Physician Scientist Training in Age-Related Diseases

年龄相关疾病的医师科学家培训

• 批准号: 10627823
• 负责人: Daniel Robert Goldstein
• 金额: $ 60.76万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627823
• 关键词: Disease; Physicians; Scientist; Training; age related

ABSTRACT The goal of this new T32 post-doctoral training grant is to train exceptional physician-scientists for independent careers in age-related conditions. We will recruit physician-scientist trainees at the completion of clinical training and before the initiation of their independent research career. Given the growing number of older adults globally, the health-related issues of older adults will dominate the health care landscape. Physician-scientists are well poised to conduct translational research relevant to the older population as they can appreciate the clinical implications of pre-clinical research and have a unique ability to identify areas of research likely to have a substantial impact on clinical care. University of Michigan (UM) is uniquely positioned to train promising physician-scientists in age-related research as UM has robust programs in geroscience/biology of aging, geriatrics, clinical medicine and health policy research. To train physician-scientists in translational medicine in age-related conditions, we will include mentors that represent the spectrum of translational medical research from preclinical research, through to research in healthy and diseased human subjects (i.e., translational), to public policy and population health. The Director (Dr. Mody) and the two Co-Directors (Drs. Goldstein and Min) of this program are all physician- scientists who examine various aspects of age-related conditions across this translational research spectrum. Dr. Mody is a clinical interventionalist who has active collaborations with investigators who conduct basic genomic research to scientists in healthcare research policy. Dr. Goldstein examines how aging impacts inflammation by employing pre-clinical models of atherosclerosis, influenza viral infection, and organ transplantation. Dr. Min is a health services outcomes researcher with expertise in linking quality measures and quality improvement with clinical outcomes. Our training program includes faculty preceptors in each of the pre-clinical, translational and public policy domains. In addition to the individual expertise of the faculty, our program also will leverage several successful programs at UM including: The University of Michigan Older Americans Independence Center, the Michigan Institute for Clinical and Health Research, Biology of Aging, Institute for Healthcare Policy and Research, Michigan Biology of Cardiovascular Aging and Institute for Social Research. We expect that our new training program will lead to a cadre of outstandingly trained young physician-scientists who will pursue cutting-edge translational research in age-related conditions and themselves become mentors and leaders in the field.

抽象的 这项新的 T32 博士后培训补助金的目标是培养杰出的医师科学家 在与年龄相关的条件下独立从事职业。我们将在以下机构招募医师科学家实习生 完成临床培训并开始独立研究生涯之前。鉴于 全球老年人数量不断增加，老年人的健康相关问题将主导健康 关心风景。医生科学家已做好准备进行与老年人相关的转化研究 人群，因为他们能够理解临床前研究的临床意义并具有独特的能力 确定可能对临床护理产生重大影响的研究领域。密歇根大学 （UM）具有独特的优势，可以在与年龄相关的研究中培养有前途的医师科学家，因为 UM 已 老年科学/衰老生物学、老年病学、临床医学和卫生政策研究方面的强有力的项目。 为了培训医师科学家在与年龄相关的情况下进行转化医学，我们将包括导师 代表了从临床前研究到研究的转化医学研究范围 在健康和患病的人类受试者中（即转化），公共政策和人口健康。这 该项目的主任（Mody 博士）和两位联合主任（Goldstein 博士和 Min 博士）都是医生- 在这项转化研究中检查与年龄相关的状况的各个方面的科学家 光谱。 Mody 博士是一名临床介入医生，与以下研究人员积极合作 向医疗保健研究政策领域的科学家进行基础基因组研究。戈尔茨坦博士研究了如何 衰老通过采用动脉粥样硬化、流感病毒感染、 和器官移植。 Min 博士是一名健康服务成果研究员，在将 质量措施和质量改进与临床结果。我们的培训计划包括教师 每个临床前、转化和公共政策领域的导师。除了个人之外 凭借教师的专业知识，我们的项目还将利用密歇根大学的几个成功项目，包括： 密歇根大学美国老年人独立中心、密歇根临床和医学研究所 健康研究，衰老生物学，医疗保健政策与研究所，密歇根生物学 心血管衰老和社会研究所。我们期望我们的新培训计划将引领 培养一批训练有素的年轻医师科学家，他们将追求尖端的转化 与年龄相关的条件的研究和他们自己成为该领域的导师和领导者。

项目成果

Rate of Emergency Lower Extremity Amputations in the United States Among Medicare Beneficiaries.

美国医疗保险受益人紧急下肢截肢率。

• DOI: 10.1097/sla.0000000000006105
• 发表时间: 2024
• 期刊: Annals of surgery
• 影响因子: 9
• 作者: Dualeh,ShukriHA;Powell,ChloeA;Kunnath,Nicholas;Corriere,MatthewA;Ibrahim,AndrewM
• 通讯作者: Ibrahim,AndrewM

Disparities in unplanned surgery amongst medicare beneficiaries.

医疗保险受益人之间计划外手术的差异。

• DOI: 10.1016/j.amjsurg.2022.08.018
• 发表时间: 2022
• 期刊: American journal of surgery
• 影响因子: 3
• 作者: Valbuena,ValeriaSM;Dualeh,ShukriHA;Kunnath,Nicholas;Dimick,JustinB;Ibrahim,AndrewM
• 通讯作者: Ibrahim,AndrewM

Characterizing patient-reported claudication treatment goals to support patient-centered treatment selection and measurement strategies.

描述患者报告的跛行治疗目标，以支持以患者为中心的治疗选择和测量策略。

• DOI: 10.1016/j.jvs.2022.09.002
• 发表时间: 2022
• 期刊: Journal of vascular surgery
• 影响因子: 4.3
• 作者: Powell,ChloéA;Kim,GloriaY;Edwards,SydneyN;Aalami,Oliver;Treat-Jacobson,Diane;Byrnes,MaryE;Osborne,NicholasH;Corriere,MatthewA
• 通讯作者: Corriere,MatthewA