Behavioral Parenting Skills as a Novel Target for Improving Pediatric Medication Adherence

摘要 本附录的家长补助金(R01CA258337-01A1)侧重于父母教养之间的关系 诊断为急性淋巴细胞白血病(ALL)的幼儿的技能和用药依从性 最常见的儿科癌症。父母的任务是每天给口服化疗的药物 家，一种以亲子冲突、后勤困难和痛苦为标志的经历。为了 制定干预措施，最大限度地减少成功用药的障碍，关键是要了解 父母在给儿童癌症患者在家用药方面的技能、行为和经验。其中之一 这项由父母资助的研究的目的是通过视频直接观察用药情况 在家中记录，以收集客观数据，以表征日常的具体育儿经历 以及影响幼儿用药的插曲水平。对录制的视频的初步审查 对父母用药的直接观察表明有机会增加现有的 具有新开发的定性编码方案的定量编码方案。这个职位的候选人 补丁将受益于通过以下方式扩大她在照料科学方面的现有研究专长的机会 创建一种定性编码方案，以捕获有关 家庭环境。本补充的候选人还将通过分析在父项目的基础上 父母的社会人口学数据和给药之间的联系，以便确定 服药依从性结果差异的潜在模式，从而有助于她加强 她在差异研究方面的经验。最后，为了实现候选人扩大她的范围的目标 在健康素养方面的专业知识，她将扩展家长项目的目标，将父母健康素养视为 通过对健康素养进行额外分析，了解服药依从性的潜在相关性 变量来确定与父母照顾者的社会人口统计特征的潜在关联。调查结果来自 这些活动将填补关于可修改因素(照顾者行为和健康素养)的知识空白 技能)，可以通过有针对性的干预措施来解决，以改善患者结局并缩小差异。

Abstract This parent grant (R01CA258337-01A1) for this supplement focuses on the relationship between parenting skills and medication adherence in young children diagnosed with acute lymphoblastic leukemia (ALL), the most common pediatric cancer. Parents are tasked with giving daily medications for oral chemotherapy at home, an experience that can be marked by parent-child conflict, logistical difficulties, and distress. In order to develop an intervention to minimize barriers to successful medication administration, it is critical to understand parental skills, behaviors, and experiences with giving pediatric cancer patients medication at-home. One of the aims of this parent grant-funded study uses direct observation of medication administration via video recording in the home to collect objective data to characterize the specific parenting experiences at the daily and episode levels that shape medication administration in young children. Initial reviews of video-recorded direct observations of parents administering medications point to an opportunity to augment the existing quantitative coding schemes with newly developed qualitative coding schemes. The candidate for this supplement will benefit from the opportunity to expand her existing research expertise in caregiving science by creating a qualitative coding scheme that captures nuanced contextual data about medication administration in the home setting. The candidate for this supplement will also build on the parent project by analyzing associations between parents' sociodemographic data and medication administration in order to identify potential patterns of disparities in medication adherence outcomes, thus contributing to her goal to strengthen her experience in disparities research. Finally, in order to fulfill the candidate's goal of broadening her expertise in health literacy, she will extend the parent project's aim of considering parental health literacy as a potential correlate of medication adherence experiences by conducting additional analysis of the health literacy variable to identify potential associations with parental caregiver's sociodemographic traits. Findings from these activities will fill gaps in knowledge about modifiable factors (caregiver behaviors and health literacy skills) that can be addressed via targeted interventions to improve patient outcomes and mitigate disparities.