High reach, multi-level digital intervention for Pregnancy-Related and -Associated Morbidity and Mortality (PRAMM) Disparities
针对妊娠相关和相关发病率和死亡率 (PRAMM) 差异的高覆盖范围、多层次数字干预
基本信息
- 批准号:10755550
- 负责人:
- 金额:$ 74.91万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-08-17 至 2030-07-31
- 项目状态:未结题
- 来源:
- 关键词:Abnormal coordinationAddressAdoptedAwarenessBehavioralBirthBirth RecordsBlack PopulationsBlack raceCessation of lifeClinicCollaborationsColorCommunitiesCommunity Health AidesCountryDataData SetDevelopmentDisparityEarly identificationElementsEnrollmentEnsureFamily memberFeedbackGeographyHealthHealth PersonnelHealth Services AccessibilityHome visitationIncomeIndividualInterventionKnowledgeLife StyleLinkManualsMaternal HealthMaternal MortalityMeasuresMediationMedicaidMental DepressionMental HealthMichiganMorbidity - disease rateNot Hispanic or LatinoOutcomeParticipantPatientsPersonsPostpartum PeriodPregnancyPregnancy RatePrimary CarePrivatizationProviderRacial EquityRecommendationResearchResearch PersonnelResourcesRiskRisk FactorsRuralSamplingSecureServicesSiteSocial supportStructureSupport SystemSymptomsTechnologyTextTranslatingantenatalantenatal carebrief motivational interventioncheckup examinationcluster randomized designcommunity-level factorcost effectivecost effectivenessdesigndigitaldigital interventiondisparities in morbidityefficacy testingflexibilityhealth care settingsimplicit biasimprovedindexingineffective therapiesinnovationmaternal morbiditymortalitymortality disparitymortality risknovelopen sourcepartner violencepeople of colorpregnantprimary outcomeprogramsprovider communicationprovider factorsrandomized trialresidencerural areascale upscreeningsecondary outcomeservice providerssocialsocial stigmasubstance useunderserved rural areaurban areaurban residence
项目摘要
Rates of pregnancy-associated and related morbidity and mortality (PRAMM) are far higher in the U.S. than in
any other high-income country, particularly in rural areas and among non-Hispanic (NH) Black birthing people.
Technology has clear potential for reduction of PRAMM by providing screening, tailored digital content,
and connection to live assistance. Digital approaches also provide tremendous scalability and potential for
long-term optimization. Finally, technology that is sufficiently flexible and easy to use—as is the platform used in
this project—can also support deep community input through direct content creation. The proposed study builds
upon an existing app (the Pregnancy Checkup) developed by project PI Ondersma, already integrated with
antenatal services throughout Michigan, that provides universal digital screening for health risks, a brief
motivational intervention, and referral to services. The proposed project will create the Pregnancy Checkup-
PRAMM (PC-PRAMM) by extending the Pregnancy Checkup in two ways: (1) adding elements to address key
determinants of PRAMM risks at four distinct levels (individual, support system, provider, and community), with
further optimization to address the needs of Black pregnant people and those residing in underserved rural areas;
and (2) providing pregnant participants with immediate and secure “live chat” text access to a Community Health
Worker who can facilitate warm handoffs to local services. Development of PC-PRAMM will use an innovative
community partnered approach to co-creating app content. The PC-PRAMM will target known preventable
determinants of PRAMM at four levels throughout pregnancy and the first year postpartum. Our first specific
aim is to collaborate with pregnant and postpartum people (including people of color and those from
rural areas), healthcare providers, family members, and researchers to develop the PC-PRAMM, including
a manual for CHWs providing live chat assistance and facilitating engagement in services. Our second specific
aim is to evaluate PC-PRAMM effects using a cluster randomized design in 10 geographically and
demographically diverse antenatal care clinics throughout Michigan (N = 500 participants receiving Medicaid
and enrolled at less than 20 weeks gestation). We will measure change on an index of PRAMM risk factors
directly targeted by the PC-PRAMM (e.g., substance use, treatment-seeking, partner violence, early warning
sign awareness, mental health); total PRAMM among trial participants through 1 year postpartum as measured
using a pre-existing linked dataset of Medicaid claims, deaths, birth records, and primary care program data,
and disparities in both measures. This innovative community-engaged trial will translate key findings from
PRAMM research into a technology-driven intervention with strong potential for cost-effective dissemination. If
supported, this approach could provide a highly scalable approach to PRAMM reduction, particularly among
Black people and in rural areas. Further, the novel open-source platform on which the PC-PRAMM is built would
allow long-term optimization and adaptation based on new findings, quality improvement, and regional needs.
美国的妊娠相关和相关发病率和死亡率(PRAMM)远高于美国。
任何其他高收入国家,特别是在农村地区和非西班牙裔(NH)黑人生育人群中。
技术通过提供筛选、定制的数字内容,
和现场援助的联系。数字方法还提供了巨大的可扩展性和潜力,
长期优化。最后,足够灵活且易于使用的技术--就像中使用的平台一样
该项目还可以通过直接内容创建来支持深度社区输入。该研究建立了
基于PI Ondersma项目开发的现有应用程序(妊娠检查),该应用程序已与
整个密歇根州的产前服务,提供普遍的数字筛查健康风险,一个简短的
动机干预和转介服务。该项目将建立一个怀孕检查-
PRAMM(PC-PRAMM)通过两种方式扩展妊娠检查:(1)添加元素以解决关键问题
PRAMM风险在四个不同层面(个人,支持系统,供应商和社区)的决定因素,
进一步优化,以满足黑人孕妇和居住在服务不足的农村地区的人的需求;
和(2)为怀孕的参与者提供立即和安全的“实时聊天”文本访问社区健康
能为当地服务提供温暖的工作人员。PC-PRAMM的开发将采用创新的
社区合作的方法来共同创建应用程序内容。PC-PRAMM将针对已知可预防的
在整个怀孕期间和产后第一年的四个水平的PRAMM的决定因素。我们的第一个具体
目的是与怀孕和产后的人(包括有色人种和来自
农村地区),医疗保健提供者,家庭成员和研究人员开发PC-PRAMM,包括
为提供实时聊天帮助和促进服务参与的CHW提供的手册。第二个具体
目的是评估PC-PRAMM的影响,使用随机分组设计,在10个地理和
密歇根州各地人口结构多样化的产前护理诊所(N = 500名接受医疗补助的参与者
并在妊娠少于20周时登记)。我们将衡量PRAMM风险因素指数的变化
被PC-PRAMM直接瞄准(例如,药物使用、寻求治疗、伴侣暴力、预警
体征意识、心理健康);试验参与者产后1年内的总PRAMM,
使用预先存在的医疗补助索赔、死亡、出生记录和初级保健计划数据的链接数据集,
这两种措施的差距。这项创新的社区参与试验将把关键发现转化为
PRAMM研究成为一种技术驱动的干预措施,具有很大的成本效益传播潜力。如果
支持,这种方法可以提供一个高度可扩展的方法来减少PRAMM,特别是在
黑人和农村地区。此外,构建PC-PRAMM的新型开源平台将
允许根据新发现、质量改进和区域需求进行长期优化和调整。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Claire E Margerison其他文献
Claire E Margerison的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Claire E Margerison', 18)}}的其他基金
Training program addressing the multilevel factors that affect pregnancy-related and pregnancy-associated morbidity and mortality disparities
针对影响妊娠相关发病率和死亡率差异的多层次因素的培训计划
- 批准号:
10755553 - 财政年份:2023
- 资助金额:
$ 74.91万 - 项目类别:
Administrative Supplement to Policy Change and Women's Health
政策变化和妇女健康的行政补充
- 批准号:
10194963 - 财政年份:2020
- 资助金额:
$ 74.91万 - 项目类别:
Pregnancy and beyond: windows into disparities in women's cardiovascular health
怀孕及以后:了解女性心血管健康差异的窗口
- 批准号:
9096667 - 财政年份:2015
- 资助金额:
$ 74.91万 - 项目类别:
相似海外基金
Rational design of rapidly translatable, highly antigenic and novel recombinant immunogens to address deficiencies of current snakebite treatments
合理设计可快速翻译、高抗原性和新型重组免疫原,以解决当前蛇咬伤治疗的缺陷
- 批准号:
MR/S03398X/2 - 财政年份:2024
- 资助金额:
$ 74.91万 - 项目类别:
Fellowship
CAREER: FEAST (Food Ecosystems And circularity for Sustainable Transformation) framework to address Hidden Hunger
职业:FEAST(食品生态系统和可持续转型循环)框架解决隐性饥饿
- 批准号:
2338423 - 财政年份:2024
- 资助金额:
$ 74.91万 - 项目类别:
Continuing Grant
Re-thinking drug nanocrystals as highly loaded vectors to address key unmet therapeutic challenges
重新思考药物纳米晶体作为高负载载体以解决关键的未满足的治疗挑战
- 批准号:
EP/Y001486/1 - 财政年份:2024
- 资助金额:
$ 74.91万 - 项目类别:
Research Grant
Metrology to address ion suppression in multimodal mass spectrometry imaging with application in oncology
计量学解决多模态质谱成像中的离子抑制问题及其在肿瘤学中的应用
- 批准号:
MR/X03657X/1 - 财政年份:2024
- 资助金额:
$ 74.91万 - 项目类别:
Fellowship
CRII: SHF: A Novel Address Translation Architecture for Virtualized Clouds
CRII:SHF:一种用于虚拟化云的新型地址转换架构
- 批准号:
2348066 - 财政年份:2024
- 资助金额:
$ 74.91万 - 项目类别:
Standard Grant
The Abundance Project: Enhancing Cultural & Green Inclusion in Social Prescribing in Southwest London to Address Ethnic Inequalities in Mental Health
丰富项目:增强文化
- 批准号:
AH/Z505481/1 - 财政年份:2024
- 资助金额:
$ 74.91万 - 项目类别:
Research Grant
ERAMET - Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
ERAMET - 快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
- 批准号:
10107647 - 财政年份:2024
- 资助金额:
$ 74.91万 - 项目类别:
EU-Funded
BIORETS: Convergence Research Experiences for Teachers in Synthetic and Systems Biology to Address Challenges in Food, Health, Energy, and Environment
BIORETS:合成和系统生物学教师的融合研究经验,以应对食品、健康、能源和环境方面的挑战
- 批准号:
2341402 - 财政年份:2024
- 资助金额:
$ 74.91万 - 项目类别:
Standard Grant
Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
- 批准号:
10106221 - 财政年份:2024
- 资助金额:
$ 74.91万 - 项目类别:
EU-Funded
Recite: Building Research by Communities to Address Inequities through Expression
背诵:社区开展研究,通过表达解决不平等问题
- 批准号:
AH/Z505341/1 - 财政年份:2024
- 资助金额:
$ 74.91万 - 项目类别:
Research Grant