processing, storage, analysis and facilitating the use of such data by the research community. With parallel developments in computer science and high-throughput technologies in biology, biological data is being generated at a way faster pace than it can be analyzed and make sense out of. Moreover, the ever-changing technologies and data analysis tools make it more challenging to upkeep with the changing landscape of this field. Given the nature of this complexity, it is hard to expect from individual institutions to develop and maintain sophisticated infrastructure and technical expertise in bioinformatics. The primary goal of the INBRE program is to provide such environment, technology, tools and support accessible to all members of the INBRE network. The main objectives of the Bioinformatics Core include the development of needed infrastructure, provide tools and support for bioinformatic analyses, and train the INBRE scholars and investigators in the use of facilities and technologies.