Cross-Species Multidisciplinary Training in Alcohol Research

酒精研究的跨物种多学科培训

• 批准号: 10628897
• 负责人: MICHAEL F MILES
• 金额: $ 38.83万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10628897
• 关键词: Training; alcohol research; multidisciplinary

This revised application proposes a new T32 Institutional National Research Service Award with five years of support to fund Cross-Species Multidisciplinary Training in Alcohol Research, comprising four pre-doctoral and two postdoctoral trainees. Virginia Commonwealth University (VCU) has a history of excellence in the alcohol and drug abuse fields, ranking 7th nationally in currently active NIAAA awards (n=36). Major existing research or training funding include: 80 NIDA or NIAAA currently funded projects, NIAAA P50 supported VCU Alcohol Research Center (VCU-ARC), 12 individual F-awards to VCU trainees (7 NIAAA, 5 NIDA), NIDA T32- supported training program now in its 46th year of continuous funding, NIMH T32 training program funded for over 20 years, and a recently funded Medical Scientist Training Program T32. A focal point for alcohol research at VCU is the VCU Alcohol Research Center (VCU-ARC), now in its 12th year of NIAAA support with P50 funding renewed in 2020. VCU-ARC pursues an integrated cross-species program of genetic, genomic, behavioral and molecular studies to identify genes, gene networks and genetic variants contributing to risk and mechanisms of alcohol use disorder (AUD). VCU-ARC and the overall excellence in alcohol research at VCU make this a fertile training environment across multiple VCU departments or institutes. These include: the Virginia Institute for Psychiatric and Behavioral Genetics (VIPBG) and the Departments of Pharmacology & Toxicology, Human and Molecular Genetics, Psychology, Psychiatry, Internal Medicine and the Program in Neuroscience. The cross-species academic scope will include a 2 year, monthly Foundations of Alcohol Research lecture series, monthly research seminars in VCU ARC, a trainee-led alcohol research journal club, rigorous departmental-specific core courses and advanced electives, a high level of collaboration among mentors to include reciprocal service on thesis committees, multiple excellent seminar series, and required attendance at national or international alcohol research meetings. Multiple active VCU initiatives will increase diversity of trainees, augment retention of under-represented minority faculty and enhance mentor training. Specific major program strengths include: i) broad cross-species expertise of faculty in behavioral pharmacology, psychiatry, genetics, neuroscience, statistics, neuroimaging, data science and psychology; ii) highly productive research environment with accomplished, well-funded faculty; iii) extensive experience and excellent track record of a diverse faculty in training at this level; iv) access to large, informative datasets collected at VCU; v) instruction in responsible conduct of research utilizing an innovative text from a VCU expert in this field; and vi) a unique atmosphere and strong track record at VCU for support of diversity with multiple funded programs for such efforts. This training program thus offers a broad-based, cross-species training in alcohol research in an environment of research excellence and respect for diversity.

这项修订后的申请提出了一个新的T32机构国家研究服务奖，为期五年， 支持资助酒精研究跨物种多学科培训，包括四个博士前和 两名博士后实习生。弗吉尼亚联邦大学（VCU）在酒精方面有着卓越的历史， 和药物滥用领域，在目前活跃的NIAAA奖项中排名第七（n=36）。现有主要研究 或培训资金包括：80 NIDA或NIAAA目前资助的项目，NIAAA P50支持VCU酒精 研究中心（VCU-ARC），12名VCU学员获得F-奖（7名NIAAA，5名NIDA），NIDA T32- 支持的培训计划，现在在其连续资助的第46年，NIMH T32培训计划资助， 20多年来，以及最近资助的医学科学家培训计划T32。酒精的焦点 VCU的研究是VCU酒精研究中心（VCU-ARC），现在是NIAAA支持的第12个年头， 2020年，P50融资计划再次启动。VCU-ARC追求遗传，基因组， 行为和分子研究，以确定导致风险的基因、基因网络和遗传变异， 酒精使用障碍（AUD）。VCU-ARC和VCU酒精研究的整体卓越性 使之成为跨多个VCU部门或研究所的肥沃的培训环境。这些措施包括： 弗吉尼亚精神病学和行为遗传学研究所（VIPBG）和药理学和 毒理学、人类和分子遗传学、心理学、精神病学、内科学和 神经科学跨物种的学术范围将包括2年，每月酒精基础 研究讲座系列，每月在VCU ARC，一个受训者领导的酒精研究杂志俱乐部研究研讨会， 严格的部门特定的核心课程和先进的选修课，之间的高水平合作 导师包括论文委员会的互惠服务，多个优秀的研讨会系列，并要求 参加国家或国际酒精研究会议。多个积极的自愿捐助单位举措将增加 学员的多样性，增加代表性不足的少数民族教师的保留，并加强导师培训。 具体的主要计划优势包括：i）教师在行为方面的广泛的跨物种专业知识 药理学、精神病学、遗传学、神经科学、统计学、神经影像学、数据科学和心理学; ii） 高生产力的研究环境与成就，资金充足的教师; iii）丰富的经验， 在这一级别培训的多样化教师的良好记录; iv）访问大型，信息丰富的数据集 在VCU收集; v）利用VCU的创新文本进行负责任的研究指导 在这一领域的专家;和六）在VCU支持多样性的独特氛围和良好的记录， 多个资助项目的支持。因此，这项培训计划提供了一个基础广泛的，跨物种的 在卓越的研究和尊重多样性的环境中进行酒精研究培训。