Pilot Project Program

项目摘要 试点项目计划 在美国，不健康的行为模式是慢性病和过早死亡的主要驱动因素， 给医疗系统带来巨大的经济负担。佛蒙特州行为与健康中心（VCBH） 致力于通过调查这些不健康行为的基础过程来改善美国的公共健康 发展和传播/实施有效和具有成本效益的行为改变 干预措施。第三阶段试点项目计划的总体目标是在取得进展的基础上， 在第一阶段和第二阶段，建立VCBH作为一个可持续的卓越研究中心。拟议 试点项目计划将在滚动的基础上邀请试点项目申请。试点项目 该计划将优先考虑建立在目前VCBH研究优势基础上的合作研究：（1）烟草 监管科学，（2）烟草控制，（3）农村成瘾危机，（4）心肺研究，（5）研究 神经生物学发育和风险的影响。我们会严格评审申请，以确定有价值的项目 影响力和资金的最大潜力。在有价值的申请中，优先考虑早期- 职业调查员和那些使用VCBH核心的人。早期职业调查人员将获得全面的 遵循COBRE第1和第2阶段建立的做法，由VCBH高级调查员提供指导。试点 将鼓励项目领导人与正在建立的VCBH主题工作组合作 围绕VCBH科学实力的这五个领域，规划R系列中的NIH合作提案， P01和中心赠款申请。我们还将对新研究的机会保持警惕 与VCBH使命一致的方向。总体而言，拟议的试点项目计划将是至关重要的 对于维持VCBH生产力、早期职业指导和生成初步数据非常重要 竞争性NIH和其他拨款申请所必需的，所有这些都是坚定地将VCBH置于 有科学价值和可持续的财政基础。

PROJECT SUMMARY Pilot Project Program Unhealthy behavior patterns are primary drivers of chronic disease and premature death in the U.S. as well as an immense financial burden on the healthcare system. The Vermont Center on Behavior and Health (VCBH) is dedicated to improving U.S. public health by investigating processes underpinning these unhealthy behavior patterns and developing and disseminating/implementing efficacious and cost-effective behavior-change interventions. The overarching aim of this Phase 3 Pilot Project Program is to strategically build upon progress made in Phases 1 and 2 in establishing VCBH as a sustainable center of research excellence. The proposed Pilot Project Program will invite proposals for Pilot Project applications on a rolling basis. The Pilot Project Program will prioritize collaborative research that builds upon five current VCBH research strengths: (1) tobacco regulatory science, (2) tobacco control, (3) rural addiction crisis, (4) cardiopulmonary research, and (5) studies of neurobiological development and risk. Applications will be rigorously evaluated to identify meritorious projects with the greatest potential for impact and funding. Among meritorious applications, priority will be given to early- career investigators and those that utilize VCBH cores. Early-career investigators will receive comprehensive mentorship from VCBH senior investigators adhering to practices established in COBRE Phases 1 and 2. Pilot Project Leaders will be encouraged to collaborate with ongoing VCBH themed working groups established around these five areas of VCBH scientific strength to plan for collaborative NIH proposals in the R series and P01 and center grants applications. We will also be vigilant regarding opportunities to seed new research directions that align with the VCBH mission. Overall, the proposed Pilot Project Program will be critically important to sustaining VCBH productivity, early-career mentoring, and generating the preliminary data necessary for competitive NIH and other grant applications, all essential to firmly situating VCBH on a scientifically meritorious and sustainable fiscal foundation.