Training in Cardiovascular Research
心血管研究培训
基本信息
- 批准号:10626716
- 负责人:
- 金额:$ 46.16万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1994
- 资助国家:美国
- 起止时间:1994-07-01 至 2027-06-30
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
PROJECT ABSTRACT
Cardiovascular disease is the leading cause of death in the United States. There is an ongoing need to
provide multidisciplinary training for physician and PhD investigators who will devote a significant
component of their professional activity to understanding the pathophysiology and treatment of
cardiovascular disease. This is the 7th renewal application for the University of Utah (UofU) Cardiovascular
Research Training Program. Since its inception in 1984, this program has trained 113 individuals who have
largely gone on to pursue research careers. During the last training period (2016-2020), this training grant
supported 21 post-doctoral research trainees (5 MD/DOs, 16 PhDs) who all remain active at academic
institutions. Our trainees have authored 218 publications, with an average of 2 first-author publications
each. They have also received several grants and career development awards (e.g. NIH, American Heart
Association, NSF, ACS). This program continues to build on our unique strengths in cardiovascular
research at the UofU, spanning basic and mechanistic investigation across a range of model systems and
translational studies in humans. This training program unifies the three major cardiovascular research
centers at the UofU Health Sciences Center: The Nora Eccles Harrison Cardiovascular Research and
Training Institute (CVRTI), the Division of Cardiovascular Medicine at the School of Medicine, and the
Molecular Medicine Program (U2M2) at the Eccles Institute of Human Genetics. This training program
spans 13 UofU departments and includes 54 well-funded faculty mentors who lead exciting and productive
cardiovascular research programs. Each trainee will participate in a two-year training program that includes
a research project with a multidisciplinary mentoring committee, didactic coursework, and professional
development opportunities. With this renewal application, we continue to request support to prepare 8
postdoctoral trainees to be leaders in cardiovascular research. The next stage of the training program will
utilize an expanded mentor pool and implement a dual-leadership structure by two cardiology physician-
scientists (MPIs: Stavros Drakos, MD, PhD, and Robin Shaw, MD, PhD) whose interests span from basic
biochemistry to clinical trials. This renewal occurs at a time with the UofU is increasing its already sizeable
investment into cardiovascular research training. A $6M addition to the CVRTI is being constructed to
increase the number of cardiovascular research laboratories in an institute already fully dedicated to
cardiovascular research and training. Also there is a campus-wide Cardiovascular Strategic Plan being
implemented to enhance cardiovascular research and care and the UofU. The next five years of the training
program will leverage these new resources and opportunities at the UofU and represents a new era of
interdisciplinary collaborative cardiovascular research at our institution.
项目摘要
心血管疾病是美国人死亡的主要原因。持续需要
为医生和博士研究人员提供多学科培训,他们将投入大量的精力,
他们的专业活动的组成部分,以了解病理生理学和治疗
心血管疾病这是犹他州大学(UofU)心血管的第7次更新申请
研究培训计划。自1984年成立以来,该方案已培训了113人,
大部分人都在从事研究事业。在上一个培训期间(2016-2020年),
支持了21名博士后研究生(5名MD/DO,16名博士),他们都仍然活跃在学术界
机构职能体系我们的学员撰写了218篇出版物,平均2篇第一作者出版物
每个.他们还获得了几项赠款和职业发展奖(如NIH、美国心脏
协会、NSF、ACS)。该计划将继续建立在我们在心血管领域的独特优势之上
在UofU的研究,跨越一系列模型系统的基础和机械研究,
人类的翻译研究。该培训计划统一了三大心血管研究
UofU健康科学中心的中心:诺拉埃克尔斯哈里森心血管研究和
培训研究所(CVRTI)、医学院心血管医学部和
埃克尔斯人类遗传学研究所的分子医学项目(U2 M2)。这个培训项目
跨越13个UofU部门,包括54个资金充足的教师导师谁领导令人兴奋和富有成效的
心血管研究项目。每个受训者将参加为期两年的培训计划,其中包括
一个研究项目与多学科指导委员会,教学课程,和专业
发展机遇。在此更新申请中,我们继续请求支持以准备8
博士后培训人员将成为心血管研究的领导者。培训计划的下一阶段将
利用扩大的导师库,并实施由两名心脏病医生组成的双重领导结构-
科学家(MPI:Stavros Drakos,MD,PhD和Robin Shaw,MD,PhD),他们的兴趣范围从基本的
生物化学到临床试验。这种更新发生在UofU正在增加其已经相当大的时间
投资于心血管研究培训。CVRTI的600万美元扩建工程正在建设中,
增加心血管研究实验室的数量,研究所已经完全致力于
心血管研究和训练。此外,还有一个校园范围内的心血管战略计划,
该计划旨在加强心血管研究和护理以及UofU。未来五年的训练
该计划将利用UofU的这些新资源和机会,代表一个新的时代,
跨学科合作心血管研究。
项目成果
期刊论文数量(185)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Meningeal cells and glia establish a permissive environment for axon regeneration after spinal cord injury in newts.
- DOI:10.1186/1749-8104-6-1
- 发表时间:2011-01-04
- 期刊:
- 影响因子:3.6
- 作者:Zukor KA;Kent DT;Odelberg SJ
- 通讯作者:Odelberg SJ
A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis.
- DOI:10.1021/jacs.6b05719
- 发表时间:2016-09-14
- 期刊:
- 影响因子:15
- 作者:Jacobsen MT;Petersen ME;Ye X;Galibert M;Lorimer GH;Aucagne V;Kay MS
- 通讯作者:Kay MS
PDE3 inhibition in dilated cardiomyopathy.
PDE3抑制性心肌病。
- DOI:10.1016/j.coph.2011.09.001
- 发表时间:2011-12
- 期刊:
- 影响因子:4
- 作者:Movsesian, Matthew;Wever-Pinzon, Omar;Vandeput, Fabrice
- 通讯作者:Vandeput, Fabrice
Editorial Comment on: Inhibition of Suicidal Erythrocyte Death by Chronic Hypoxia by Tang et al. (From: Tang F, Feng L, Li R, Wang W, Liu H, Yang Q, Ge R-L. High Alt Med Biol 2019;20:112-119; DOI: 10.1089/ham.2017.0159).
编辑评论:唐等人通过慢性缺氧抑制自杀性红细胞死亡。
- DOI:10.1089/ham.2019.29017.stp
- 发表时间:2019
- 期刊:
- 影响因子:2.1
- 作者:Song,Jihyun;Tashi,Tsewang;Prchal,JosefT
- 通讯作者:Prchal,JosefT
Right Ventricular Involution: Big Changes in Small Hearts.
右心室复旧:小心脏的大变化。
- DOI:10.1016/j.jss.2019.05.048
- 发表时间:2019
- 期刊:
- 影响因子:0
- 作者:Bowen,MeganE;Selzman,CraigH;McKellar,StephenH
- 通讯作者:McKellar,StephenH
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Stavros George Drakos其他文献
COST EFFECTIVENESS ANALYSIS OF ECMO WITH ADJUNCT VENTRICULAR UNLOADING DEVICE COMPARED TO ECMO
- DOI:
10.1016/s0735-1097(24)04530-3 - 发表时间:
2024-04-02 - 期刊:
- 影响因子:
- 作者:
Kaan Raif;Stavros George Drakos;Craig H. Selzman;Joshua Horns;Joseph Tonna - 通讯作者:
Joseph Tonna
SPHINGOLIPIDS AS POTENTIAL SURROGATES OF MYOCARDIAL RECOVERY IN LEFT VENTRICULAR ASSIST DEVICE PATIENTS
- DOI:
10.1016/s0735-1097(23)00741-6 - 发表时间:
2023-03-07 - 期刊:
- 影响因子:
- 作者:
Rana Hamouche;Sean Tatum;Elizabeth Dranow;Christos P. Kyriakopoulos;Thirupura Sundari Shankar;Joseph Visker;Jing Ling;Konstantinos Sideris;Craig H. Selzman;Abdallah G. Kfoury;Josef Stehlik;Rami Alharethi;James C. Fang;Sutip Navankasattusas;William Holland;Scott Summers;Stavros George Drakos;Eleni Tseliou - 通讯作者:
Eleni Tseliou
IMPAIRED LIVER FUNCTION IS ASSOCIATED WITH HYPOTENSION AND ELEVATED RIGHT ATRIAL PRESSURE BUT NOT DEPRESSED CARDIAC INDEX IN CHRONIC HEART FAILURE
- DOI:
10.1016/s0735-1097(23)00919-1 - 发表时间:
2023-03-07 - 期刊:
- 影响因子:
- 作者:
Christos Kapelios;Eleni Tseliou;Rami Alharethi;Kevin Shah;Thomas Hanff;Christos P. Kyriakopoulos;Konstantinos Sideris;Iosif Taleb;Josef Stehlik;Spencer Carter;Abdallah G. Kfoury;William Caine;Craig H. Selzman;James C. Fang;Omar Wever-Pinzon;Stavros George Drakos - 通讯作者:
Stavros George Drakos
Functional and Structural Myocardial Improvement after LVAD Therapy: The U-NOVA Reverse Remodeling Stages
- DOI:
10.1016/j.cardfail.2019.07.190 - 发表时间:
2019-08-01 - 期刊:
- 影响因子:
- 作者:
Shah Palak;Mitchell Psotka;Iosif Taleb;Rami Alharethi;Mortada A. Shams;Omar Wever-Pinzon;Michael Yin;Federica Latta;Josef Stehlik;James C. Fang;Ramesh Singh;Craig H. Selzman;Abdallah Kfoury;Stavros George Drakos - 通讯作者:
Stavros George Drakos
HEALTH RELATED QUALITY OF LIFE AS PREDICTOR OF OUTCOMES IN HEART FAILURE WITH PRESERVED EJECTION FRACTION
- DOI:
10.1016/s0735-1097(23)01057-4 - 发表时间:
2023-03-07 - 期刊:
- 影响因子:
- 作者:
Konstantinos Sideris;Mingyuan Zhang;Alfonso F. Siu;Peter Wohlfahrt;Jincheng Shen;Christos P. Kyriakopoulos;Iosif Taleb;Omar Wever-Pinzon;Kevin Shah;Craig H. Selzman;Carlos Rodriguez Correa;Christos Kapelios;Lina M. Brinker;Rami Alharethi;Rachel Hess;Stavros George Drakos;Benjamin Adam Steinberg;Abdallah G. Kfoury;John A. Spertus;James C. Fang - 通讯作者:
James C. Fang
Stavros George Drakos的其他文献
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{{ truncateString('Stavros George Drakos', 18)}}的其他基金
Mechanism of Eccentric Cardiomyocyte Hypertrophy Secondary to Mitral Regurgitation
二尖瓣反流继发偏心心肌细胞肥大的机制
- 批准号:
10565204 - 财政年份:2023
- 资助金额:
$ 46.16万 - 项目类别:
Perm1 is a Novel Regulator of Cardiac Energetics and Function
Perm1 是一种新型的心脏能量和功能调节剂
- 批准号:
10547828 - 财政年份:2020
- 资助金额:
$ 46.16万 - 项目类别:
Perm1 is a Novel Regulator of Cardiac Energetics and Function
Perm1 是一种新型的心脏能量和功能调节剂
- 批准号:
10631449 - 财政年份:2020
- 资助金额:
$ 46.16万 - 项目类别:
Perm1 is a Novel Regulator of Cardiac Energetics and Function
Perm1 是一种新型的心脏能量和功能调节剂
- 批准号:
10730363 - 财政年份:2020
- 资助金额:
$ 46.16万 - 项目类别:
Perm1 is a Novel Regulator of Cardiac Energetics and Function
Perm1 是一种新型的心脏能量和功能调节剂
- 批准号:
10523981 - 财政年份:2020
- 资助金额:
$ 46.16万 - 项目类别:
Perm1 is a Novel Regulator of Cardiac Energetics and Function
Perm1 是一种新型的心脏能量和功能调节剂
- 批准号:
10156104 - 财政年份:2020
- 资助金额:
$ 46.16万 - 项目类别:
Understanding Myocardial Recovery in Diabetes and Heart Failure
了解糖尿病和心力衰竭的心肌恢复
- 批准号:
10426081 - 财政年份:2020
- 资助金额:
$ 46.16万 - 项目类别:
Understanding Myocardial Recovery in Diabetes and Heart Failure
了解糖尿病和心力衰竭的心肌恢复
- 批准号:
10595643 - 财政年份:2020
- 资助金额:
$ 46.16万 - 项目类别:
Clinical and Metabolic Signature of Recovered Myocardium in Human Heart Failure
人类心力衰竭恢复心肌的临床和代谢特征
- 批准号:
9218590 - 财政年份:2016
- 资助金额:
$ 46.16万 - 项目类别:
Clinical and Metabolic Signature of Recovered Myocardium in Human Heart Failure
人类心力衰竭恢复心肌的临床和代谢特征
- 批准号:
10066362 - 财政年份:2016
- 资助金额:
$ 46.16万 - 项目类别:
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