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Comparative Pathology Core-Core 4

比较病理学核心-核心4

基本信息

批准号：
10617367
负责人：
Katherine Nicole Gibson-Corley
金额：
$ 13.38万
依托单位：
UNIVERSITY OF IOWA
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
起止时间：
1998-09-30 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10617367
关键词：
Animal Disease Models Animal Experimentation Animal Experiments Animal Model Area Autopsy Board Certification Cellular Morphology Clinics and Hospitals Comparative Pathology Cystic Fibrosis Data Analyses Diagnostic Disease Equipment Experimental Designs Family suidae Ferrets Goals Histologic Histology Human Inflammation Iowa Laboratories Manuscripts Medicine Mission Modeling Morphology Mus Organ Pathologist Pathology Protocols documentation Quantitative Evaluations Research Research Personnel Resources Scanning Scientist Services Source Specimen Stains Technical Expertise Techniques Tissue Banks Tissue Sample Tissues Translational Research Translations Universities Veterinary Pathology Work Writing animal care cell type comparative cystic fibrosis mouse experience gene therapy histological specimens histotechnology instrumentation research study tissue processing

项目摘要

Abstract/Summary (Comparative Pathology Core–Core 4) The goal of the Comparative Pathology Core is to provide professional services and expertise to Center Investigators of the Cystic Fibrosis Research and Translation Core Center. To facilitate these goals the Pathology Core offers 1) technical expertise and support for histotechnology techniques from tissue processing to specialized staining (histochemical and immunohistochemical) and 2) ACVP-boarded veterinary pathologist expertise and support for morphologic, quantitative and semi-quantitative evaluation of tissues from CF pig, CF mouse and CF ferret studies. The Comparative Pathology Core will provide services to Center Investigators in a timely and efficient manner for optimal assessment of tissues. The goals of the Comparative Pathology Core are to: 1. Provide histotechnology services to the Center Investigators through CPL resources and experienced staff. 2. Assist with professional necropsy services for Center Investigators. 3. Provide veterinary pathologists services to the Center Investigators. 4. Serve as a conduit for dissemination of histologic specimens from CF pig and ferret models to researchers outside the University of Iowa.

摘要/总结（比较病理学核心-核心4）比较病理学核心的目标是为中心提供专业服务和专业知识，囊性纤维化研究和翻译核心中心的研究人员。为了实现这些目标，病理学核心提供1）技术专长和支持，从组织处理技术专业染色（组织化学和免疫组织化学）和2）ACVP注册兽医病理学家 CF猪组织形态学、定量和半定量评价的专业知识和支持，CF 小鼠和CF雪貂研究。比较病理学核心将为中心研究者提供服务，及时有效地对组织进行最佳评估。比较病理学核心的目标是： 1.通过CPL资源为中心研究者提供组织技术服务，工作人员 2.协助中心研究者的专业尸检服务。 3.为中心研究者提供兽医病理学家服务。 4.作为CF猪和雪貂模型的组织学标本传播的管道，爱荷华州大学外的研究人员。