Enhancement training for the next generation of translational Ph.D. scientists

下一代转化博士的强化培训

• 批准号: 10626596
• 负责人: Victoria Lin Bae-Jump
• 金额: $ 26.53万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-21 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10626596
• 关键词: Doctor of Philosophy; Scientist; Training; next generation

PROJECT SUMMARY/ABSTRACT The University of North Carolina at Chapel Hill (UNC) Program in Translational Medicine (PiTM) was first established in 2006 with funding support from the Howard Hughes Medical Institute and later supported by a T32 from the National Institutes of Health. The UNC PiTM is a unique program that fills unmet needs among biomedical graduate students at UNC. Unlike department- and disease-focused programs, the PiTM is cross- department, -diseases, and -disciplines, providing our trainees with a rich exposure to diverse topics in translational medicine. The primary objective of the PiTM is to train a cadre of PhD researchers with the knowledge and skills necessary to recognize, appreciate, and address clinically-relevant biological problems related to human disease from the perspective of basic science. To accomplish this goal, the PiTM trains basic science PhD students to work in multidisciplinary teams composed of scientists, physician-scientists, and clinicians, using state-of-the-art experimental approaches and patient-derived resources. The trainees have a dual (scientist/clinical) mentored experience, a rigorous clinical exposure, and blended core coursework that enhances training in translational medicine. Trainees also receive additional training to build communication and leadership skills essential for future team science and community outreach endeavors. The PiTM structure includes both funded and unfunded trainees (~10-15 matriculants each year), each with access to the same rigorous training opportunities and experiences throughout their graduate tenure. This structure enables us to maximize diversity within the PiTM and enhance the training experience. With this current application, we request support for 6 1-year slots for outstanding PiTM trainees. The PiTM has over a decade of experience in best practices training over 150 basic science PhD students, 67% female and 19% underrepresented, to perform translational research. The proposed training leverages this experience to create a unique training model for preparing the next generation of PhD researchers to effectively lead and contribute to multidisciplinary teams of translational researchers.

项目概要/摘要 北卡罗来纳大学教堂山分校 (UNC) 转化医学项目 (PiTM) 是第一个 于 2006 年在霍华德休斯医学研究所的资助下成立，后来得到了 T32 来自美国国立卫生研究院。北卡罗来纳大学 PiTM 是一个独特的项目，可以满足未满足的需求 北卡罗来纳大学生物医学研究生。与以部门和疾病为中心的计划不同，PiTM 是跨部门的 部门、疾病和学科，为我们的学员提供丰富的接触不同主题的机会 转化医学。 PiTM 的主要目标是培养一支具有以下能力的博士研究人员骨干队伍： 识别、理解和解决临床相关生物学问题所需的知识和技能 从基础科学的角度来看与人类疾病有关。为了实现这一目标，PiTM 训练了基本的 科学博士生在由科学家、医师科学家和科学家组成的多学科团队中工作 临床医生使用最先进的实验方法和患者来源的资源。学员们有一个 双重（科学家/临床）指导经验、严格的临床接触以及混合的核心课程， 加强转化医学培训。学员还接受额外的培训以建立沟通和 领导技能对于未来的团队科学和社区外展工作至关重要。 PiTM结构 包括有资助和无资助的受训者（每年约 10-15 名预科生），每个人都可以获得相同的 在整个研究生任期内提供严格的培训机会和经验。这种结构使我们能够 最大限度地提高 PiTM 内的多样性并增强培训体验。对于当前的申请，我们要求 为优秀 PiTM 学员提供 6 个为期 1 年的名额支持。 PiTM 拥有十多年的最佳经验 实践培训超过 150 名基础科学博士生（其中 67% 为女性，19% 代表性不足） 转化研究。拟议的培训利用这一经验来创建独特的培训模型 培养下一代博士研究人员有效领导多学科团队并为其做出贡献 转化研究人员。