Vermont Center on Behavior and Health

这是生物医学研究卓越中心（COBRE）的第2阶段应用程序，以进一步开发 佛蒙特州行为与健康中心（VCBH）在佛蒙特大学（UVM）。这种多学科 研究中心专注于调查不健康行为模式之间的关系（例如，物质 滥用、缺乏运动、不健康的食物选择、不遵守推荐的医疗方案）， 慢性病和过早死亡的风险。总体科学优先事项是（a）增加 理解对不健康行为模式的脆弱性的机制，以及（B）开发 更有效的行为改变干预措施。这些领域的进步对于改善 美国人口健康，减少健康差距，削减螺旋上升的医疗保健费用。VCBH已经 在第一阶段取得了相当大的进展，建立了一个卓越的生产研究中心， 生物医学研究的重要领域。VCBH目前由20名UVM教职员工组成， 有成就的外部，内部和社区顾问，以及来自其他州的合作者， 超越。目前的教师是多学科的，均匀分布在学术队伍， 在同行评审的期刊上发表了118篇文章，并获得了59 135 320美元的额外收入。 在第一阶段供资的最初四年期间，外部赠款支持。我们建议继续优先考虑 在第二阶段指导有前途的早期职业教师。我们为9名早期职业教师提供了 在第一阶段，利用多要素指导，资助研究项目和职业发展支持 我们将在拟议的供资期内继续评估和完善该计划。我们建议继续 一个促进有效沟通、财政规划和监督的行政核心， 充满活力的知识基础设施，并指导和支持努力获得外部赠款支持。我们有 建立了两个额外的VCBH核心，我们建议继续，行为经济学和干预 科学（BEIS）核心和合作，传播和教育（CDE）核心。BEIS协助 具有决策和神经成像组件的调查人员， 对不健康行为模式的脆弱性，行为改变干预措施的发展，以及经济 干预成本效益模型。CDE支持地方、国家和国际研究 合作，通过每月系列讲座传播新知识，年度全国会议， 同行评审期刊《预防医学》、其他出版物和教育期刊的年度特刊 努力，包括在UVM校园提供的行为和健康研讨会和讲习班， 向合作者和其他感兴趣的人直播。我们有信心继续发展壮大 VCBH按照这一总体管理计划将成功地建立一个多学科中心， 研究卓越的行为和健康与可持续的地方，国家和国际影响。

This is a Phase 2 Center of Biomedical Research Excellence (COBRE) application to further develop the Vermont Center on Behavior and Health (VCBH) at the University of Vermont (UVM). This multidisciplinary research center focuses on investigating relationships between unhealthy behavior patterns (e.g., substance abuse, physical inactivity, unhealthy food choices, non-adherence with recommended medical regimens) and risk for chronic disease and premature death. The overarching scientific priorities are (a) increasing understanding of the mechanisms underpinning vulnerability to unhealthy behavior patterns and (b) developing more effective behavior-change interventions. Advances in each of these areas are essential to improving U.S. population health, reducing health disparities, and curtailing spiraling health care costs. VCBH has made considerable progress in Phase 1 towards establishing a productive center of research excellence in this important area of biomedical research. VCBH currently consists of 20 UVM faculty members, highly accomplished external, internal, and community advisors, and collaborators from other IDeA states and beyond. The current faculty is multidisciplinary, evenly distributed across academic ranks, and highly productive, having published 118 articles in peer-reviewed journals and obtained $59,135,320 in additional external grant support during the initial four years of Phase 1 funding. We propose to continue prioritizing the mentoring of promising early-career faculty in Phase 2. We provided nine early-career faculty members with funded research projects and career-development support during Phase 1, using a multi-element mentoring plan that we will continue evaluating and refining during the proposed funding period. We propose continuing an Administrative Core that promotes effective communication, fiscal planning and oversight, supports a vibrant intellectual infrastructure, and directs and supports efforts to obtain external grant support. We have established two additional VCBH cores that we propose to continue, a Behavioral Economics and Intervention Sciences (BEIS) Core and a Collaboration, Dissemination, and Education (CDE) Core. The BEIS assists investigators with a decision-making and neuroimaging component to examine processes underpinning vulnerability to unhealthy behavior patterns, development of behavior-change interventions, and economic modeling of intervention cost-effectiveness. The CDE supports local, national, and international research collaborations, dissemination of new knowledge through a monthly lecture series, annual national conferences, annual Special Issues of the peer-reviewed journal Preventive Medicine, other publications, and educational efforts including seminars and workshops in behavior and health that are offered on the UVM campus and streamed live to collaborators and interested others. We are confident that continuing to develop and grow VCBH following this overall management plan will succeed in establishing a multidisciplinary center of research excellence in behavior and health with sustainable local, national, and international impact.