SUPPORT SERVICES FOR HIV AIDS CLINICAL TRIAL NETWORKS

尤尼斯·肯尼迪·施赖弗国家儿童健康和人类发展研究所 (NICHD) 的使命是领导研究和培训，以了解人类发展、改善生殖健康、改善儿童和青少年的生活并优化所有人的能力。 孕产妇和儿科传染病处 (MPIDB) 支持 NICHD 的主要使命之一，即加强孕产妇、儿科和青少年的健康和发展。 该倡议的目标或使命是为关键基础设施提供支持，以加强孕产妇、儿科和青少年艾滋病毒治疗和预防，包括全球范围内的艾滋病毒疫苗研究活动。为了提供参与治疗研究的机会，临床试验中心必须位于受感染妇女和儿童所在的地区。在国内，绝大多数受感染的妇女和儿童是少数族裔和族裔，通常生活在医疗保健系统经常不堪重负且资金不足的城市内城区。在国际上，在资源有限的国家继续进行研究对于解决全球儿童艾滋病毒感染问题至关重要。 然而，在这种环境下临床研究的资助和开展面临着许多挑战，需要一个灵活、反应灵敏的系统，并且最好在以家庭为中心的环境中为母亲和儿童提供协调一致的护理，以优化妇女和儿童在持续医疗保健中的维持。

The mission of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is to lead research and training to understand human development, improve reproductive health, enhance the lives of children and adolescents, and optimize abilities for all. The Maternal and Pediatric Infectious Disease Branch (MPIDB) supports one of the major missions of the NICHD to enhance maternal, pediatric, and adolescent health and development. The objective or mission of this initiative is to provide support for critical infrastructure to enhance maternal, pediatric, and adolescent HIV therapeutics and prevention, including HIV vaccine research activities on a global scale. To provide opportunities to participate in therapeutic research, clinical trial centers must be situated in areas where infected women and children are located. Domestically, the vast majority of infected women and children are of minority race and ethnicity and often live in urban, inner-city areas in which the medical care system is often overwhelmed and under-funded. Internationally, continuing research in resource-limited countries is critical to address the global problem of pediatric HIV infection. The funding and conduct of clinical research in such settings offers many challenges though and requires a system that is flexible and responsive, and that ideally provides coordinated care of the mother and child together in a family-centered setting to optimize the maintenance of both woman and child in ongoing health care.