Vermont Center on Behavior and Health

项目总结 总体规划 这项申请的首要目标是建立生物医学研究卓越中心(COBRE)第三阶段 该奖项是在佛蒙特州大学建立佛蒙特州行为与健康中心(VCBH) (UVM)作为可持续的卓越研究中心。这个多学科中心研究人际关系 个人行为(生活方式)与慢性病和过早死亡的风险之间的关系。VCBH制造 在第一阶段和第二阶段取得了相当大的进展，成为一个充满活力和可持续发展的中心。VCBH 建立了外部赠款支持和同行评议出版物的良好记录，总额为1.651亿美元 累计资助，包括向Cobre项目负责人(PLS)颁发的1830万美元奖励，以及 同行评议的期刊，包括515个将pls列为第一作者或合著者的期刊。请成功获得美国国立卫生研究院， 基金会和行业奖，如绩效指标、项目绩效指标和合作伙伴。第一阶段和第二阶段的其他显著成就 包括建立一个由NIH支持的UVM烟草监管科学中心，最初的P50奖励 它被续签为U54，两次续签了NIH T32临床成瘾研究培训奖，目前正在 31-36岁，并建立了由人权事务管理局支持的新的UVM农村成瘾中心和新的NIH T32 神经生物学成瘾研究培训奖。VCBH核心继续支持充满活力的每月讲座 系列、年度全国会议和担任同行评议期刊年度特刊的特邀编辑 以预防医学为基础的会议。VCBH与其他科布雷公司的合作继续增长， VCBH Pi Higgins博士担任两个Cobre外部咨询委员会的主席，并担任第三个委员会的成员。在……里面 第三阶段，我们建议维持VCBH的竞争力，以获得外部赠款支持和培育新的 研究和传播倡议。我们将继续指导早期职业调查人员，利用我们的 三个核心拥有强大的机构支持和广泛的覆盖范围，并围绕以下方面凝聚VCBH协作 五个科学优势领域，每个领域都有自己的工作组。一个创新的试点项目计划将是 用于支持职业生涯早期调查人员，并为当前的拨款申请生成初步数据 并培育新的研究方向。我们相信，在第三阶段的支持下，VCBH将 作为一个可持续的、有影响力的、多学科的卓越研究中心，我们处于有利的地位。

PROJECT SUMMARY Overall Plan The overarching goal of this application for a Phase 3 Center of Biomedical Research Excellence (COBRE) award is to firmly establish the Vermont Center on Behavior and Health (VCBH) at the University of Vermont (UVM) as a sustainable center of research excellence. This multidisciplinary center investigates relationships between personal behavior (lifestyle) and risk for chronic disease and premature death. VCBH made considerable progress during Phases 1 and 2 towards becoming a vibrant and sustainable center. VCBH established a strong record of external grant support and peer-reviewed publications with $165.1 million in total cumulative funding, including $18.3 million from awards to COBRE Project Leaders (PLs), and 917 articles in peer-reviewed journals, including 515 listing PLs as 1st or co-authors. PLs succeeded in obtaining NIH, foundation, and industry awards as PIs, Project PIs, and Co-Is. Other Phase 1 and 2 notable accomplishments included establishing an NIH-supported UVM Tobacco Center of Regulatory Science with an initial P50 award that was renewed as a U54, twice renewing an NIH T32 training award in clinical addictions research now in years 31-36, and establishing the new HRSA-supported UVM Center on Rural Addiction and a new NIH T32 training award in neurobiological addiction research. VCBH cores continue to support a vibrant monthly lecture series, annual national conferences, and guest editorship of an annual special issue of the peer-reviewed journal Preventive Medicine based on the conferences. VCBH collaborations with other COBREs continue to grow, with VCBH PI Dr. Higgins chairing two COBRE External Advisory Committees and serving as a member of a third. In Phase 3, we propose to sustain VCBH competitiveness in obtaining external grant support and fostering new research and dissemination initiatives. We will continue mentoring early career investigators, leveraging our three cores that have strong institutional support and broad reach, and coalescing VCBH collaborations around five areas of scientific strength, each with its own working group. An innovative Pilot Project Program will be leveraged to support early-career investigators and generate preliminary data for grant applications in current areas of strength and to foster new research directions. We are confident that with Phase 3 support, VCBH is well positioned to succeed as a sustainable, impactful, multidisciplinary center of research excellence.