Novel therapeutic interventions for the orthopaedic complications of Neurofibromatosis type 1 (NF1).

针对 1 型神经纤维瘤病 (NF1) 骨科并发症的新型治疗干预措施。

• 批准号: nhmrc : 1003478
• 负责人: A/Pr Aaron Schindeler
• 金额: $ 41.9万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-therapeutic-interventions-1-nf1/108936
• 关键词: Novel; therapeutic; interventions; orthopaedic; complications

Children with the genetic disease NF1 can develop fractures that fail to unite and this can lead to amputation. We have advanced models of NF1-deficient bone cells and fracture healing that we will use to test new pharmaceutical treatments for NF1.

患有遗传性疾病NF1的儿童可能会发生骨折，无法愈合，这可能导致截肢。我们有NF1缺陷骨细胞和骨折愈合的先进模型，我们将用它来测试NF1的新药物治疗。