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SYNAPTIC TRANSMISSION IN TRIGEMINAL SUBNUCLEUS CAUDALIS

SYNAPTIC TRANSMISSION IN TRIGEMINAL SUBNUCLEUS CAUDALIS
三叉神经尾亚核的突触传递
批准号：
3425522
负责人：
LI-YEN M HUANG
金额：
$1.98万
依托单位：
UNIVERSITY OF TEXAS MED BR GALVESTON
依托单位国家：
美国
项目类别：
财政年份：
1990
资助国家：
美国
项目状态：
已结题
起止时间：
1990-04-01 至 1992-03-31
来源：
https://reporter.nih.gov/project-details/3425522
关键词：
action potentials afferent nerve analgesia laboratory rat medulla oblongata neural information processing neural transmission oral facial pain pain synapses thalamus

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中文摘要
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英文摘要
This research project is concerned with the functional role of the trigeminal (V) spinal subnucleus caudalis in the processing of pain information. Our long term goal is to determine how pain information is transmitted and regulated in the central nervous system. The specific goal of this proposal is to examine primary afferent-evoked synaptic responses and the action potential in trigeminothalamic neurons in thin medulla slices. The ionic currents and single channel activities of trigeminothalamic neurons will be measured using patch clamp recording techniques. The information obtained will enhance our understanding of the role that trigeminal system has in processing pain-related messages and will facilitate the designing of the therapy for the treatment of orofacial pain.
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Neuronal-Glia Interactions in Trigeminal Ganglia as a Basis for Future Therapy
Neuronal-Glia Interactions in Trigeminal Ganglia as a Basis for Future Therapy
Neuronal-Glia Interactions in Trigeminal Ganglia as a Basis for Future Therapy
NEURON-GLIA INTERACTIONS IN TRIGEMINAL GANGLIA AS A BASIS FOR FUTURE THERAPY
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