Teaching the Genome Generation: Cultivating High School Genomics through Teacher Education

项目摘要/摘要 杰克逊实验室(JAX)提出了一项教师教育计划，名为“教授基因组一代” (TtGG)，为职前高中教师提供内容知识、教学策略和资源 需要加强学生在基因组学、生物伦理学和生物信息学方面的学习，重点是数学和 数据素养。我们的职业前发展计划将提供分子遗传学方面的指导 个性化医学，生物信息学工具的使用，结合统计和数据分析，以及讨论 围绕遗传学研究的伦理、法律和社会影响(ELSI)。与合作伙伴在 在高等教育方面，每年最多32名职前教师将参加一个实践短期课程。服务前 教师还将有机会通过教学参与和练习教授我们的课程 方法课程作业和学生教学/实习。我们的创新方法编织了三个学习 STRAINS-分子遗传学、生物信息学和生物伦理学-在下一代的背景下一起 科学标准和共同核心数学标准。TtGG团队将扩大我们内容的传播 和短期课程，通过显著增强我们的在线资源。将推出一项试点在线课程 2020年末，以及一个完整的在线计划，通过新设计的TtGG可以访问更多资源 面向公众的网站将于2022年第一季度建成并发布。评估这一政策的影响 短期课程，评估者将对任职前的教师参与者进行关于遗传学的事前和事后调查， 基因组学和生物信息学内容知识、教师自我效能感和自信心。评估者还将 进行小规模功效研究，以考察TtGG材料对学生内容的影响：a)内容 具有遗传学、基因组学和数学应用方面的知识；b)对从事基因组学有信心 概念、实验室活动和数学问题；c)对参与其他基因组学相关行为的兴趣， 包括学术和职业追求；以及d)解释如何以及为什么需要数学技能的能力 实践生命科学。通过培训职前教育工作者，TtGG将执行NIH加强 通过提高基因组和健康素养来培养未来的STEM劳动力。

PROJECT SUMMARY/ABSTRACT The Jackson Laboratory (JAX) proposes a teacher education initiative, 'Teaching the Genome Generation' (TtGG), to provide pre-service high school teachers the content knowledge, teaching strategies, and resources needed to enhance student learning in genomics, bioethics, and bioinformatics, with an emphasis on math and data literacy. Our pre-professional development program will provide instruction in the molecular genetics of personalized medicine, use of bioinformatics tools, incorporating statistics and data analysis, and discussion of the ethical, legal, and social implications (ELSI) surrounding genetics research. In collaboration with partners in higher education, up to 32 pre-service teachers per year will participate in a hands-on short course. Pre-service teachers will also have the opportunity to engage with and practice teaching our curriculum through instructional methods coursework and student teaching/internships. Our innovative approach weaves three learning strands—molecular genetics, bioinformatics and bioethics—together within the context of the Next Generation Science Standards and Common Core Math Standards. The TtGG team will expand dissemination of our content and short course through significant enhancement of our online resources. A pilot online course will be launched in late 2020, and a full online program with additional resources accessible through a newly designed TtGG public facing website will be completed and released by the first quarter of 2022. To evaluate the impact of the short course, evaluators will administer pre and post surveys to pre-service teacher participants on genetics, genomics and bioinformatics content knowledge, teacher self-efficacy, and confidence. Evaluators will also conduct small scale efficacy studies to examine the impact of the TtGG materials on students': a) content knowledge of genetics, genomics, and applications of mathematics; b) confidence engaging in genomics concepts, lab activities, and math problems; c) interest in engaging in additional genomics-related behavior, including academic and career pursuits; and d) ability to explain how and why math skills are required for practicing life sciences. By training pre-service educators, TtGG will execute on NIH's goal of strengthening the future STEM workforce through increasing genomic and health literacy.