The National Center for Interventional Biophotonic Technologies (NCIBT)

国家介入生物光子技术中心 (NCIBT)

• 批准号: 10744968
• 负责人: Griffith R. Harsh
• 金额: $ 6.74万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-20 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10744968
• 关键词: Acceleration; Acute; Address; Algorithms; Area; Biophotonics; Cardiology; Cerebrovascular Circulation; Clinical; Clinical Management; Cognition; Collaborations; Communities; Complement; Data; Decision Making; Degenerative Disorder; Dementia; Development; Diagnosis; Diffuse; Diffusion; Disease Management; Educational workshop; Electronic Mail; Engineering; Ensure; Equipment; Fetal health; General Population; Goals; Hand; Health; Heart Diseases; High-Risk Pregnancy; Human; Humanities; Image; Imaging Device; Imaging Techniques; Imaging technology; Immersion; Individual; Infection; Institution; Intelligence; Intervention; Legal patent; Link; Literature; Malignant Neoplasms; Medical; Medical Societies; Medical center; Medicine; Metabolism; Monitor; Near-Infrared Spectroscopy; Ophthalmology; Optics; Participant; Patient-Focused Outcomes; Patients; Perfusion; Physicians; Procedures; Program Development; Property; Public Health; Publications; Research; Research Project Grants; Resolution; Schools; Scientist; Services; Source; Spectrum Analysis; Speed; Stroke; Structure; Surgeon; Surgical Oncologist; Surgical Oncology; System; Technology; Therapeutic; Time; Tissues; Training; Training Programs; Translations; Trauma; Traumatic Shock; Vision; Visit; Visualization; Work; analytical tool; clinical application; clinical decision-making; clinical translation; commercialization; computerized tools; data streams; deep learning; design; fluorescence lifetime imaging; global health; holistic approach; image guided; imaging modality; imaging platform; improved; individualized medicine; industry partner; innovation; instrument; interest; meetings; nervous system disorder; novel; open source; optical imaging; photonics; precision medicine; program dissemination; programs; residence; social media; symposium; technology development; technology training; tumor; web site

PROJECT SUMMARY – Overall The long-term goal of the National Center for Interventional Biophotonic Technologies (NCIBT) is to promote public health by advancing a new paradigm for intraprocedural, image-guided decision making. The Center's strategy is to advance optical spectroscopy and imaging technologies, to develop means of providing imaging results to medical practitioners at the time, in the form, and within the context they will be most useful in guiding decisions, and to maximize the impact of this work by involving as many scientists and physicians as possible in developing and using these technologies. Initially, the Center will promote technological advancements of interventional fluorescence lifetime imaging (iFLIM) and interferometric diffuse optical spectroscopy (iDOS) and their translation into clinical use. An open-ended intraprocedural platform will incorporate them and, eventually, complementary optical imaging technologies. Specifically, NCIBT will (1) advance scalable optical imaging technology, built from the perspective of intelligent optical system design, to characterize tissue properties in the most effective manner; (2) develop an intraprocedural platform that physically incorporates these technologies and integrates the resulting imaging data, details of the procedure, and patient-specific information within AI- based decision algorithms that guide, in real-time, therapeutic decisions, and (3) disseminate these technological advancements to research institutions and medical centers. The significance of this project derives from its potential for rapid advancement, catalyzed by an AI-directed holistic approach to instrument design, of its optical imaging technologies and platform and their relevance to managing humanity's most common afflictions - cancer, stroke, heart disease, trauma, infection, and degenerative diseases. NCIBT will ensure the national impact of these technological advancements by creating and expanding a network of collaborative research and service projects broadly distributed nationwide and implementing a comprehensive training and dissemination program. Annual workshops, hand-on training sessions at national meetings, in special courses and at UC Davis, presentations and publications will educate, train, equip and diversify potential users of NCIBT technology. Bridging gaps between engineering and medicine and between technology development and clinical application will ensure that the needed technologies are developed and applied clinically to improve the nation's health.

项目概述-整体

项目成果

Virtual tissue staining in pathology using machine learning

使用机器学习进行病理学虚拟组织染色

• DOI: 10.1080/14737159.2022.2153040
• 发表时间: 2022
• 期刊: Expert Review of Molecular Diagnostics
• 影响因子: 5.1
• 作者: Pillar, Nir;Ozcan, Aydogan
• 通讯作者: Ozcan, Aydogan