CHANGE OF GRANTEE INSTITUTION K23 HL146890 A Systems Approach to Align ICU Care with Patient Treatment Goals

受资助机构变更 K23 HL146890 使 ICU 护理与患者治疗目标保持一致的系统方法

基本信息

项目摘要

ABSTRACT The support of this career development award will help Jacqueline M Kruser, MD MS become an independent physician-investigator with the training and experience necessary to improve communication and treatment decision making for patients with critical illness. Dr. Kruser will use this award to build on her existing foundation in health services and outcomes research to achieve two career development goals: (1) Develop expertise in the application of systems engineering principles and methods in healthcare, and (2) Gain knowledge and experience in the conduct of clinical trials of complex behavioral interventions. These skills will expand Dr. Kruser's research focus beyond individual-level interventions to address the complex, system-level factors that influence treatment decision making and end-of-life care for patients with life-threatening illness, specifically in chronic critical illness. Dr. Kruser will achieve these career objectives through a 5-year career development plan that involves structured didactics, patient-oriented experiential research, and intensive mentoring. Dr. Kruser's career development will be mentored by Jane L Holl MD MPH, a physician with experience in applying systems engineering methods in healthcare, with over 20 years of sustained extramural funding, and an outstanding record of mentorship. The co-mentors of this award are experts in clinical trials and outcomes research in critical care (Richard G Wunderink, MD), and end-of-life decision making and behavioral intervention development (Margaret Schwarze, MD MPP). Dr. Kruser's career development will be supported by the exceptional institutional environment of Northwestern University, including the (1) Dedicated resources from the Division of Pulmonary and Critical Care Medicine and Department of Medicine, (2) Strong research infrastructure of the interprofessional Center for Healthcare Studies (directed by Dr. Holl), and (3) Established, productive collaborations between the McCormick School of Engineering and the Feinberg School of Medicine. Nearly 400,000 people in the US develop chronic critical illness each year, and most older adults with this condition will not survive beyond one year. Studies suggest that many older adults with chronic critical illness who are near the end of life receive unwanted care that does not reflect their goals, values, or preferences, referred to as “goal-discordant” care. Thus, the overall research objective of this award is to apply the tools of systems engineering to adapt an existing individual-level communication tool, “Best Case/Worst Case,” to reduce goal-discordant care in older adults at risk for chronic critical illness. Specific Aim 1 will identify the most impactful ICU system failures in communication and treatment decision-making through a Failure Mode, Effects, and Criticality Analysis. Next, Specific Aim 2 will use user-centered design engineering and simulation testing to adapt “Best Case/Worst Case” to the complex ICU system. Finally, Specific Aim 3 will test the feasibility and acceptability of the novel intervention through a two-site, pilot clinical trial.
摘要

项目成果

期刊论文数量(11)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Reconsidering the Language of Serious Illness.
重新考虑严重疾病的语言。
  • DOI:
    10.1001/jama.2023.11409
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Kruser,JacquelineM;Clapp,JustinT;Arnold,RobertM
  • 通讯作者:
    Arnold,RobertM
Patient-Centered and Family-Centered Care in the Intensive Care Unit.
  • DOI:
    10.1016/j.ccm.2022.05.008
  • 发表时间:
    2022-09
  • 期刊:
  • 影响因子:
    5.7
  • 作者:
    Secunda, Katharine E.;Kruser, Jacqueline M.
  • 通讯作者:
    Kruser, Jacqueline M.
Derivation and performance of an end-of-life practice score aimed at interpreting worldwide treatment-limiting decisions in the critically ill.
  • DOI:
    10.1186/s13054-022-03971-9
  • 发表时间:
    2022-04-13
  • 期刊:
  • 影响因子:
    15.1
  • 作者:
    Mentzelopoulos, Spyros D.;Chen, Su;Nates, Joseph L.;Kruser, Jacqueline M.;Hartog, Christiane;Michalsen, Andrej;Efstathiou, Nikolaos;Joynt, Gavin M.;Lobo, Suzana;Avidan, Alexander;Sprung, Charles L.
  • 通讯作者:
    Sprung, Charles L.
Design thinking to improve healthcare delivery in the intensive care unit: Promise, pitfalls, and lessons learned.
  • DOI:
    10.1016/j.jcrc.2022.153999
  • 发表时间:
    2022-06
  • 期刊:
  • 影响因子:
    3.7
  • 作者:
    Krolikowski KA;Bi M;Baggott CM;Khorzad R;Holl JL;Kruser JM
  • 通讯作者:
    Kruser JM
Defining the Time-limited Trial for Patients with Critical Illness: An Official American Thoracic Society Workshop Report.
定义危重疾病患者的限时试验:美国胸科学会官方研讨会报告。
  • DOI:
    10.1513/annalsats.202310-925st
  • 发表时间:
    2024
  • 期刊:
  • 影响因子:
    8.3
  • 作者:
    Kruser,JacquelineM;Ashana,DeepshikhaC;Courtright,KatherineR;Kross,ErinK;Neville,ThanhH;Rubin,Eileen;Schenker,Yael;Sullivan,DonaldR;Thornton,JDaryl;Viglianti,ElizabethM;Costa,DeenaKelly;Creutzfeldt,ClaireJ;Detsky,Michael
  • 通讯作者:
    Detsky,Michael
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Jacqueline Marie Kruser其他文献

Jacqueline Marie Kruser的其他文献

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{{ truncateString('Jacqueline Marie Kruser', 18)}}的其他基金

Optimizing Time-Limited Trials of Mechanical Ventilation in Acute Respiratory Failure: A Mixed Methods Observational Study
优化急性呼吸衰竭机械通气的限时试验:混合方法观察研究
  • 批准号:
    10633823
  • 财政年份:
    2023
  • 资助金额:
    $ 18.52万
  • 项目类别:
CHANGE OF GRANTEE INSTITUTION K23 HL146890 A Systems Approach to Align ICU Care with Patient Treatment Goals
受资助机构变更 K23 HL146890 使 ICU 护理与患者治疗目标保持一致的系统方法
  • 批准号:
    10324027
  • 财政年份:
    2020
  • 资助金额:
    $ 18.52万
  • 项目类别:
CHANGE OF GRANTEE INSTITUTION K23 HL146890 A Systems Approach to Align ICU Care with Patient Treatment Goals
受资助机构变更 K23 HL146890 使 ICU 护理与患者治疗目标保持一致的系统方法
  • 批准号:
    10406185
  • 财政年份:
    2020
  • 资助金额:
    $ 18.52万
  • 项目类别:
A Systems Approach to Align ICU Care with Patient Treatment Goals
使 ICU 护理与患者治疗目标保持一致的系统方法
  • 批准号:
    9918968
  • 财政年份:
    2019
  • 资助金额:
    $ 18.52万
  • 项目类别:

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