Vermont Center on Behavior and Health

佛蒙特州行为与健康中心

• 批准号: 10626473
• 负责人: Stephen T Higgins
• 金额: $ 111.3万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10626473
• 关键词: Advisory Committees; Applications Grants; Area; Award; Behavior; Centers of Research Excellence; Cessation of life; Chronic Disease; Clinical; Clinical Research; Collaborations; Complex; Data; Education; Environment; Faculty; Fostering; Foundations; Funding; Funding Opportunities; Goals; Grant; Growth; Health; Health Promotion; Individual; Industry; Institution; Interdisciplinary Study; International; Intervention; Journals; Knowledge; Learning; Life Style; Medical; Mentors; Nebraska; Neurobiology; Obesity; Pattern; Peer Review; Periodicals; Personal Behavior; Pharmacological Treatment; Phase; Pilot Projects; Policies; Positioning Attribute; Preventive Medicine; Publications; Regimen; Research; Research Personnel; Risk; Risk Behaviors; Role; Rural; Schedule; Science; Scientific Advances and Accomplishments; Scientist; Series; Structure; Substance abuse problem; System; Tobacco; Training; United States Health Resources and Services Administration; United States National Institutes of Health; Universities; Vermont; Vulnerable Populations; addiction; behavior change; behavioral economics; behavioral health; brain research; career; clinical care; college; contingency management; cost effective; disorder risk; early-career faculty; evidence base; improved; innovation; lectures; member; multidisciplinary; next generation; physical inactivity; premature; programs; senior faculty; sound; substance misuse; success; symposium; working group

PROJECT SUMMARY Overall Plan The overarching goal of this application for a Phase 3 Center of Biomedical Research Excellence (COBRE) award is to firmly establish the Vermont Center on Behavior and Health (VCBH) at the University of Vermont (UVM) as a sustainable center of research excellence. This multidisciplinary center investigates relationships between personal behavior (lifestyle) and risk for chronic disease and premature death. VCBH made considerable progress during Phases 1 and 2 towards becoming a vibrant and sustainable center. VCBH established a strong record of external grant support and peer-reviewed publications with $165.1 million in total cumulative funding, including $18.3 million from awards to COBRE Project Leaders (PLs), and 917 articles in peer-reviewed journals, including 515 listing PLs as 1st or co-authors. PLs succeeded in obtaining NIH, foundation, and industry awards as PIs, Project PIs, and Co-Is. Other Phase 1 and 2 notable accomplishments included establishing an NIH-supported UVM Tobacco Center of Regulatory Science with an initial P50 award that was renewed as a U54, twice renewing an NIH T32 training award in clinical addictions research now in years 31-36, and establishing the new HRSA-supported UVM Center on Rural Addiction and a new NIH T32 training award in neurobiological addiction research. VCBH cores continue to support a vibrant monthly lecture series, annual national conferences, and guest editorship of an annual special issue of the peer-reviewed journal Preventive Medicine based on the conferences. VCBH collaborations with other COBREs continue to grow, with VCBH PI Dr. Higgins chairing two COBRE External Advisory Committees and serving as a member of a third. In Phase 3, we propose to sustain VCBH competitiveness in obtaining external grant support and fostering new research and dissemination initiatives. We will continue mentoring early career investigators, leveraging our three cores that have strong institutional support and broad reach, and coalescing VCBH collaborations around five areas of scientific strength, each with its own working group. An innovative Pilot Project Program will be leveraged to support early-career investigators and generate preliminary data for grant applications in current areas of strength and to foster new research directions. We are confident that with Phase 3 support, VCBH is well positioned to succeed as a sustainable, impactful, multidisciplinary center of research excellence.

项目摘要 总体方案 本申请的首要目标是成为生物医学研究卓越中心（COBRE）的第三阶段 该奖项是为了在佛蒙特大学建立佛蒙特行为与健康中心（VCBH） (UVM)作为一个可持续的卓越研究中心。这个多学科中心研究关系 个人行为（生活方式）与慢性病和过早死亡风险之间的关系。VCBH制造 在第一阶段和第二阶段取得了相当大的进展，成为一个充满活力和可持续发展的中心。VCBH 建立了外部赠款支持和同行评审出版物的良好记录，总额达1.651亿美元 累计资金，包括COBRE项目领导人（PL）的1830万美元奖励，以及917篇文章 同行评审期刊，包括515份将PL列为第一作者或共同作者的期刊。PLs成功地获得了NIH， 基金会和行业奖项，如PI、项目PI和Co-Is。第一阶段和第二阶段的其他显著成就 包括建立一个NIH支持的UVM烟草监管科学中心，并获得最初的P50奖 这是一个更新为U 54，两次更新NIH T32培训奖在临床成瘾研究现在， 31-36岁，并建立新的HRSA支持的UVM农村成瘾中心和新的NIH T32 神经生物学成瘾研究培训奖。VCBH核心继续支持充满活力的每月讲座 系列，年度全国会议，以及同行评审期刊年度特刊的客座编辑 预防医学基于会议。VCBH与其他COBREs的合作继续增长， VCBH PI希金斯博士主持两个COBRE外部咨询委员会，并担任第三个委员会的成员。在 在第三阶段，我们建议维持VCBH的竞争力，以获得外部资助，并培养新的 研究和传播举措。我们将继续指导早期职业调查人员，利用我们的 三个核心，具有强大的机构支持和广泛的影响力，并结合VCBH合作， 五个领域的科学力量，每个领域都有自己的工作组。一个创新的试点项目计划将是 用于支持早期职业调查人员，并为当前的拨款申请生成初步数据。 优势领域，培育新的研究方向。我们相信，在第三阶段的支持下，VCBH将 作为一个可持续的，有影响力的，多学科的卓越研究中心，我们处于有利地位。