Prevention and treatment of bone infection with CSA-90

CSA-90防治骨感染

• 批准号: nhmrc : GNT1106982
• 负责人: A/Pr Aaron Schindeler
• 金额: $ 35.1万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/prevention-treatment-bone-csa-90/1346549
• 关键词: Prevention; treatment; bone; infection; CSA

Bone infections are a major challenge to treat, especially with the rise of drug resistant “superbugs”. We have access to a new agent, CSA-90, that has dual properties of being anti-microbial (antibiotic) and helps encourage bone growth. This project aims to expand upon our prior research and test CSA-90 for the treatment of chronic bone infections. We will also look at applying this technology to joint replacements and this drug may be particularly useful for coating orthopaedic implants.

骨感染是治疗的一项重大挑战，尤其是随着耐药“超级细菌”的兴起。我们获得了一种新制剂 CSA-90，它具有抗微生物（抗生素）和有助于促进骨骼生长的双重特性。该项目旨在扩展我们之前的研究并测试 CSA-90 治疗慢性骨感染的效果。我们还将考虑将这项技术应用于关节置换术，这种药物对于涂覆骨科植入物可能特别有用。