Physician Scientist Training in Age-Related Diseases

年龄相关疾病的医师科学家培训

• 批准号: 10425464
• 负责人: Daniel Robert Goldstein
• 金额: $ 59.34万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10425464
• 关键词: Disease; Physicians; Scientist; Training; age related

ABSTRACT The goal of this new T32 post-doctoral training grant is to train exceptional physician-scientists for independent careers in age-related conditions. We will recruit physician-scientist trainees at the completion of clinical training and before the initiation of their independent research career. Given the growing number of older adults globally, the health-related issues of older adults will dominate the health care landscape. Physician-scientists are well poised to conduct translational research relevant to the older population as they can appreciate the clinical implications of pre-clinical research and have a unique ability to identify areas of research likely to have a substantial impact on clinical care. University of Michigan (UM) is uniquely positioned to train promising physician-scientists in age-related research as UM has robust programs in geroscience/biology of aging, geriatrics, clinical medicine and health policy research. To train physician-scientists in translational medicine in age-related conditions, we will include mentors that represent the spectrum of translational medical research from preclinical research, through to research in healthy and diseased human subjects (i.e., translational), to public policy and population health. The Director (Dr. Mody) and the two Co-Directors (Drs. Goldstein and Min) of this program are all physician- scientists who examine various aspects of age-related conditions across this translational research spectrum. Dr. Mody is a clinical interventionalist who has active collaborations with investigators who conduct basic genomic research to scientists in healthcare research policy. Dr. Goldstein examines how aging impacts inflammation by employing pre-clinical models of atherosclerosis, influenza viral infection, and organ transplantation. Dr. Min is a health services outcomes researcher with expertise in linking quality measures and quality improvement with clinical outcomes. Our training program includes faculty preceptors in each of the pre-clinical, translational and public policy domains. In addition to the individual expertise of the faculty, our program also will leverage several successful programs at UM including: The University of Michigan Older Americans Independence Center, the Michigan Institute for Clinical and Health Research, Biology of Aging, Institute for Healthcare Policy and Research, Michigan Biology of Cardiovascular Aging and Institute for Social Research. We expect that our new training program will lead to a cadre of outstandingly trained young physician-scientists who will pursue cutting-edge translational research in age-related conditions and themselves become mentors and leaders in the field.

抽象的 这项新的T32博士后培训补助金的目标是培训杰出的医师科学家 与年龄有关的条件下的独立职业。我们将在 完成临床培训和启动独立研究职业之前。鉴于 全球越来越多的老年人数量，老年人与健康相关的问题将主导健康 护理景观。医师科学家们有很好的准备进行与老年人相关的转化研究 人口可以欣赏临床前研究的临床意义，并且具有独特的能力 确定可能对临床护理产生重大影响的研究领域。密歇根大学 （UM）独特地定位于训练有前途的医师科学家在与年龄有关的研究中，因为UM 衰老，老年医学，临床医学和卫生政策研究中的Geroscience/生物学方面的强大计划。 要在与年龄相关的情况下培训转化医学的医师科学家，我们将包括导师 这代表了从临床前研究到研究的转化医学研究的范围 在健康和患病的人类受试者（即翻译）中，到公共政策和人口健康。这 该计划的董事（Mody博士）和该计划的两个联合导演（Goldstein和Min）都是医师 - 在这项翻译研究中研究与年龄相关条件的各个方面的科学家 光谱。 Mody博士是一位临床介入主义者，他与调查人员有积极的合作 对医疗保健研究政策的科学家进行基本基因组研究。戈德斯坦博士研究了如何 衰老通过采用动脉粥样硬化，流感病毒感染的临床前模型来影响炎症， 和器官移植。 Min博士是一名健康服务成果研究人员，具有链接方面的专业知识 通过临床结果进行质量措施和质量改进。我们的培训计划包括教师 每个临床前，翻译和公共政策领域中的受体。除了个人 教师的专业知识，我们的计划还将利用UM的几个成功计划，包括： 密歇根大学美国人独立中心，密歇根州临床研究所 健康研究，衰老生物学，医疗保健政策研究所，密歇根生物学 心血管衰老和社会研究研究所。我们希望我们的新培训计划将领导 到一群受过培训的年轻医师科学家的干部，他们将追求尖端的翻译 与年龄有关的条件进行研究，并自己成为该领域的导师和领导者。