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University of Iowa Institute for Clinical and Translational Science

爱荷华大学临床与转化科学研究所

基本信息

批准号：
10622212
负责人：
Marlan R Hansen
金额：
$ 403.08万
依托单位：
UNIVERSITY OF IOWA
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-04-01 至 2030-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10622212
关键词：
Acceleration Adoption Affect Age Ally Automobile Driving Basic Science Biomedical Research Caring Clinic Clinical Clinical Research Clinical Sciences Collaborations Communities Community Practice Computerized Medical Record Data Data Collection Development Disease Outcome Diverse Workforce Education Environment Family Physicians Funding Genetic Geography Goals Health Health Personnel Health system Healthcare Healthcare Systems Home Human Human Subject Research Individual Informatics Infrastructure Institution Integrated Health Care Systems Intervention Iowa Learning Life Link Longevity Measurable Medical Care Team Mentors Methods Mission Modeling Outcome Patient Participation Patients Pharmacists Physicians Play Population Population Heterogeneity Process Provider Research Research Methodology Research Personnel Role Rural Rural Community Rural Population School Nursing Science Scientist Side System Technology Testing Time Training Translational Research Translations Universities Work care systems catalyst clinical care clinical implementation clinical practice clinical translation community engagement community organizations community setting data infrastructure data warehouse demographics design efficacy testing evidence base geographic barrier health care availability health care delivery health disparity implementation science improved informatics infrastructure innovation interoperability medical specialties member mobile computing multidisciplinary new technology novel novel strategies novel therapeutics population health practice-based research network precision medicine programs rural area rural disparities rural dwellers rurality social stakeholder perspectives systems research tool translational scientist underserved community virtual workforce needs

项目摘要

ABSTRACT The Institute for Clinical and Translational Science (ICTS) at the University of Iowa (UI) has three aims – (1) to promote an innovative, integrated, geographically distributed framework for conducting clinical and translational research, 2) to create new methods and tools that promote research participation, data collection, and interventions that link the clinic to the home and 3) to develop the diverse workforce needed to catalyze innovative science throughout populations. ICTS tackles large problems affecting translational science that require institutional solutions, such as transforming regulatory processes for human subjects research, developing an informatics infrastructure for integrating electronic medical record and other health care data, establishing bi-directional relationships with community organizations, and revitalizing the pipeline of well- trained clinical and translational researchers. Our overarching goal is to accelerate integration of research into clinical partnerships around the state and, through team science, bringing our basic, translational and clinical research workforce together to escalate the pace and breadth of scientific discovery to impact healthcare for the state and beyond. Iowa is a rural state, which brings special health care needs and challenges. We have used these rural considerations as a catalyst for driving our approach to clinical and translational research pushing our teams to develop strategies to engage rural populations of all ages and backgrounds and to create new approaches that overcome the geographic barriers in a rural state. We are capitalizing on our established community practice networks of family physicians, clinics, school nurses and pharmacists. We utilize mobile platforms in novel ways and will test the efficacy of these methods of engagement. As we move research to “IMpact Across Geographies using Innovation, Networks and Engagement- IMAG-INE” we have created methods to capture real-time, real-life data from the home and to correlate this environmentally specific, comprehensive data to human health research and outcomes. The ICTS is engaging with other CTSA hubs and national clinical and translational research systems to empirically test different approaches and to develop the evidence base of proven strategies for accelerating translation that can be more broadly disseminated. Though distance and rurality drive our approaches, the strategies that we develop are simply new and potentially better ways to generate broad representation and improved participation by patients, healthcare teams and academicians. Through our local, state and national collaborations, UI and the ICTS are poised to move clinical and translational discovery rapidly into healthcare practice in a variety of clinical settings.

摘要