SUPPORT SERVICES FOR THE PREVENTION AND TREATMENT THROUGH A COMPREHENSIVE CARE CONTINUUM FOR HIV-AFFECTED ADOLESCENTS IN RESOURCE CONSTRAINED SETTINGS (PATC3H) (UG3/UH3) PROGRAM

通过全面护理连续体为资源有限环境中受艾滋病毒影响的青少年提供预防和治疗支持服务 (PATC3H) (UG3/UH3) 计划

• 批准号: 10329848
• 负责人: BARBARA DRIVER
• 金额: $ 67.96万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-12-12 至 2021-12-11
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10329848
• 关键词: Achievement; Adolescent; Affect; Africa South of the Sahara; Award; Brazil; Caring; Clinic; Collaborations; Communication; Communities; Comprehensive Health Care; Conduct Clinical Trials; Continuity of Patient Care; Country; Education; Equipment; Evaluation; Family; Funding; HIV; HIV Infections; Health; Health system; Home; Human Resources; Income; Individual; Infrastructure; Institutes; Intervention; Logistics; Monitor; National Institute of Child Health and Human Development; Outcome; Phase; Policies; Prevention; Public Health; Research; Research Activity; Research Personnel; Research Project Grants; Resources; Risk; Services; Structure; Task Performances; U-Series Cooperative Agreements; United States National Institutes of Health; Viral; Youth; base; efficacious intervention; improved; innovation; prevention service; programs; web site

Introduction The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) requires support for logistical and operational coordination, website and communication management, regulatory, and monitoring of research activities for the Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource Constrained Settings (PATC3H) (UG3/UH3) Program. The NICHD and partner NIH Institutes have funded 8 PATC3H awards in Brazil and throughout sub- Saharan Africa in 2018 through a phased innovation cooperative agreement mechanism for interventions of high public health significance: The prevention of new HIV infections among adolescents at risk, and the identification of, linkage to and retention in care of, and long-term viral suppression among youth living with HIV in low-to-middle income countries with high HIV burden. Investigators will evaluate a variety of innovative combination interventions aimed at several levels, including individual, family, clinic, community, structural and education and health systems. Projects include collaborations with local agencies and regulatory bodies, including policy and program leaders, to advance achievement of the research objectives, and maximize implementation and sustainability of efficacious interventions and best practices. Objectives This Task Order will provide all the necessary services, qualified personnel, materials, equipment, and facilities needed for support of a) logistical and operational coordination, b) regulatory infrastructure and monitoring of non-registrational trials, and c) website administration and communication management of research activities for all 8 PATC3H research projects to conduct clinical trials for the evaluation of a variety of combination interventions aimed at the individual, family, clinic, community, structural and education and health systems levels to improve health outcomes among adolescents at risk for and youth living with HIV. https://www.patc3h.org/SitePages/Home.aspx The period of performance of this task order is a base year and 4 option years or a maximum of 5 years.

介绍 尤尼斯·肯尼迪·施赖弗国家儿童健康与人类发展研究所 (NICHD) 需要后勤和运营协调、网站和通信方面的支持 预防和治疗研究活动的管理、监管和监测 通过为资源有限的受艾滋病毒影响的青少年提供全面的连续护理 设置 (PATC3H) (UG3/UH3) 程序。 NICHD 和合作伙伴 NIH 研究所已资助巴西和整个子地区的 8 个 PATC3H 奖项 撒哈拉非洲2018年通过分阶段创新合作协议机制 具有高度公共卫生意义的干预措施：预防新发艾滋病毒感染 处于危险中的青少年，以及识别、联系和保留照顾以及长期病毒 在艾滋病毒负担较高的中低收入国家，对感染艾滋病毒的青年进行抑制。 研究人员将评估针对多个层面的各种创新组合干预措施， 包括个人、家庭、诊所、社区、结构以及教育和卫生系统。项目 包括与当地机构和监管机构（包括政策和项目领导者）的合作， 促进研究目标的实现，并最大限度地实施和可持续性 有效的干预措施和最佳实践。 目标 该任务订单将提供所有必要的服务、合格的人员、材料、设备和 支持 a) 后勤和运营协调、b) 监管基础设施所需的设施 和非注册试验的监测，以及 c) 网站管理和沟通 管理所有 8 个 PATC3H 研究项目的研究活动，以进行临床试验 评估针对个人、家庭、诊所、社区、 结构、教育和卫生系统层面，以改善青少年的健康状况 艾滋病毒感染者和青少年的风险。 https://www.patc3h.org/SitePages/Home.aspx 该任务订单的执行期限为一个基准年和 4 个选项年或最多 5 个 年。