Chemistry of Life Processes Predoctoral Training Program

生命过程化学博士前培训项目

• 批准号: 10628231
• 负责人: NEIL L KELLEHER
• 金额: $ 37.14万
• 依托单位: NORTHWESTERN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10628231
• 关键词: Chemistry; Life; Process; Training Programs; pre-doctoral

PROJECT SUMMARY/ABSTRACT The complex problems encountered across length and time scales in treating disease require a broad repertoire of skills along with the capacity to harness teams possessing a range of diverse expertise to advance the discovery of new therapeutics and diagnostics. To address the pressing public health needs of the 21st century, the next generation of researchers must be able to think and communicate in a common language that spans chemistry and biology. The mission of the proposed Chemistry of Life Processes (CLP) Predoctoral Training Program at Northwestern University is to recruit, train and advance a diverse cohort of students who are prepared to lead the next wave of innovation and discovery at the interface of chemistry and biology. The CLP Training Program will address multiple dimensions of the training ecosystem and is aligned with NIGMS goals for predoctoral training: student-centered skills acquisition, trainee wellness and retention, mentor development, diversity, equity and inclusion, and assessment and improvement. The CLP Program will provide students with the opportunity to integrate graduate studies in chemistry and the life sciences to a degree beyond that of any training program at Northwestern University. The program is built upon the highly collaborative research programs of 52 mentors with extensive expertise in the areas of drug development, diagnostics, biomimetic molecules, and potential molecular targets for therapeutic intervention. The depth and breadth of its coursework requirements, novel immersive cross-disciplinary lab experience, and unique mentoring structure, coupled with a strong shared training environment, set this program apart from other Northwestern biomedical training programs. The CLP Training Program also provides an intense focus on career development through activities and programs that will expose trainees to alternative career pathways, facilitate networking with potential mentors, and foster key competencies in communications, resume development, and leadership. The evidence-based training methods and approaches developed by the CLP Program will be shared with graduate programs at Northwestern and across the country with the goal of maximizing the impact of program innovations and contributing to the development of 21st century graduate STEM education. This application requests support for 8 slots/year (Year 1; 7 slots), for a total of 39 slots over 5 years to create a vibrant cohort of peers with a common identity. Trainees are appointed to the grant starting in the fall of their second year and are supported throughout their second and third years of graduate education. Ten additional students will be supported by one-year university fellowships, enabling the participation of well-qualified and diverse international students. The program deploys a team-based approach to program leadership that leverages the unique expertise of its members and the administrative capabilities of the Chemistry of Life Processes Institute to enhance program development, assessment and evaluation, and training.

项目概要/摘要 治疗疾病时遇到的跨长度和时间尺度的复杂问题需要广泛的手段 的技能以及利用拥有各种不同专业知识的团队来推进 发现新的治疗方法和诊断方法。为满足21世纪紧迫的公共卫生需求， 下一代研究人员必须能够使用跨越不同领域的共同语言进行思考和交流 化学和生物学。拟议的生命过程化学（CLP）博士前培训的使命 西北大学的计划是招募、培训和培养多元化的学生，他们 准备引领化学和生物学交叉领域的下一波创新和发现浪潮。 CLP 培训计划将解决培训生态系统的多个维度，并与 NIGMS 保持一致 博士前培训的目标：以学生为中心的技能获取、学员健康和保留、导师 发展、多样性、公平和包容以及评估和改进。 CLP 计划将 为学生提供将化学和生命科学研究生课程整合到学位中的机会 超出了西北大学的任何培训计划。该计划建立在高度协作的基础上 由 52 名导师组成的研究项目，他们在药物开发、诊断、 仿生分子和治疗干预的潜在分子靶点。其深度和广度 课程作业要求、新颖的沉浸式跨学科实验室体验以及独特的指导结构， 加上强大的共享培训环境，使该项目有别于其他西北生物医学项目 培训计划。 CLP 培训计划还通过以下方式重点关注职业发展： 活动和计划将使受训者接触替代职业道路，促进与 潜在的导师，并培养沟通、简历发展和领导力方面的关键能力。这 CLP 计划开发的循证培训方法和途径将与毕业生分享 西北大学和全国各地的项目，目标是最大限度地发挥项目创新的影响 为21世纪研究​​生STEM教育的发展做出贡献。 此应用程序请求支持每年 8 个插槽（第 1 年；7 个插槽），5 年内总共 39 个插槽，以创建 具有共同身份的充满活力的同龄人群体。受训者从秋季开始被指定获得补助金 第二年，并在​​研究生教育的第二年和第三年得到支持。另外十个 学生将获得为期一年的大学奖学金的支持，使合格的和 多样化的国际学生。该计划部署了基于团队的计划领导方法， 利用其成员的独特专业知识和生命化学的管理能力 流程研究所旨在加强项目开发、评估和评估以及培训。