Age-related macular degeneration: A cause and a cure

年龄相关性黄斑变性：原因和治疗方法

• 批准号: nhmrc : GNT1103013
• 负责人: Prof Robyn Guymer
• 金额: $ 82.83万
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/age-related-macular-cause-cure/1346257
• 关键词: Age; related; macular; degeneration; cause

Age-related macular degeneration (AMD) is a leading cause of vision loss and there is urgent need for an intervention to slow disease progression. AMD is characterised by debris accumulation in the retina and I will investigate if loss of function in cells that should clear this debris is a critical step in the development of AMD. I will trial a novel laser intervention to slow progression of disease and use basic science techniques to investigate the mechanisms of action of the laser.

老年性黄斑变性(AMD)是导致视力丧失的主要原因，迫切需要干预措施来减缓疾病的进展。AMD的特点是视网膜碎片堆积，我将调查应该清除这些碎片的细胞功能丧失是否是AMD发展过程中的关键一步。我将尝试一种新的激光干预措施来减缓疾病的进展，并使用基础科学技术来研究激光的作用机制。