The National Center for Interventional Biophotonic Technologies (NCIBT)
国家介入生物光子技术中心 (NCIBT)
基本信息
- 批准号:10744968
- 负责人:
- 金额:$ 6.74万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-06-20 至 2027-03-31
- 项目状态:未结题
- 来源:
- 关键词:AccelerationAcuteAddressAlgorithmsAreaBiophotonicsCardiologyCerebrovascular CirculationClinicalClinical ManagementCognitionCollaborationsCommunitiesComplementDataDecision MakingDegenerative DisorderDementiaDevelopmentDiagnosisDiffuseDiffusionDisease ManagementEducational workshopElectronic MailEngineeringEnsureEquipmentFetal healthGeneral PopulationGoalsHandHealthHeart DiseasesHigh-Risk PregnancyHumanHumanitiesImageImaging DeviceImaging TechniquesImaging technologyImmersionIndividualInfectionInstitutionIntelligenceInterventionLegal patentLinkLiteratureMalignant NeoplasmsMedicalMedical SocietiesMedical centerMedicineMetabolismMonitorNear-Infrared SpectroscopyOphthalmologyOpticsParticipantPatient-Focused OutcomesPatientsPerfusionPhysiciansProceduresProgram DevelopmentPropertyPublic HealthPublicationsResearchResearch Project GrantsResolutionSchoolsScientistServicesSourceSpectrum AnalysisSpeedStrokeStructureSurgeonSurgical OncologistSurgical OncologySystemTechnologyTherapeuticTimeTissuesTrainingTraining ProgramsTranslationsTraumaTraumatic ShockVisionVisitVisualizationWorkanalytical toolclinical applicationclinical decision-makingclinical translationcommercializationcomputerized toolsdata streamsdeep learningdesignfluorescence lifetime imagingglobal healthholistic approachimage guidedimaging modalityimaging platformimprovedindividualized medicineindustry partnerinnovationinstrumentinterestmeetingsnervous system disordernovelopen sourceoptical imagingphotonicsprecision medicineprogram disseminationprogramsresidencesocial mediasymposiumtechnology developmenttechnology trainingtumorweb site
项目摘要
PROJECT SUMMARY – Overall
The long-term goal of the National Center for Interventional Biophotonic Technologies (NCIBT) is to promote
public health by advancing a new paradigm for intraprocedural, image-guided decision making. The Center's
strategy is to advance optical spectroscopy and imaging technologies, to develop means of providing imaging
results to medical practitioners at the time, in the form, and within the context they will be most useful in guiding
decisions, and to maximize the impact of this work by involving as many scientists and physicians as possible in
developing and using these technologies. Initially, the Center will promote technological advancements of
interventional fluorescence lifetime imaging (iFLIM) and interferometric diffuse optical spectroscopy (iDOS) and
their translation into clinical use. An open-ended intraprocedural platform will incorporate them and, eventually,
complementary optical imaging technologies. Specifically, NCIBT will (1) advance scalable optical imaging
technology, built from the perspective of intelligent optical system design, to characterize tissue properties in the
most effective manner; (2) develop an intraprocedural platform that physically incorporates these technologies
and integrates the resulting imaging data, details of the procedure, and patient-specific information within AI-
based decision algorithms that guide, in real-time, therapeutic decisions, and (3) disseminate these technological
advancements to research institutions and medical centers. The significance of this project derives from its
potential for rapid advancement, catalyzed by an AI-directed holistic approach to instrument design, of its optical
imaging technologies and platform and their relevance to managing humanity's most common afflictions - cancer,
stroke, heart disease, trauma, infection, and degenerative diseases. NCIBT will ensure the national impact of
these technological advancements by creating and expanding a network of collaborative research and service
projects broadly distributed nationwide and implementing a comprehensive training and dissemination program.
Annual workshops, hand-on training sessions at national meetings, in special courses and at UC Davis,
presentations and publications will educate, train, equip and diversify potential users of NCIBT technology.
Bridging gaps between engineering and medicine and between technology development and clinical application
will ensure that the needed technologies are developed and applied clinically to improve the nation's health.
项目概要-总体
国家介入生物光子技术中心(NCIBT)的长期目标是促进
通过推进程序内图像引导决策的新范式,为公共卫生服务。该中心的
战略是推进光学光谱学和成像技术,发展提供成像的手段,
结果,医生在当时,在形式上,并在上下文中,他们将是最有用的指导
决策,并通过让尽可能多的科学家和医生参与进来,
开发和使用这些技术。该中心最初将促进技术进步,
介入荧光寿命成像(iFLIM)和干涉漫射光谱(iDOS),
转化为临床应用。一个不限成员名额的程序内平台将纳入这些建议,
互补光学成像技术。具体而言,NCIBT将(1)推进可扩展的光学成像
技术,从智能光学系统设计的角度构建,以表征
最有效的方式;(2)开发一个实际上包含这些技术的程序内平台
并将所得成像数据、手术细节和患者特定信息整合到AI中,
基于决策算法,实时指导治疗决策,以及(3)传播这些技术
研究机构和医疗中心的进步。该项目的意义在于其
在人工智能指导的仪器设计整体方法的催化下,
成像技术和平台及其与管理人类最常见的疾病-癌症,
中风、心脏病、创伤、感染和退行性疾病。NCIBT将确保国家的影响,
通过创建和扩大合作研究和服务网络,
项目在全国范围内广泛分布,并实施全面的培训和宣传方案。
年度研讨会,在国家会议上的实践培训课程,在特别课程和加州大学戴维斯分校,
演讲和出版物将教育、培训、装备NCIBT技术的潜在用户并使其多样化。
弥合工程与医学、技术开发与临床应用之间的差距
将确保所需的技术得到开发和临床应用,以改善国民健康。
项目成果
期刊论文数量(3)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Virtual tissue staining in pathology using machine learning
使用机器学习进行病理学虚拟组织染色
- DOI:10.1080/14737159.2022.2153040
- 发表时间:2022
- 期刊:
- 影响因子:5.1
- 作者:Pillar, Nir;Ozcan, Aydogan
- 通讯作者:Ozcan, Aydogan
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Griffith R. Harsh其他文献
First In-Human Intraoperative Near-Infrared Fluorescence Imaging of Glioblastoma Using Cetuximab-IRDye800: Results from a Pilot Study
- DOI:
10.1016/j.jamcollsurg.2017.07.315 - 发表时间:
2017-10-01 - 期刊:
- 影响因子:
- 作者:
Sarah E. Miller;Willemieke S. Tummers;Nutte (Tarn) Teraphongphom;Alifia J. Hasan;Robert D. Ertsey;Griffith R. Harsh;Edward D. Plowey;Gerald A. Grant;Gordon H. Li;Eben L. Rosenthal - 通讯作者:
Eben L. Rosenthal
Differential regulation of platelet-derived growth factor A and B chain messages in microvascular endothelial cells
- DOI:
10.1016/s0022-2828(87)80651-x - 发表时间:
1987-01-01 - 期刊:
- 影响因子:
- 作者:
Niel F. Starksen;Griffith R. Harsh;Verna C. Gibbs;Lewis T. Williams - 通讯作者:
Lewis T. Williams
Neurosurgical Resident Error: A Survey of U.S. Neurosurgery Residency Training Program Directors' Perceptions
- DOI:
10.1016/j.wneu.2017.10.022 - 发表时间:
2018-01-01 - 期刊:
- 影响因子:
- 作者:
Raghav Gupta;Justin M. Moore;Nimer Adeeb;Christoph J. Griessenauer;Anna M. Schneider;Chirag D. Gandhi;Griffith R. Harsh;Ajith J. Thomas;Christopher S. Ogilvy - 通讯作者:
Christopher S. Ogilvy
A multi-institutional experience with stereotactic radiosurgery for solitary brain metastases
- DOI:
10.1016/0360-3016(93)90714-7 - 发表时间:
1993-01-01 - 期刊:
- 影响因子:
- 作者:
John C. Flickinger;Douglas Kondziolka;L. Dade Lunsford;Robert J. Coffey;Michael L. Goodman;Edward G. Shaw;W. Robert Hudgins;Richard Weiner;Griffith R. Harsh;Penny K. Sneed;David A. Larson - 通讯作者:
David A. Larson
Haploinsufficiency of emNFKBIA/em reshapes the epigenome antipodal to the emIDH/em mutation and imparts disease fate in diffuse gliomas
emNFKBIA/em 的单倍体不足重塑了与 emIDH/em 突变相对的表观基因组,并赋予弥漫性胶质瘤疾病命运
- DOI:
10.1016/j.xcrm.2023.101082 - 发表时间:
2023-06-20 - 期刊:
- 影响因子:10.600
- 作者:
Markus Bredel;Lluís Espinosa;Hyunsoo Kim;Denise M. Scholtens;Joseph P. McElroy;Rajani Rajbhandari;Wei Meng;Thomas M. Kollmeyer;Tathiane M. Malta;Michael A. Quezada;Griffith R. Harsh;Teresa Lobo-Jarne;Laura Solé;Aran Merati;Surya Nagaraja;Sindhu Nair;Jaclyn J. White;Nanda K. Thudi;Jessica L. Fleming;Amy Webb;Arnab Chakravarti - 通讯作者:
Arnab Chakravarti
Griffith R. Harsh的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Griffith R. Harsh', 18)}}的其他基金
UC Davis Clinician Neuroscientist Development Program
加州大学戴维斯分校临床医生神经科学家发展计划
- 批准号:
10334321 - 财政年份:2022
- 资助金额:
$ 6.74万 - 项目类别:
UC Davis Clinician Neuroscientist Development Program
加州大学戴维斯分校临床医生神经科学家发展计划
- 批准号:
10672886 - 财政年份:2022
- 资助金额:
$ 6.74万 - 项目类别:
The National Center for Interventional Biophotonic Technologies (NCIBT)
国家介入生物光子技术中心 (NCIBT)
- 批准号:
10649445 - 财政年份:2022
- 资助金额:
$ 6.74万 - 项目类别:
The National Center for Interventional Biophotonic Technologies (NCIBT)
国家介入生物光子技术中心 (NCIBT)
- 批准号:
10424945 - 财政年份:2022
- 资助金额:
$ 6.74万 - 项目类别:
Stanford Neurosurgery Resident Research Education Program
斯坦福大学神经外科住院医师研究教育计划
- 批准号:
8628240 - 财政年份:2009
- 资助金额:
$ 6.74万 - 项目类别:
Stanford Neurosurgery Resident Research Education Program
斯坦福大学神经外科住院医师研究教育计划
- 批准号:
8234656 - 财政年份:2009
- 资助金额:
$ 6.74万 - 项目类别:
Stanford Neurosurgery Resident Research Education Program
斯坦福大学神经外科住院医师研究教育计划
- 批准号:
8230757 - 财政年份:2009
- 资助金额:
$ 6.74万 - 项目类别:
Stanford Neurosurgery Resident Research Education Program
斯坦福大学神经外科住院医师研究教育计划
- 批准号:
8435675 - 财政年份:2009
- 资助金额:
$ 6.74万 - 项目类别:
相似海外基金
Transcriptional assessment of haematopoietic differentiation to risk-stratify acute lymphoblastic leukaemia
造血分化的转录评估对急性淋巴细胞白血病的风险分层
- 批准号:
MR/Y009568/1 - 财政年份:2024
- 资助金额:
$ 6.74万 - 项目类别:
Fellowship
Combining two unique AI platforms for the discovery of novel genetic therapeutic targets & preclinical validation of synthetic biomolecules to treat Acute myeloid leukaemia (AML).
结合两个独特的人工智能平台来发现新的基因治疗靶点
- 批准号:
10090332 - 财政年份:2024
- 资助金额:
$ 6.74万 - 项目类别:
Collaborative R&D
Acute senescence: a novel host defence counteracting typhoidal Salmonella
急性衰老:对抗伤寒沙门氏菌的新型宿主防御
- 批准号:
MR/X02329X/1 - 财政年份:2024
- 资助金额:
$ 6.74万 - 项目类别:
Fellowship
Cellular Neuroinflammation in Acute Brain Injury
急性脑损伤中的细胞神经炎症
- 批准号:
MR/X021882/1 - 财政年份:2024
- 资助金额:
$ 6.74万 - 项目类别:
Research Grant
KAT2A PROTACs targetting the differentiation of blasts and leukemic stem cells for the treatment of Acute Myeloid Leukaemia
KAT2A PROTAC 靶向原始细胞和白血病干细胞的分化,用于治疗急性髓系白血病
- 批准号:
MR/X029557/1 - 财政年份:2024
- 资助金额:
$ 6.74万 - 项目类别:
Research Grant
Combining Mechanistic Modelling with Machine Learning for Diagnosis of Acute Respiratory Distress Syndrome
机械建模与机器学习相结合诊断急性呼吸窘迫综合征
- 批准号:
EP/Y003527/1 - 财政年份:2024
- 资助金额:
$ 6.74万 - 项目类别:
Research Grant
FITEAML: Functional Interrogation of Transposable Elements in Acute Myeloid Leukaemia
FITEAML:急性髓系白血病转座元件的功能研究
- 批准号:
EP/Y030338/1 - 财政年份:2024
- 资助金额:
$ 6.74万 - 项目类别:
Research Grant
STTR Phase I: Non-invasive focused ultrasound treatment to modulate the immune system for acute and chronic kidney rejection
STTR 第一期:非侵入性聚焦超声治疗调节免疫系统以治疗急性和慢性肾排斥
- 批准号:
2312694 - 财政年份:2024
- 资助金额:
$ 6.74万 - 项目类别:
Standard Grant
ロボット支援肝切除術は真に低侵襲なのか?acute phaseに着目して
机器人辅助肝切除术真的是微创吗?
- 批准号:
24K19395 - 财政年份:2024
- 资助金额:
$ 6.74万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Acute human gingivitis systems biology
人类急性牙龈炎系统生物学
- 批准号:
484000 - 财政年份:2023
- 资助金额:
$ 6.74万 - 项目类别:
Operating Grants